Data

Data

   

exRNA Atlas (open access)

exRNA Atlas (consortium login)

The exRNA Atlas is developed and maintained by the Data Management and Resource Repository (DMRR). It includes exRNA profiles derived from various biofluids and conditions and currently stores data profiled from small RNA sequencing assays. The datasets are uniformly processed using the exceRpt small RNA-seq pipeline. Faceted filtering and data navigation tools are enabled by rich metadata standards developed by the consortium and metadata annotations contributed by the data producers. Uniform data quality metrics agreed by the consortium are applied to all datasets. The Atlas will be updated regularly with new profiles. Using the consortium login option gives ERC consortium members access to datasets which have not yet been pubicly released.

View this video tutorial to explore the various features available in the exRNA Atlas.

   

Data Access Policy Summary

Data Quality Control Standards

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Data Coordination Center

The wiki at the ERC Consortium's Data Coordination Center includes information about the DCC data submission pipeline.

   

Data Use Cases

The DMRR has developed several use cases based on consortium members' datasets and publications. The purpose of these use cases is to highlight the software tools developed by the DMRR, with the long-term goal that all future datasets generated by the consortium can be analyzed reproducibly and compared to each other.

  • Use Case 1: Exogenous exRNA (pdf, pptx, article)
  • Use Case 2: exRNA in Alzheimer's and Parkinson's Diseases
    • Use Case 2 Part 1: The exceRpt Pipeline (pdf, pptx, data, article)
    • Use Case 2 Part 2: The exRNA Atlas, DEseq and exceRpt pipelines, Vesiclepedia, and Pathway Analysis (pdf, data, article)
  • Use Case 3: Biomarker Potential and Limitations of Circulating miRNA (pdf, pptx, data, article)