The Extracellular RNA Communication Consortium has published 700+ research articles since its inception in 2013. Articles in the category “Biomarkers” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Su Y et al.
Multiple early factors anticipate post-acute COVID-19 sequelae.
Max KEA et al.
Clin Chem (2021) 67:1676-1688.
Hao N et al.
Acoustofluidic multimodal diagnostic system for Alzheimer’s disease.
Biosens Bioelectron (2022) 196:113730.
Ma S et al.
Satake E et al.
J Am Soc Nephrol (2021) 32:2331-2351.
Blanco-Dominguez R et al.
A novel circulating microRNA for the detection of acute myocarditis.
N Engl J Med (2021) 384:2014-2027.
Muthukumar T et al.
Transplantation (2022) 106:806-820.
Chen L et al.
Anal Chem (2021) 93:6456-6462.
Crouser ED et al.
Muralidharan K et al.
TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas.
Clin Cancer Res (2021) 27:169-178.
Sandau US et al.
Performance of validated microRNA biomarkers for Alzheimer’s disease in mild cognitive impairment.
J Alzheimers Dis (2020) 78:245-263.
Srinivasan S et al.
Charest A.
Adv Biosyst (2020) 4:e2000069.
Vaze A et al.
Meabon JS et al.
J Neurol Sci (2020) 417:117049.
Li F et al.
Cancers (Basel) (2020) 12:2041.
Shukuya T et al.
J Thorac Oncol (2020) 15:1773-1781.
Yekula A et al.
Adv Biosyst (2020) 4:e2000029.
Hao N et al.
Acoustofluidics-assisted engineering of multifunctional three-dimensional zinc oxide nanoarrays.
Ahn JY et al.
Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria.
Biochim Biophys Acta Gen Subj (2021) 1865:129598.
Tran AM et al.
Front Cell Dev Biol (2020) 8:50.
Yekula A et al.
From laboratory to clinic: Translation of extracellular vesicle based cancer biomarkers.
Rao SL et al.
Altered level of salivary placental growth factor is associated with preeclampsia.
Ghai V et al.
J Neurotrauma (2020) 37:1418-1430.
Silverman MG et al.
Circulating miRNAs and risk of sudden death in patients with coronary heart disease.
JACC Clin Electrophysiol (2020) 6:70-79.
Wang Z et al.
Sun L et al.
Theranostics (2019) 9:8409-8425.
Jones PS et al.
Lee MY et al.
Distinct profiles of cell-free microRNAs in plasma of veterans with Post-Traumatic Stress Disorder.
Kaczor-Urbanowicz KE et al.
Clinical validity of saliva and novel technology for cancer detection.
Biochim Biophys Acta Rev Cancer (2019) 1872:49-59.
Petrescu GED et al.
MicroRNA based theranostics for brain cancer: Basic principles.
J Exp Clin Cancer Res (2019) 38:231.
Lee MY et al.
A biological function based biomarker panel optimization process.
Ghai V et al.
Giraldez MD et al.
Gonzalez-Villasana V et al.
Dis Markers (2019) 2019:6852917.
Bach DH, Lee SK & Sood AK.
Mol Ther Nucleic Acids (2019) 16:118-129.
Dawes C & Wong DTW.
Role of saliva and salivary diagnostics in the advancement of oral health.
Ghai V et al.
Circulating RNAs as predictive markers for the progression of type 2 diabetes.
J Cell Mol Med (2019) 23:2753-2768.
Wiedrick JT et al.
Validation of microRNA biomarkers for Alzheimer’s Disease in human cerebrospinal fluid.
J Alzheimers Dis (2019) 67:875-891.
Pua HH et al.
Cell Rep (2019) 26:933-944.e4.
Varkaris A et al.
Br J Cancer (2019) 120:340-345.
Gulei D et al.
CRISPR-based RNA editing: Diagnostic applications and therapeutic options.
Expert Rev Mol Diagn (2019) 19:83-88.
Lusardi TA et al.
Analytics of Cerebrospinal Fluid microRNA quantitative PCR studies.
Mol Neurobiol (2019) 56:4988-4999.
Smith EMD et al.
Clin Immunol (2019) 198:71-78.
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Hinger SA et al.
Cell Rep (2018) 25:715-725.e4.
Wei F et al.
J Mol Diagn (2018) 20:738-742.
Antoury L et al.
Narla V et al.
Unique circulating microRNA profiles in HIV infection.
J Acquir Immune Defic Syndr (2018) 79:644-650.
Regev K et al.
Identification of MS-specific serum miRNAs in an international multicenter study.
Neurol Neuroimmunol Neuroinflamm (2018) 5:e491.
Li F et al.
Clin Chem (2018) 64:1513-1521.
Shah RV et al.
Associations of circulating extracellular RNAs with myocardial remodeling and heart failure.
JAMA Cardiol (2018) 3:871-876.
Silva AM et al.
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response.
Theranostics (2018) 8:3902-3917.
Ghai V et al.
Kidney Int Rep (2018) 3:555-572.
Danielson KM et al.
Plasma circulating extracellular RNAs in Left Ventricular Remodeling post-Myocardial Infarction.
EBioMedicine (2018) 32:172-181.
Kaczor-Urbanowicz KE et al.
Salivary exRNA biomarkers to detect gingivitis and monitor disease regression.
J Clin Periodontol (2018) 45:806-817.
Koupenova M et al.
Micro RNAs from DNA viruses are found widely in plasma in a large observational human population.
Fallen S et al.
J Cell Mol Med (2018) 22:2760-2773.
Nonaka T & Wong DTW.
Liquid biopsy in head and neck cancer: Promises and challenges.
Baecher-Allan C, Kaskow BJ & Weiner HL.
Multiple Sclerosis: Mechanisms and immunotherapy.
Raheja R et al.
Correlating serum microRNAs and clinical parameters in amyotrophic lateral sclerosis.
Muscle Nerve (2018) 58:261-269.
Shah R et al.
Circ Heart Fail (2018) 11:e004278.
Reategui E et al.
Bei Y et al.
Extracellular vesicles in cardiovascular theranostics.
Theranostics (2017) 7:4168-4182.
Related Pathway
Wei Z et al.
Coding and noncoding landscape of extracellular RNA released by human glioma stem cells.
Willinger CM et al.
Circ Cardiovasc Genet (2017) 10:5.
Shah R et al.
Am J Physiol Heart Circ Physiol (2017) 313:H1162-H1167.
Shankar GM et al.
Liquid biopsy for brain tumors.
Expert Rev Mol Diagn (2017) 17:943-947.
Jones A et al.
miRNA signatures of insulin resistance in obesity.
Vasilescu C et al.
Zhang Y et al.
Salivary extracellular RNA biomarkers for insulin resistance detection in Hispanics.
Diabetes Res Clin Pract (2017) 132:85-94.
Jayaram H et al.
Invest Ophthalmol Vis Sci (2017) 58:2884-2890.
Fuentes-Mattei E et al.
Plasma viral miRNAs indicate a high prevalence of occult viral infections.
EBioMedicine (2017) 20:182-192.
Figueroa JM et al.
Neuro Oncol (2017) 19:1494-1502.
Klingenberg M et al.
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.
J Hepatol (2017) 67:603-618.
Related Pathways: 1, 2
Mick E et al.
Stroke and circulating extracellular RNAs.
He Y et al.
A systematic study of dysregulated microRNA in Type 2 Diabetes Mellitus.
Xiao J et al.
Circulating miR-30d predicts survival in patients with acute heart failure.
Cell Physiol Biochem (2017) 41:865-874.
Shah R et al.
Extracellular RNAs are associated with insulin resistance and metabolic phenotypes.
Diabetes Care (2017) 40:546-553.
McManus DD et al.
Messenger RNA and microRNA transcriptomic signatures of cardiometabolic risk factors.
Regev K et al.
JAMA Neurol (2017) 74:275-285.
Wang X, Kaczor-Urbanowicz KE & Wong DT.
Salivary biomarkers in cancer detection.
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases.
Best Pract Res Clin Endocrinol Metab (2016) 30:577-590.
Kaczor-Urbanowicz KE et al.
Saliva diagnostics – Current views and directions.
Exp Biol Med (Maywood) (2017) 242:459-472.
Dou Y et al.
Kaczor-Urbanowicz KE et al.
Emerging technologies for salivaomics in cancer detection.
J Cell Mol Med (2017) 21:640-647.
Lusardi TA et al.
MicroRNAs in human cerebrospinal fluid as biomarkers for Alzheimer’s disease.
J Alzheimers Dis (2017) 55:1223-1233.
Kanlikilicer P et al.
Ubiquitous release of exosomal tumor suppressor miR-6126 from ovarian cancer cells.
Cancer Res (2016) 76:7194-7207.
Regev K et al.
Comprehensive evaluation of serum microRNAs as biomarkers in Multiple Sclerosis.
Neurol Neuroimmunol Neuroinflamm (2016) 3:e267.
Smith EM et al.
Pediatr Nephrol (2017) 32:283-295.
Ghai V & Wang K.
Recent progress toward the use of circulating microRNAs as clinical biomarkers.
Arch Toxicol (2016) 90:2959-2978.
Yan IK et al.
Circulating extracellular RNA markers of liver regeneration.
Wu S et al.
Circulating microRNAs and life expectancy among identical twins.
Ann Hum Genet (2016) 80:247-56.
Van Roosbroeck K & Calin GA.
MicroRNAs in chronic lymphocytic leukemia: miRacle or miRage for prognosis and targeted therapies?
Byron SA et al.
Translating RNA sequencing into clinical diagnostics: Opportunities and challenges.
Nat Rev Genet (2016) 17:257-71. Related blog post
Rennert RC, Hochberg FH & Carter BS.
ExRNA in biofluids as biomarkers for brain tumors.
Cell Mol Neurobiol (2016) 36:353-60.
Sun Y et al.
Examining plasma microRNA markers for colorectal cancer at different stages.
Melman YF et al.
Circulation (2016) 133:e389-90.
Gleber-Netto FO et al.
Salivary biomarkers for detection of oral squamous cell carcinoma in a Taiwanese population.
Clin Cancer Res (2016) 22:3340-7.
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers.
Xu T et al.
Mohankumar S & Patel T.
Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer.
Brief Funct Genomics (2016) 15:249-56.
Monroig-Bosque Pdel C, Rivera CA & Calin GA.
MicroRNAs in cancer therapeutics: “From the bench to the bedside”.
Expert Opin Biol Ther (2015) 15:1381-5.
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Laurent LC et al.
J Extracell Vesicles (2015) 4:26533.
Quinn JF et al.
Extracellular RNAs: Development as biomarkers of human disease.
J Extracell Vesicles (2015) 4:27495.
Lin X et al.
Noncoding RNAs in human saliva as potential disease biomarkers.
Melman YF et al.
Circulation (2015) 131:2202-16.
Akers JC et al.
miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients.
J Neurooncol (2015) 123:205-16.
Majem B et al.
Non-coding RNAs in saliva: Emerging biomarkers for molecular diagnostics.
Int J Mol Sci (2015) 16:8676-98.
Saugstad JA.
Non-coding RNAs in stroke and neuroprotection.
Wong DT.
Salivary extracellular noncoding RNA: Emerging biomarkers for molecular diagnostics.
Ho GY et al.
Differential expression of circulating microRNAs according to severity of colorectal neoplasia.
Guzman N et al.
Mol Cancer Res (2015) 13:891-901.
Boukouris S & Mathivanan S.
Exosomes in bodily fluids are a highly stable resource of disease biomarkers.
Proteomics Clin Appl (2015) 9:358-67.
George J & Patel T.
Noncoding RNA as therapeutic targets for hepatocellular carcinoma.
Semin Liver Dis (2015) 35:63-74.
Srivastava A et al.
Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment.
Curr Gene Ther (2015) 15:182-92.
Fuentes L, Yakob M & Wong DT.
Emerging horizons of salivary diagnostics for periodontal disease.
Sato-Kuwabara Y et al.
Kawikova I & Askenase PW.
Diagnostic and therapeutic potentials of exosomes in CNS diseases.
Haga H & Patel T.
Molecular diagnosis of intrahepatic cholangiocarcinoma.
J Hepatobiliary Pancreat Sci (2015) 22:114-23.
Braicu C et al.
Exosomes as divine messengers: Are they the Hermes of modern molecular oncology?
Cell Death Differ (2015) 22:34-45.
Akat KM et al.
Proc Natl Acad Sci U S A (2014) 111:11151-6.
Yakob M et al.
Curr Oral Health Rep (2014) 1:133-141.
Redzic JS et al.
Extracellular RNA mediates and marks cancer progression.
Semin Cancer Biol (2014) 28:14-23.
Patel T.
Hochberg FH et al.
Glioma diagnostics and biomarkers: An ongoing challenge in the field of medicine and science.
Expert Rev Mol Diagn (2014) 14:439-52.
Ben-Dov IZ et al.
McManus DD et al.
Akers JC et al.
Chen WW et al.
Mol Ther Nucleic Acids (2013) 2:e109.
Lau C et al.
Role of pancreatic cancer-derived exosomes in salivary biomarker development.
J Biol Chem (2013) 288:26888-97.
Gonda DD et al.