The Extracellular RNA Communication Consortium has published 700+ research articles since its inception in 2013. Most of our work is in the fields of extracellular RNA and extracellular vesicle biology, but the ERCC has also supported work in related areas like cancer signaling, RNA structure, and the function of microRNAs inside the cell. Those articles are listed here in reverse chronological order. You can browse different article categories using the drop-down menu at the top of the page.

Additional ERCC Research

2021

Yu X et al.

Ultrasensitive amyloid beta-protein quantification with high dynamic range using a hybrid graphene-gold surface-enhanced Raman spectroscopy platform.

J Raman Spectrosc (2020) 51:432-441.

Li J et al.

Angiotensin II-induced muscle atrophy via PPARgamma suppression is mediated by miR-29b.

Mol Ther Nucleic Acids (2021) 23:743-756.

Chen C et al.

Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae.

Nat Commun (2021) 12:1118.

Palace SG et al.

Yersinia pestis escapes entrapment in thrombi by targeting platelet function.

J Thromb Haemost (2020) 18:3236-3248.

2020

Guo C et al.

The D614G mutation enhances the lysosomal trafficking of SARS-CoV-2 spike.

bioRxiv AOP 2020-12-09.

Kunert-Graf J, Sakhanenko N & Galas D.

Partial information decomposition and the information delta: A geometric unification disentangling non-pairwise information.

Entropy (Basel) (2020) 22:1333.

Su Y et al.

Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19.

Cell (2020) 183:1479-1495.e20.

Muralidharan K et al.

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas.

Clin Cancer Res (2021) 27:169-178.

Charest A.

Experimental and biological insights from proteomic analyses of extracellular vesicle cargos in normalcy and disease.

Adv Biosyst (2020) 4:e2000069.

Chen B et al.

The long noncoding RNA CCAT2 induces chromosomal instability through BOP1 – AURKB signaling.

Gastroenterology (2020) 159:2146-2162.e33.

Meabon JS et al.

Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure.

J Neurol Sci (2020) 417:117049.

Li F et al.

Ultra-short circulating tumor DNA (usctDNA) in plasma and saliva of Non-Small Cell Lung Cancer (NSCLC) patients.

Cancers (Basel) (2020) 12:2041.

Chiu LS et al.

The association of non-alcoholic fatty liver disease and cardiac structure and function-Framingham Heart Study.

Liver Int (2020) 40:2445-2454.

Lurie E et al.

Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin.

Oncogenesis (2020) 9:62.

Chen F et al.

Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in Acute Myeloid Leukaemia: Therapeutic implications.

J Cell Mol Med (2020) 24:7378-7392.

Zhang L et al.

A cell-phone-based acoustofluidic platform for quantitative point-of-care testing.

ACS Nano (2020) 14:3159-3169.

Kang P et al.

Acoustic tweezers based on circular, slanted-finger interdigital transducers for dynamic manipulation of micro-objects.

Lab Chip (2020) 20:987-994.

Xiong C et al.

Targeting forward and reverse EphB4/EFNB2 signaling by a peptide with dual functions.

Sci Rep (2020) 10:520.

2019

Parashar D et al.

miRNA551b-3p activates an oncostatin signaling module for the progression of triple-negative breast cancer.

Cell Rep (2019) 29:4389-4406.e10.

Ding EY et al.

Accuracy and usability of a novel algorithm for detection of irregular pulse using a smartwatch among older adults: Observational study.

JMIR Cardio (2019) 3:e13850.

Darling CE et al.

Bioimpedance-based heart failure deterioration prediction using a prototype fluid accumulation vest-mobile phone dyad: an observational study.

JMIR Cardio (2017) 1:e1.

Spartano NL et al.

Comparison of on-site versus remote mobile device support in the Framingham Heart Study using the health eHeart study for digital follow-up: Randomized pilot study set within an observational study design.

JMIR Mhealth Uhealth (2019) 7:e13238.

Dias MM et al.

GLS2 is protumorigenic in breast cancers.

Oncogene (2020) 39:690-702.

Yoneshiro T et al.

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

Nature (2019) 572:614-619.

Batki J et al.

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.

Nat Struct Mol Biol (2019) 26:720-731.

Bach DH, Zhang W & Sood AK.

Chromosomal instability in tumor initiation and development.

Cancer Res (2019) 79:3995-4002.

Divakaran S et al.

Diagnostic accuracy of advanced imaging in cardiac sarcoidosis.

Circ Cardiovasc Imaging (2019) 12:e008975.

Xie W et al.

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.

Proc Natl Acad Sci U S A (2019) 116:11946-11955.

Bayraktar R, Bertilaccio MTS & Calin GA.

The interaction between two worlds: microRNAs and Toll-Like Receptors.

Front Immunol (2019) 10:1053.

Zheng L et al.

Hatchet ribozyme structure and implications for cleavage mechanism.

Proc Natl Acad Sci U S A (2019) 116:10783-10791.

Zelniker TA et al.

Biomarker of collagen turnover (C-terminal telopeptide) and prognosis in patients with non-ST-elevation acute coronary syndromes.

J Am Heart Assoc (2019) 8:e011444.

Koupenova M et al.

The role of platelets in mediating a response to human influenza infection.

Nat Commun (2019) 10:1780.

Ma S et al.

GnRH-R-targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition.

Mol Cancer Ther (2019) 18:969-979.

Shah R, Murthy V & Freedman JE.

Nuts, cardiovascular health, and diabetes.

Circ Res (2019) 124:825-826.

Roh JD et al.

Activin type II receptor signaling in cardiac aging and heart failure.

Sci Transl Med (2019) 11:482.

Ko D et al.

Proteomics profiling and risk of new-onset atrial fibrillation: Framingham Heart Study.

J Am Heart Assoc (2019) 8:e010976.

Mazzu YZ et al.

miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFbeta, and Wnt signaling.

Sci Rep (2019) 9:3197.

Grani C et al.

Comparison of myocardial fibrosis quantification methods by cardiovascular magnetic resonance imaging for risk stratification of patients with suspected myocarditis.

J Cardiovasc Magn Reson (2019) 21:14.

Liu B et al.

Interplay between miRNAs and host genes and their role in cancer.

Brief Funct Genomics (2018) 18:255-266.

Bei Y et al.

BMC Med (2019) 17:42.

Carrero I et al.

Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments.

Oncogene (2019) 38:3551-3568.

Usmani SM et al.

HIV-1 balances the fitness costs and benefits of disrupting the host cell actin cytoskeleton early after mucosal transmission.

Cell Host Microbe (2019) 25:73-86.e5.

LaFargue CJ et al.

Exploring and comparing adverse events between PARP inhibitors.

Lancet Oncol (2019) 20:e15-e28.

2018

Shah RV et al.

Proteins altered by surgical weight loss highlight biomarkers of insulin resistance in the community.

Arterioscler Thromb Vasc Biol (2019) 39:107-115.

Cortez MA et al.

Role of miRNAs in immune responses and immunotherapy in cancer.

Genes Chromosomes Cancer (2019) 58:244-253.
Related Pathway

Jia N et al.

Type III-A CRISPR-Cas Csm complexes: Assembly, periodic RNA cleavage, DNase activity regulation, and autoimmunity.

Mol Cell (2019) 73:264-277.e5.

Ge XA & Hunter CP.

Efficient homologous recombination in mice using long single stranded DNA and CRISPR Cas9 nickase.

G3 (2019) 9:281-286.

Chen B et al.

Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag.

Nat Commun (2018) 9:5065.

Zhou S et al.

Chronic Platelet-derived Growth Factor Receptor signaling exerts control over initiation of protein translation in glioma.

Life Sci Alliance (2018) 1:e201800029.
Related Pathway

Vita T et al.

Comparing CMR mapping methods and myocardial patterns toward heart failure outcomes in nonischemic dilated cardiomyopathy.

JACC Cardiovasc Imaging (2019) 12:1659-1669.

Villar-Prados A et al.

Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4.

Mol Cancer Ther (2019) 18:421-436.

Suryawanshi H et al.

A single-cell survey of the human first-trimester placenta and decidua.

Sci Adv (2018) 4:eaau4788.

Wei S et al.

Rapid preimplantation genetic screening using a handheld, nanopore-based DNA sequencer.

Fertil Steril (2018) 110:910-916.e2.

Hisamatsu T et al.

PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer.

Mol Cancer Ther (2019) 18:162-172.

Lu Y et al.

miR-205 regulates basal cell identity and stem cell regenerative potential during mammary reconstitution.

Stem Cells (2018) 36:1875-1889.

Shen P et al.

Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling.

Mol Oncol (2018) 12:1856-1870.

Monroig-Bosque PDC et al.

OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.

Sci Rep (2018) 8:13106.

Roy S et al.

microRNA 193a-5p regulates levels of Nucleolar- and Spindle-associated Protein 1 to suppress hepatocarcinogenesis.

Gastroenterology (2018) 155:1951-1966.e26.

Onuchic V et al.

Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci.

Science (2018) 361:1354.

Jun HJ et al.

A PDGFRalpha-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.

Nat Commun (2018) 9:3116.
Related Pathway

Gharpure KM et al.

FABP4 as a key determinant of metastatic potential of ovarian cancer.

Nat Commun (2018) 9:2923.
Related Pathway

Umamaheswaran S et al.

Stress, inflammation, and eicosanoids: an emerging perspective.

Cancer Metastasis Rev (2018) 37:203-211.

Moustafa AA et al.

MicroRNAs in prostate cancer: From function to biomarker discovery.

Exp Biol Med (2018) 243:817-825.

Badawi M et al.

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128.

Oncotarget (2018) 9:26032-26045.

Lyons YA et al.

Immune cell profiling in cancer: Molecular approaches to cell-specific identification.

NPJ Precis Oncol (2017) 1:26.

Yeung TL et al.

Systematic identification of druggable epithelial-stromal crosstalk signaling networks in ovarian cancer.

J Natl Cancer Inst (2019) 111:272-282.

Gyorgy B et al.

CRISPR/Cas9 mediated disruption of the Swedish APP allele as a therapeutic approach for early-onset Alzheimer’s disease.

Mol Ther Nucleic Acids (2018) 11:429-440.

Quinn JF.

Lost in translation? Finding our way to effective Alzheimer’s Disease therapies.

J Alzheimers Dis (2018) 64:S33-S39.

Staerk L et al.

Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: Cohort study based on longitudinal data from the Framingham Heart Study.

BMJ (2018) 361:k1453.

Marangoni F et al.

Tumor tolerance-promoting function of regulatory T cells is optimized by CD28, but strictly dependent on calcineurin.

J Immunol (2018) 200:3647-3661.

Smith AS et al.

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

Proc Natl Acad Sci USA (2018) 115:E4377-E4385.

Sardana M et al.

Association of left atrial function index with atrial fibrillation and cardiovascular disease: the Framingham offspring study.

J Am Heart Assoc (2018) 7:7.

Shah MY et al.

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

Genome Res (2018) 28:432-447.

Andersen MS et al.

A novel implementation of magnetic levitation to quantify leukocyte size, morphology, and magnetic properties to identify patients with sepsis.

Shock (2019) 51:147-152.

Wei S, Weiss ZR & Williams Z.

Rapid multiplex small DNA sequencing on the MinION Nanopore sequencing platform.

G3 (Bethesda) (2018) 8:1649-1657.

Rodriguez Cetina Biefer H et al.

Mast cells regulate CD4(+) T-cell differentiation in the absence of antigen presentation.

J Allergy Clin Immunol (2018) 142:1894-1908.e7.

Velazquez-Torres G et al.

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.

Nat Commun (2018) 9:461.

Viswanath P et al.

2-Hydroxyglutarate-mediated autophagy of the Endoplasmic Reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas.

Cancer Res (2018) 78:2290-2304.

Koupenova M et al.

Circulating platelets as mediators of immunity, inflammation, and thrombosis.

Circ Res (2018) 122:337-351.
Related Pathway

Hulsmans M et al.

Cardiac macrophages promote diastolic dysfunction.

J Exp Med (2018) 215:423-440.
Related Pathway

2017

McKenzie JA et al.

The effect of topoisomerase I inhibitors on the efficacy of T-cell-based cancer immunotherapy.

J Natl Cancer Inst (2018) 110:777-786.

Kanlikilicer P et al.

Therapeutic targeting of AXL receptor tyrosine kinase inhibits tumor growth and intraperitoneal metastasis in ovarian cancer models.

Mol Ther Nucleic Acids (2017) 9:251-262.

Soni A et al.

Study protocol for Smartphone Monitoring for Atrial fibrillation in Real-Time in India (SMART-India): a community-based screening and referral programme.

BMJ Open (2017) 7:e017668.

Boussiotis VA & Charest A.

Immunotherapies for malignant glioma.

Oncogene (2018) 37:1121-1141.

Noh K et al.

Differential effects of EGFL6 on tumor versus wound angiogenesis.

Cell Rep (2017) 21:2785-2795.

Lu Y et al.

MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels.

Cancer Res (2018) 78:64-74.

Vannini I et al.

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Nat Commun (2017) 8:1801.
Related Pathway

Singh PB et al.

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.

J Exp Med (2017) 214:3627-3643.

Ren A, Micura R & Patel DJ.

Structure-based mechanistic insights into catalysis by small self-cleaving ribozymes.

Curr Opin Chem Biol (2017) 41:71-83.

Zheng L et al.

Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme.

Nat Commun (2017) 8:1180.

Bhakta NR et al.

IFN-stimulated gene expression, type 2 inflammation, and endoplasmic reticulum stress in asthma.

Am J Respir Crit Care Med (2018) 197:313-324.

Mitamura T et al.

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).

Oncogene (2018) 37:722-731.
Related Pathway

Piao X et al.

Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ.

RNA (2018) 24:67-76.

Xiao J et al.

miR-31a-5p promotes postnatal cardiomyocyte proliferation by targeting RhoBTB1.

Exp Mol Med (2017) 49:e386.

Gerstberger S et al.

The conserved RNA exonuclease Rexo5 is required for 3′ end maturation of 28S rRNA, 5S rRNA, and snoRNAs.

Cell Rep (2017) 21:758-772.

Lu Y et al.

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/beta-catenin signaling.

Nat Med (2017) 23:1331-1341.

Grinberg YY, Zitzow LA & Kraig RP.

Intranasally administered IGF-1 inhibits spreading depression in vivo.

Brain Res (2017) 1677:47-57.

Shen P et al.

To Wnt or lose: The missing non-coding linc in colorectal cancer.

Int J Mol Sci (2017) 18:9.
Related Pathway

Rodriguez-Aguayo C et al.

Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.

Cell Discov (2017) 3:17029.

Dalton HJ et al.

Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression.

Clin Cancer Res (2017) 23:7034-7046.

Fleming ND et al.

Phase II trial of bevacizumab with dose-dense paclitaxel as first-line treatment in patients with advanced ovarian cancer.

Gynecol Oncol (2017) 147:41-46.

August P & Suthanthiran M.

Sex and kidney transplantation: Why can’t a woman be more like a man?

J Am Soc Nephrol (2017) 28:2829-2831.

Sardana M et al.

Clinical and echocardiographic correlates of Left Atrial Function Index: the Framingham offspring study.

J Am Soc Echocardiogr (2017) 30:904-912.e2.

Fabris L & Calin GA.

Understanding the genomic ultraconservations: T-UCRs and cancer.

Int Rev Cell Mol Biol (2017) 333:159-172.

Denizli M et al.

Chitosan nanoparticles for miRNA delivery.

Methods Mol Biol (2017) 1632:219-230.

Sarkar S et al.

PRKCI promotes immune suppression in ovarian cancer.

Genes Dev (2017) 31:1109-1121.

Montoya MM et al.

A distinct inhibitory function for miR-18a in Th17 cell differentiation.

J Immunol (2017) 199:559-569.

Farmer DT et al.

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.

Development (2017) 144:2517-2528.

Aldrugh S et al.

Atrial fibrillation, cognition and dementia: A review.

J Cardiovasc Electrophysiol (2017) 28:958-965.

Li J et al.

miR-29b contributes to multiple types of muscle atrophy.

Nat Commun (2017) 8:15201.

Rigoutsos I et al.

N-BLR, a primate-specific non-coding transcript, leads to colorectal cancer invasion and migration.

Genome Biol (2017) 18:98.

Farmer DT et al.

miR-205 is a critical regulator of lacrimal gland development.

Dev Biol (2017) 427:12-20.

Nikan M et al.

Synthesis and evaluation of parenchymal retention and efficacy of a metabolically stable O-phosphocholine-N-docosahexaenoyl-l-serine siRNA conjugate in mouse brain.

Bioconjug Chem (2017) 28:1758-1766.

Montoya MM & Ansel KM.

Small RNA transfection in primary human Th17 cells by next generation electroporation.

J Vis Exp (2017) 122:e55546.

Camarda R, Williams J & Goga A.

In vivo reprogramming of cancer metabolism by MYC.

Front Cell Dev Biol (2017) 5:35.

Rabinowicz N et al.

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer.

Oncotarget (2017) 8:27380-27392.

Roh J, Houstis N & Rosenzweig A.

Why don’t we have proven treatments for HFpEF?

Circ Res (2017) 120:1243-1245.

Putman TE et al.

WikiGenomes: an open web application for community consumption and curation of gene annotation data in Wikidata.

Database (Oxford) (2017) 2017:1.

Soni A et al.

RAHI-SATHI Indo-U.S. collaboration: The evolution of a trainee-led twinning model in global health into a multidisciplinary collaborative program.

Glob Health Sci Pract (2017) 5:152-163.

Wagner MJ et al.

Preclinical mammalian safety studies of EPHARNA (DOPC nanoliposomal EphA2-targeted siRNA).

Mol Cancer Ther (2017) 16:1114-1123.

Shi J et al.

miR-17-3p contributes to exercise-induced cardiac growth and protects against myocardial ischemia-reperfusion injury.

Theranostics (2017) 7:664-676.

Khvorova A & Watts JK.

The chemical evolution of oligonucleotide therapies of clinical utility.

Nat Biotechnol (2017) 35:238-248.

Yeo AT & Charest A.

Immune checkpoint blockade biology in mouse models of glioblastoma.

J Cell Biochem (2017) 118:2516-2527.

Anderton B et al.

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.

EMBO Rep (2017) 18:569-585.

Gladek I et al.

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.

Genes Chromosomes Cancer (2017) 56:439-452.

Modi A et al.

Validation of two point-of-care tests against standard lab measures of NO in saliva and in serum.

Nitric Oxide (2017) 64:16-21.

Heydari B, Harris WS & Kwong RY.

Response by Heydari et al to letter regarding article, “Effect of omega-3 acid ethyl esters on left ventricular remodeling after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial”.

Circulation (2017) 135:e13-e14.

2016

Krzeszinski JY et al.

Lipid osteoclastokines regulate breast cancer bone metastasis.

Endocrinology (2017) 158:477-489.

Van Roosbroeck K et al.

Combining anti-miR-155 with chemotherapy for the treatment of lung cancers.

Clin Cancer Res (2017) 23:2891-2904.

Moustafa AA et al.

Identification of microRNA signature and potential pathway targets in prostate cancer.

Exp Biol Med (Maywood) (2017) 242:536-546.

Pi F et al.

RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery.

Nanomedicine (2017) 13:1183-1193.

Previs RA et al.

The rise of genomic profiling in ovarian cancer.

Expert Rev Mol Diagn (2016) 16:1337-1351.

Yang L et al.

Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth.

Cell Metab (2016) 24:685-700.

Hatakeyama H et al.

Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers.

Cell Rep (2016) 17:1621-1631.

Shah R, Pico AR & Freedman JE.

Translational epidemiology: Entering a brave new world of team science.

Circ Res (2016) 119:1060-1062.

Ohtsuka M et al.

H19 noncoding RNA, an independent prognostic factor, regulates essential Rb-E2F and CDK8-beta-catenin signaling in colorectal cancer.

EBioMedicine (2016) 13:113-124.

Mangala LS et al.

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

JCI Insight (2016) 1:e87754.

Giza DE et al.

Cellular and viral microRNAs in sepsis: Mechanisms of action and clinical applications.

Cell Death Differ (2016) 23:1906-1918.
Related Pathway

Soni A et al.

High burden of unrecognized atrial fibrillation in rural india: An innovative community-based cross-sectional screening program.

JMIR Public Health Surveill (2016) 2:e159.

Tao L et al.

Crucial role of miR-433 in regulating cardiac fibrosis.

Theranostics (2016) 6:2068-2083.

Zhou J et al.

A novel compound ARN-3236 inhibits salt-inducible kinase 2 and sensitizes ovarian cancer cell lines and xenografts to paclitaxel.

Clin Cancer Res (2017) 23:1945-1954.

Huang Y et al.

Anti-tumor and anti-angiogenic effects of aspirin-PC in ovarian cancer.

Mol Cancer Ther (2016) 15:2894-2904.

Ciccone M & Calin GA.

MicroRNAs in chronic lymphocytic leukemia: An old disease with new genetic insights.

MicroRNA (2016) 5:106-112.
Related Pathway

Sardana M et al.

Association of left atrial function index with late atrial fibrillation recurrence after catheter ablation.

J Cardiovasc Electrophysiol (2016) 27:1411-1419.

Harjes U et al.

Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4.

Oncogene (2017) 36:912-921.

Walkey AJ et al.

Practice patterns and outcomes associated with use of anticoagulation among patients with atrial fibrillation during sepsis.

JAMA Cardiol (2016) 1:682-90.

Miranda F et al.

Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche.

Cancer Cell (2016) 30:273-289.

Wang JH et al.

Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug.

BMC Cancer (2016) 16:524.

Anfossi S & Calin GA.

Hodgkin lymphoma cells have a specific long noncoding RNA expression pattern.

Am J Pathol (2016) 186:2251-3.

Zhao Z et al.

An arginine finger regulates the sequential action of asymmetrical hexameric ATPase in the double-stranded DNA translocation motor.

Mol Cell Biol (2016) 36:2514-23.

Gao P et al.

Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition.

Cell Res (2016) 26:901-13.

Bezzerides VJ et al.

CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury.

JCI Insight (2016) 1:9.

Ren A et al.

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.

Nat Chem Biol (2016) 12:702-8.

Parasramka MA & Patel T.

Long non-coding RNA regulation of liver cancer stem cell self-renewal offers new therapeutic targeting opportunities.

Stem Cell Investig (2016) 3:1.

Henninger N et al.

Atrial fibrillation is associated with a worse 90-day outcome than other cardioembolic stroke subtypes.

Stroke (2016) 47:1486-92.

Chaluvally-Raghavan P et al.

Direct upregulation of STAT3 by microRNA-551b-3p deregulates growth and metastasis of ovarian cancer.

Cell Rep (2016) 15:1493-504.

Clarke D et al.

Identifying allosteric hotspots with dynamics: Application to inter- and intra-species conservation.

Structure (2016) 24:826-37.

Haemmerle M et al.

FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.

J Clin Invest (2016) 126:1885-96.

Yan KK et al.

Cross-disciplinary network comparison: Matchmaking between hairballs.

Cell Syst (2016) 2:147-157.

Ciccone M & Calin GA.

MicroRNAs in myeloid hematological malignancies.

Curr Genomics (2015) 16:336-48.

Pan Y et al.

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer.

Oncotarget (2016) 7:25930-48.

Putman TE et al.

Centralizing content and distributing labor: a community model for curating the very long tail of microbial genomes.

Database (Oxford) (2016) 2016:baw028.

Huang J et al.

Dll4 inhibition plus aflibercept markedly reduces ovarian tumor growth.

Mol Cancer Ther (2016) 15:1344-52.

Burgstaller-Muehlbacher S et al.

Wikidata as a semantic framework for the Gene Wiki initiative.

Database (Oxford) (2016) 2016:baw015.

Rytelewski M et al.

Reciprocal positive selection for weakness – preventing olaparib resistance by inhibiting BRCA2.

Oncotarget (2016) 7:20825-39.

Olivieri M et al.

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.

Oncotarget (2016) 7:20636-54.

Mora-Castilla S et al.

Miniaturization technologies for efficient single-cell library preparation for next-generation sequencing.

J Lab Autom (2016) 21:557-67.

Kundu A et al.

Relation of atrial fibrillation in acute myocardial infarction to in-hospital complications and early hospital readmission.

Am J Cardiol (2016) 117:1213-8.

Redis RS et al.

Allele-specific reprogramming of cancer metabolism by the long non-coding RNA CCAT2.

Mol Cell (2016) 61:520-34.

Pua HH et al.

MicroRNAs 24 and 27 suppress allergic inflammation and target a network of regulators of T Helper 2 cell-associated cytokine production.

Immunity (2016) 44:821-32.

Hansen JM, Coleman RL & Sood AK.

Targeting the tumour microenvironment in ovarian cancer.

Eur J Cancer (2016) 56:131-43.

Harmanci A & Gerstein M.

Quantification of private information leakage from phenotype-genotype data: linking attacks.

Nat Methods (2016) 13:251-6.

Guo P et al.

Biological nanomotors with a revolution, linear, or rotation motion mechanism.

Microbiol Mol Biol Rev (2016) 80:161-86.

Mitamura T, Gourley C & Sood AK.

Prediction and failure of anti-angiogenesis escape.

Gynecol Oncol (2016) 141:80-5.

Neophytou AM et al.

Air pollution and lung function in minority youth with asthma in the GALA II (Genes-environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) studies.

Am J Respir Crit Care Med (2016) 193:1271-80.

McManus DD et al.

Reliability of predicting early hospital readmission after discharge for an acute coronary syndrome using claims-based data.

Am J Cardiol (2016) 117:501-7.

2015

Ren A et al.

Structural and dynamic basis for low-affinity, high-selectivity binding of L-glutamine by the glutamine riboswitch.

Cell Rep (2015) 13:1800-13.

Askenase PW et al.

A subset of AID-dependent B-1a cells initiates hypersensitivity and pneumococcal pneumonia resistance.

Ann N Y Acad Sci (2015) 1362:200-14.

Alterman JF et al.

Hydrophobically modified siRNAs silence Huntingtin mRNA in primary neurons and mouse brain.

Mol Ther Nucleic Acids (2015) 4:e266.

Kalani MY et al.

Rare variants in cardiomyopathy genes associated with stress-induced cardiomyopathy.

Neurosurgery (2016) 78:835-43.

Shaikh AY et al.

Addition of B-type natriuretic peptide to existing clinical risk scores enhances identification of patients at risk for atrial fibrillation recurrence after pulmonary vein isolation.

Crit Pathw Cardiol (2015) 14:157-65.

Previs RA et al.

Dual metronomic chemotherapy with nab-paclitaxel and topotecan has potent antiangiogenic activity in ovarian cancer.

Mol Cancer Ther (2015) 14:2677-86.

Bucur O et al.

An updated h-index measures both the primary and total scientific output of a researcher.

Discoveries (2015) 3:3.

Wei S & Williams Z.

Rapid short-read sequencing and aneuploidy detection using MinION nanopore technology.

Genetics (2016) 202:37-44.

Pradeep S et al.

Erythropoietin stimulates tumor growth via EphB4.

Cancer Cell (2015) 28:610-22.

Kosutic M et al.

A mini-twister variant and impact of residues/cations on the phosphodiester cleavage of this ribozyme class.

Angew Chem Int Ed Engl (2015) 54:15128-33.

Yamamoto N et al.

Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: Evidence of a subpopulation of protective anti-pneumococcal B1a cells.

Immunology (2016) 147:97-113.

Giza DE, Vasilescu C & Calin GA.

Key principles of miRNA involvement in human diseases.

Discoveries (Craiova) (2014) 2:e34.

Ohtsuka M et al.

MicroRNA processing and human cancer.

J Clin Med (2015) 4:1651-67.

Ferrajoli A et al.

Epstein-Barr virus microRNAs are expressed in patients with chronic lymphocytic leukemia and correlate with overall survival.

EBioMedicine (2015) 2:572-82.

Nagaraja AS et al.

Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis.

Oncogene (2016) 35:2390-7.

Matsuo K et al.

Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma.

Eur J Cancer (2015) 51:1978-88.

Reyes-Gonzalez JM et al.

Targeting c-MYC in platinum-resistant ovarian cancer.

Mol Cancer Ther (2015) 14:2260-9.

Ong WQ et al.

Heavy water: a simple solution to increasing the brightness of fluorescent proteins in super-resolution imaging.

Chem Commun (Camb) (2015) 51:13451-3.

Gharpure KM et al.

Nanotechnology: Future of oncotherapy.

Clin Cancer Res (2015) 21:3121-30.

Zhang S et al.

CDK5 regulates paclitaxel sensitivity in ovarian cancer cells by modulating AKT activation, p21Cip1- and p27Kip1-mediated G1 cell cycle arrest and apoptosis.

PLoS ONE (2015) 10:e0131833.

Ren A, Rajashankar KR & Patel DJ.

Global RNA fold and molecular recognition for a pfl riboswitch bound to ZMP, a master regulator of one-carbon metabolism.

Structure (2015) 23:1375-81.

Aslan B et al.

The ZNF304-integrin axis protects against anoikis in cancer.

Nat Commun (2015) 6:7351.

Kwong RY et al.

Characterization of cardiac amyloidosis by atrial late gadolinium enhancement using contrast-enhanced cardiac Magnetic Resonance Imaging and correlation with left atrial conduit and contractile function.

Am J Cardiol (2015) 116:622-9.

Szabo L et al.

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.

Genome Biol (2015) 16:126.

Boettcher M & McManus MT.

Choosing the right tool for the job: RNAi, TALEN, or CRISPR.

Mol Cell (2015) 58:575-85.

Li X et al.

Lowering the quantification limit of the QubitTM RNA HS assay using RNA spike-in.

BMC Mol Biol (2015) 16:9.

Li K et al.

Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.

Circ Res (2015) 117:e1-e11.
Related Pathway

Wong HK et al.

The Cancer Genome Atlas analysis predicts microRNA for targeting cancer growth and vascularization in glioblastoma.

Mol Ther (2015) 23:1234-47.
Related Pathway

Miyake TM et al.

XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A.

Clin Cancer Res (2015) 21:3286-97.
Related Pathway

Liu X et al.

miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.

Cell Metab (2015) 21:584-95.
Related Pathway

Schwarzenbacher D et al.

Low spinophilin expression enhances aggressive biological behavior of breast cancer.

Oncotarget (2015) 6:11191-202.

Gilder AS et al.

Soluble Urokinase Receptor is released selectively by glioblastoma cells that express Epidermal Growth Factor Receptor variant III and promotes tumor cell migration and invasion.

J Biol Chem (2015) 290:14798-809.

Thanapprapa D Sr et al.

PTEN expression as a predictor of response to focal adhesion kinase inhibition in uterine cancer.

Mol Cancer Ther (2015) 14:1466-1475.

Ren A et al.

Structural basis for molecular discrimination by a 3′,3′-cGAMP sensing riboswitch.

Cell Rep (2015) 11:1-12.

Ling H et al.

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.

Gut (2016) 65:977-989.

Neilan TG et al.

Late gadolinium enhancement among survivors of sudden cardiac arrest.

JACC Cardiovasc Imaging (2015) 8:414-423.

Huan T et al.

Genome-wide identification of microRNA expression Quantitative Trait Loci.

Nat Commun (2015) 6:6601.

Martinez GJ et al.

The transcription factor NFAT promotes exhaustion of activated CD8(+) T cells.

Immunity (2015) 42:265-78.

Wei X, Liu X & Rosenzweig A.

What do we know about the cardiac benefits of exercise?

Trends Cardiovasc Med (2015) 25:529-36.

Koupenova M et al.

Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors.

Arterioscler Thromb Vasc Biol (2015) 35:1030-7.

Cox JE et al.

Pan-viral-microRNA screening identifies interferon inhibition as a common function of diverse viruses.

Proc Natl Acad Sci U S A (2015) 112:1856-61.

Ling H et al.

Junk DNA and the long non-coding RNA Twist in cancer genetics.

Oncogene (2015) 34:5003-11.

2014

Bodhankar S et al.

Regulatory CD8(+)CD122 (+) T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting B-cells.

Metab Brain Dis (2015) 30:911-924.

Yao C et al.

Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.

Circulation (2015) 131:536-49.

Pusic AD et al.

Spreading depression transiently disrupts myelin via interferon-gamma signaling.

Exp Neurol (2015) 264:43-54.

Yang X et al.

New ways to successfully target tumor vasculature in ovarian cancer.

Curr Opin Obstet Gynecol (2015) 27:58-65.

Koupenova M & Freedman JE.

Platelets: the unsung hero of the immune response.

J Thromb Haemost (2015) 13:268-70.

Bottsford-Miller J et al.

Differential platelet levels affect response to taxane-based therapy in ovarian cancer.

Clin Cancer Res (2015) 21:602-10.

Dotson AL et al.

Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke.

J Neuroimmunol (2015) 278:289-98.

Wen Y et al.

Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer.

Clin Cancer Res (2015) 21:448-59.

Ren A et al.

In-line alignment and Mg(2)(+) coordination at the cleavage site of the env22 twister ribozyme.

Nat Commun (2014) 5:5534.

Previs RA et al.

Molecular pathways: Translational and therapeutic implications of the Notch signaling pathway in cancer.

Clin Cancer Res (2015) 21:955-61.

van den Beucken T et al.

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

Nat Commun (2014) 5:5203.
Related Pathway

Leung CS et al.

Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.

Nat Commun (2014) 5:5092.
Related Pathway

del C. Monroig P et al.

Small molecule compounds targeting miRNAs for cancer therapy.

Adv Drug Deliv Rev (2015) 81:104-16.

Gonzalez-Villasana V et al.

Bisphosphonates inhibit stellate cell activity and enhance antitumor effects of nanoparticle albumin-bound paclitaxel in pancreatic ductal adenocarcinoma.

Mol Cancer Ther (2014) 13:2583-94.

Quesenberry PJ, Goldberg LR & Dooner MS.

Concise reviews: A stem cell apostasy: a tale of four H words.

Stem Cells (2015) 33:15-20.

Mata IF et al.

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.

JAMA Neurol (2014) 71:1405-12.

Han C et al.

The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression.

Cell Rep (2014) 8:1447-60.
Related Pathway

Maguire CA et al.

Gene therapy for the nervous system: Challenges and new strategies.

Neurotherapeutics (2014) 11:817-39.

Berindan-Neagoe I et al.

MicroRNAome genome: a treasure for cancer diagnosis and therapy.

CA Cancer J Clin (2014) 64:311-36.

Ren A & Patel DJ.

c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.

Nat Chem Biol (2014) 10:780-6.

Pradeep S et al.

Hematogenous metastasis of ovarian cancer: Rethinking mode of spread.

Cancer Cell (2014) 26:77-91.

Davis AN, Afshar-Kharghan V & Sood AK.

Platelet effects on ovarian cancer.

Semin Oncol (2014) 41:378-84.

Murphy SJ et al.

Sex differences in microRNA expression during development in rat cortex.

Neurochem Int (2014) 77:24-32.

Wu SY et al.

RNAi therapies: Drugging the undruggable.

Sci Transl Med (2014) 6:240ps7.

Nery FC et al.

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia.

J Neurosci Methods (2014) 232:181-8.

Bauer CA et al.

Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction.

J Clin Invest (2014) 124:2425-40.

Jiang H et al.

Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2.

Cancer Immunol Res (2014) 2:789-99.

Yang L et al.

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer.

Mol Syst Biol (2014) 10:728.
Related Pathway

Freedman JE.

Inherited dysfunctional nitric oxide signaling and the pathobiology of atherothrombotic disease.

Circ Res (2014) 114:1372-3.

Tucker SL et al.

Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer.

Clin Cancer Res (2014) 20:3280-8.

Gharpure KM et al.

Metronomic Docetaxel in PRINT Nanoparticles and EZH2 Silencing Have Synergistic Antitumor Effect in Ovarian Cancer.

Mol Cancer Ther (2014) 13:1750-7.

Hu W et al.

Notch3 pathway alterations in ovarian cancer.

Cancer Res (2014) 74:3282-93.
Related Pathway

Pusic KM et al.

Spreading depression requires microglia and is decreased by their M2a polarization from environmental enrichment.

Glia (2014) 62:1176-94.

Patel T & Harnois D.

Assessment of response to therapy in hepatocellular carcinoma.

Ann Med (2014) 46:130-7.

Zhang H et al.

Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.

Breast Cancer Res (2014) 16:R36.

Cholerton BA et al.

Evaluation of mild cognitive impairment subtypes in Parkinson’s disease.

Mov Disord (2014) 29:756-64.

Jiang H et al.

Quantitatively controlling expression of miR-17~92 determines colon tumor progression in a mouse tumor model.

Am J Pathol (2014) 184:1355-68.

Wu SY et al.

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.

Nat Commun (2014) 5:3459.

Cho MS et al.

Autocrine effects of tumor-derived complement.

Cell Rep (2014) 6:1085-95.

Lusardi TA et al.

MicroRNA responses to Focal Cerebral Ischemia in male and female mouse brain.

Front Mol Neurosci (2014) 7:11.

Dalton HJ et al.

Monocyte subpopulations in angiogenesis.

Cancer Res (2014) 74:1287-93.

Morey R & Laurent LC.

Getting off the ground state: X chromosome inactivation knocks down barriers to differentiation.

Cell Stem Cell (2014) 14:131-2.

Beaulieu LM et al.

Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans.

Arterioscler Thromb Vasc Biol (2014) 34:552-64.
Related Pathway

2013

Ngamruengphong S & Patel T.

Molecular evolution of genetic susceptibility to hepatocellular carcinoma.

Dig Dis Sci (2014) 59:986-91.

Yao C et al.

Sex- and age-interacting eQTLs in human complex diseases.

Hum Mol Genet (2014) 23:1947-56.

Jun HJ, Bronson RT & Charest A.

Inhibition of EGFR induces a c-MET-driven stem cell population in glioblastoma.

Stem Cells (2014) 32:338-48.

Aslan B et al.

Nanotechnology in cancer therapy.

J Drug Target (2013) 21:904-13.

Pecot CV et al.

Tumour angiogenesis regulation by the miR-200 family.

Nat Commun (2013) 4:2427.

Nishimura M et al.

Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment.

Cancer Discov (2013) 3:1302-15.

Saugstad JA.

MicroRNAs as effectors of brain function.

Stroke (2013) 44:S17-9.