The Extracellular RNA Communication Consortium has published 500+ research articles since its inception in 2013. Articles in the category “Resources and Technology” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.

Resources and Technology

2019

Rozowsky J et al.

exceRpt: A comprehensive analytic platform for extracellular RNA profiling.

Cell Syst AOP 2019-03-29.
 

Zhang Q et al.

Transfer of functional cargo in exomeres.

Cell Rep AOP 2019-03-26.
  

Murillo OD et al.

exRNA Atlas analysis reveals distinct extracellular RNA Cargo types and their carriers present across human biofluids.

Cell (2019) 177:463-477.e15.
    

Srinivasan S et al.

Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation.

Cell (2019) 177:446-462.e16.
 

Zaborowski MP et al.

Methods for systematic identification of membrane proteins for specific capture of cancer-derived extracellular vesicles.

Cell Rep (2019) 27:255-268.e6.
 

Belair CD et al.

High-throughput, efficient, and unbiased capture of small RNAs from low-input samples for sequencing.

Sci Rep (2019) 9:2262.
 

2018

Godoy PM et al.

Large differences in small RNA composition between human biofluids.

Cell Rep (2018) 25:1346-1358.
  

Haraszti RA et al.

Exosomes produced from 3D Cultures of MSCs by Tangential Flow Filtration show higher yield and improved activity.

Mol Ther (2018) 26:2838-2847.
  

Giraldez MD et al.

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.

Nat Biotechnol (2018) 36:746-757.
 

Dluzen DF et al.

Extracellular RNA profiles with human age.

Aging Cell (2018) 17:e12785.
  

Max KEA et al.

Human plasma and serum extracellular small RNA reference profiles and their clinical utility.

Proc Natl Acad Sci USA (2018) 115 :E5334-E5343.
 

Heintz-Buschart A et al.

Small RNA profiling of low biomass samples: Identification and removal of contaminants.

BMC Biol (2018) 16:52.
 

Yeri A et al.

Evaluation of commercially available small RNASeq library preparation kits using low input RNA.

BMC Genomics (2018) 19:331.
 

Vujic A et al.

Exercise induces new cardiomyocyte generation in the adult mammalian heart.

Nat Commun (2018) 9:1659.
   

Li K et al.

Isolation of plasma lipoproteins as a source of extracellular RNA.

Methods Mol Biol (2018) 1740:139-153.
 

Matsuda A & Patel T.

Milk-derived extracellular vesicles for therapeutic delivery of small interfering RNAs.

Methods Mol Biol (2018) 1740:187-197.
  

Shukla N, Yan IK & Patel T.

Multiplexed detection and quantitation of extracellular vesicle RNA expression using NanoString.

Methods Mol Biol (2018) 1740:177-185.
 

Didiot MC et al & .

Loading of extracellular vesicles with hydrophobically modified siRNAs.

Methods Mol Biol (2018) 1740:199-214.
 

Li K et al & .

Cushioned-Density Gradient Ultracentrifugation (C-DGUC): A refined and high performance method for the isolation, characterization, and use of exosomes.

Methods Mol Biol (2018) 1740:69-83.
 

Filant J et al.

Isolation of extracellular RNA from serum/plasma.

Methods Mol Biol (2018) 1740:43-57.
 

Yan IK, Lohray R & Patel T.

Droplet digital PCR for quantitation of extracellular RNA.

Methods Mol Biol (2018) 1740:155-162.
 

Etheridge A et al & .

Preparation of small RNA NGS libraries from biofluids.

Methods Mol Biol (2018) 1740:163-175.
 

Yan IK, Berdah VX & Patel T.

Isolation of extracellular RNA from bile.

Methods Mol Biol (2018) 1740:59-67.
 

Shao H et al.

New technologies for analysis of extracellular vesicles.

Chem Rev (2018) 118:1917-1950.
 

2017

Amorim MG et al.

A total transcriptome profiling method for plasma-derived extracellular vesicles: Applications for liquid biopsies.

Sci Rep (2017) 7:14395.
 

Wei Z et al.

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells.

Nat Commun (2017) 8:1145.
  

Nolan JP & Duggan E.

Analysis of individual extracellular vesicles by flow cytometry.

Methods Mol Biol (2018) 1678:79-92.
 

Wu X et al.

sRNAnalyzer: a flexible and customizable small RNA sequencing data analysis pipeline.

Nucleic Acids Res (2017) 45:12140-12151.
 

Kaczor-Urbanowicz KE et al.

Novel approaches for bioinformatic analysis of salivary RNA sequencing data for development.

Bioinformatics (2018) 34:1-8.
 

Wu AY & Lai CP.

Tracking extracellular vesicles delivery and RNA translation using multiplexed reporters.

Methods Mol Biol (2017) 1660:255-265.
 

Gogakos T et al.

Characterizing expression and processing of precursor and mature human tRNAs by hydro-tRNAseq and PAR-CLIP.

Cell Rep (2017) 20:1463-1475.
 

Saugstad JA et al.

Analysis of extracellular RNA in cerebrospinal fluid.

J Extracell Vesicles (2017) 6:1317577.
 

Jayaram H et al.

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: a pilot study.

Invest Ophthalmol Vis Sci (2017) 58:2884-2890.
  

Mateescu B et al.

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper.

J Extracell Vesicles (2017) 6:1286095.
  

Nolan JP & Jones JC.

Detection of platelet vesicles by flow cytometry.

Platelets (2017) 28:256-262.
  

Danielson KM et al.

High throughput sequencing of extracellular RNA from human plasma.

PLoS ONE (2017) 12:e0164644.
 

Lee I et al.

The importance of standardization on analyzing circulating RNA.

Mol Diagn Ther (2017) 21:259-268.
  

2016

Baldwin S et al.

Analyzing the miRNA content of extracellular vesicles by fluorescence nanoparticle tracking.

Nanomedicine (2017) 13:765-770.
 

Majem B et al.

RNA sequencing analysis of salivary extracellular RNA.

Methods Mol Biol (2017) 1537:17-36.
 

Haraszti RA et al.

High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.

J Extracell Vesicles (2016) 5:32570.
  

Wei Z et al.

Fetal bovine serum RNA interferes with the cell culture derived extracellular RNA.

Sci Rep (2016) 6:31175.
 

Higginbotham JN et al.

Identification and characterization of EGF receptor in individual exosomes by Fluorescence-Activated Vesicle Sorting.

J Extracell Vesicles (2016) 5:29254.
 

Freedman JE et al.

Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma.

Nat Commun (2016) 7:11902.
 

Shah R et al.

Discordant expression of circulating microRNA from cellular and extracellular sources.

PLoS ONE (2016) 11:e0153691.
 

Freedman JE et al.

Diverse human extracellular RNAs are widely detected in human plasma.

Nat Commun (2016) 7:11106.
 

Cheung KH et al.

Extending gene ontology in the context of extracellular RNA and vesicle communication.

J Biomed Semantics (2016) 7:19.
 

Akers JC et al.

Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid.

Cancer Biomark (2016) 17:125-32.
 

Tanriverdi K et al.

Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative Polymerase Chain Reaction.

Anal Biochem (2016) 501:66-74.
 

Zaborowski MP et al.

Extracellular vesicles: Composition, biological relevance, and methods of study.

Bioscience (2015) 65:783-797.
   

Xiao H et al.

Differential proteomic analysis of human saliva using Tandem Mass Tags quantification for gastric cancer detection.

Sci Rep (2016) 6:22165.
 

Akers JC et al.

Comparative analysis of technologies for quantifying extracellular vesicles (EVs) in clinical cerebrospinal fluids (CSF).

PLoS ONE (2016) 11:e0149866.
 

Yuan T et al.

Plasma extracellular RNA profiles in healthy and cancer patients.

Sci Rep (2016) 6:19413.
 

Ben-Dov IZ et al.

Cell and microvesicle urine microRNA deep sequencing profiles from healthy individuals: Observations with potential impact on biomarker studies.

PLoS ONE (2016) 11:e0147249.
 

Danielson KM et al.

Diurnal variations of circulating extracellular vesicles measured by nano flow cytometry.

PLoS ONE (2016) 11:e0144678.
 

2015

Keerthikumar S et al.

ExoCarta: A web-based compendium of exosomal cargo.

J Mol Biol (2016) 428:688-692.
  

Schwarzenbach H et al.

Data normalization strategies for microRNA quantification.

Clin Chem (2015) 61:1333-42.
 

Subramanian SL et al.

Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies.

J Extracell Vesicles (2015) 4:27497.
 

Laurent LC et al.

Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.

J Extracell Vesicles (2015) 4:26533.
   

Ainsztein AM et al.

The NIH Extracellular RNA Communication Consortium.

J Extracell Vesicles (2015) 4:27493.
      

Li X, Mauro M & Williams Z.

Comparison of plasma extracellular RNA isolation kits reveals kit-dependent biases.

Biotechniques (2015) 59:13-7.
 

Lai CP et al.

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.

Nat Commun (2015) 6:7029.
 

Shao H et al.

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma.

Nat Commun (2015) 6:6999.
 

Tewari M.

A functional extracellular transcriptome in animals? Implications for biology, disease and medicine.

Genome Biol (2015) 16:47.
   

Chiang SH et al.

RNAPro*SAL: a device for rapid and standardized collection of saliva RNA and proteins.

Biotechniques (2015) 58:69-76.
 

2014

Lotvall J et al.

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.

J Extracell Vesicles (2014) 3:26913.
  

Kim DK et al.

EVpedia: a community web portal for extracellular vesicles research.

Bioinformatics (2015) 31:933-9.
 

Bahn JH et al.

The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva.

Clin Chem (2015) 61:221-30.
  

Takahashi K et al.

Analysis of extracellular RNA by digital PCR.

Front Oncol (2014) 4:129.
 

Grange C et al.

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging.

Int J Mol Med (2014) 33:1055-63.
    

Ben-Dov IZ et al.

Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: Description of miRNA profiles at baseline.

PLoS ONE (2014) 9:e86856.
  

Lai CP et al.

Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter.

ACS Nano (2014) 8:483-94.
    

2013

Chen WW et al.

BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles.

Mol Ther Nucleic Acids (2013) 2:e109.