The consortium is working internally to compare Standard Operating Procedures (SOPs), i.e. protocols used by different labs for extracellular vesicle preparation and RNA analysis. Vetted results are here.
This decision tree allows a beginner to understand the best approaches available in the field to study extracellular vesicles and extracellular RNA. See this blog post for an in-depth discussion of how to select protocols from this page.
Collection of Biofluids
Isolation and Enrichment of Extracellular Vesicles
Validation and Quantification
Proteomics on Extracellular Vesicles