Additional ERCC Research

2019

Yoneshiro T et al.

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

Nature (2019) 572:614-619.

Divakaran S et al.

Diagnostic accuracy of advanced imaging in cardiac sarcoidosis.

Circ Cardiovasc Imaging (2019) 12:e008975.

Bayraktar R, Bertilaccio MTS & Calin GA.

The interaction between two worlds: microRNAs and Toll-Like Receptors.

Front Immunol (2019) 10:1053.

Zheng L et al.

Hatchet ribozyme structure and implications for cleavage mechanism.

Proc Natl Acad Sci U S A (2019) 116:10783-10791.

Koupenova M et al.

The role of platelets in mediating a response to human influenza infection.

Nat Commun (2019) 10:1780.

Ma S et al.

GnRH-R-targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition.

Mol Cancer Ther (2019) 18:969-979.

Shah R, Murthy V & Freedman JE.

Nuts, cardiovascular health, and diabetes.

Circ Res (2019) 124:825-826.

Ko D et al.

Proteomics profiling and risk of new-onset atrial fibrillation: Framingham Heart Study.

J Am Heart Assoc (2019) 8:e010976.

Mazzu YZ et al.

miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFbeta, and Wnt signaling.

Sci Rep (2019) 9:3197.

Bei Y et al.

Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury.

BMC Med (2019) 17:42.

Usmani SM et al.

HIV-1 balances the fitness costs and benefits of disrupting the host cell actin cytoskeleton early after mucosal transmission.

Cell Host Microbe (2019) 25:73-86.e5.

2018

Shah RV et al.

Proteins altered by surgical weight loss highlight biomarkers of insulin resistance in the community.

Arterioscler Thromb Vasc Biol (2019) 39:107-115.

Cortez MA et al.

Role of miRNAs in immune responses and immunotherapy in cancer.

Genes Chromosomes Cancer (2019) 58:244-253.
Related Pathway

Jia N et al.

Type III-A CRISPR-Cas Csm complexes: Assembly, periodic RNA cleavage, DNase activity regulation, and autoimmunity.

Mol Cell (2019) 73:264-277.e5.

Ge XA & Hunter CP.

Efficient homologous recombination in mice using long single stranded DNA and CRISPR Cas9 nickase.

G3 (2019) 9:281-286.

Chen B et al.

Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag.

Nat Commun (2018) 9:5065.

Zhou S et al.

Chronic Platelet-derived Growth Factor Receptor signaling exerts control over initiation of protein translation in glioma.

Life Sci Alliance (2018) 1:e201800029.
Related Pathway

Vita T et al.

Comparing CMR mapping methods and myocardial patterns toward heart failure outcomes in nonischemic dilated cardiomyopathy.

JACC Cardiovasc Imaging (2019) 12:1659-1669.

Villar-Prados A et al.

Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4.

Mol Cancer Ther (2019) 18:421-436.

Suryawanshi H et al.

A single-cell survey of the human first-trimester placenta and decidua.

Sci Adv (2018) 4:eaau4788.

Wei S et al.

Rapid preimplantation genetic screening using a handheld, nanopore-based DNA sequencer.

Fertil Steril (2018) 110:910-916.e2.

Wei F et al.

Electric field-induced release and measurement liquid biopsy for noninvasive early lung cancer assessment.

J Mol Diagn (2018) 20:738-742.

Hisamatsu T et al.

PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer.

Mol Cancer Ther (2019) 18:162-172.

Lu Y et al.

miR-205 regulates basal cell identity and stem cell regenerative potential during mammary reconstitution.

Stem Cells (2018) 36:1875-1889.

Monroig-Bosque PDC et al.

OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.

Sci Rep (2018) 8:13106.

Roy S et al.

microRNA 193a-5p regulates levels of Nucleolar- and Spindle-associated Protein 1 to suppress hepatocarcinogenesis.

Gastroenterology (2018) 155:1951-1966.e26.

Onuchic V et al.

Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci.

Science (2018) 361:1354.

Jun HJ et al.

A PDGFRalpha-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.

Nat Commun (2018) 9:3116.
Related Pathway

Gharpure KM et al.

FABP4 as a key determinant of metastatic potential of ovarian cancer.

Nat Commun (2018) 9:2923.
Related Pathway

Umamaheswaran S et al.

Stress, inflammation, and eicosanoids: an emerging perspective.

Cancer Metastasis Rev (2018) 37:203-211.

Moustafa AA et al.

MicroRNAs in prostate cancer: From function to biomarker discovery.

Exp Biol Med (2018) 243:817-825.

Lyons YA et al.

Immune cell profiling in cancer: Molecular approaches to cell-specific identification.

NPJ Precis Oncol (2017) 1:26.

Gyorgy B et al.

CRISPR/Cas9 mediated disruption of the Swedish APP allele as a therapeutic approach for early-onset Alzheimer’s disease.

Mol Ther Nucleic Acids (2018) 11:429-440.

Quinn JF.

Lost in translation? Finding our way to effective Alzheimer’s Disease therapies.

J Alzheimers Dis (2018) 64:S33-S39.

Staerk L et al.

Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: Cohort study based on longitudinal data from the Framingham Heart Study.

BMJ (2018) 361:k1453.

Marangoni F et al.

Tumor tolerance-promoting function of regulatory T cells is optimized by CD28, but strictly dependent on calcineurin.

J Immunol (2018) 200:3647-3661.

Smith AS et al.

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

Proc Natl Acad Sci USA (2018) 115:E4377-E4385.

Sardana M et al.

Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: the Framingham Offspring Study.

J Am Heart Assoc (2018) 7.

Shah MY et al.

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

Genome Res (2018) 28:432-447.

Andersen MS et al.

A novel implementation of magnetic levitation to quantify leukocyte size, morphology, and magnetic properties to identify patients with sepsis.

Shock (2019) 51:147-152.

Wei S, Weiss ZR & Williams Z.

Rapid multiplex small DNA sequencing on the MinION Nanopore sequencing platform.

G3 (Bethesda) (2018) 8:1649-1657.

Rodriguez Cetina Biefer H et al.

Mast cells regulate CD4(+) T-cell differentiation in the absence of antigen presentation.

J Allergy Clin Immunol (2018) 142:1894-1908.e7.

Velazquez-Torres G et al.

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.

Nat Commun (2018) 9:461.

Viswanath P et al.

2-Hydroxyglutarate-mediated autophagy of the Endoplasmic Reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas.

Cancer Res (2018) 78:2290-2304.

Koupenova M et al.

Circulating platelets as mediators of immunity, inflammation, and thrombosis.

Circ Res (2018) 122:337-351.
Related Pathway

Hulsmans M et al.

Cardiac macrophages promote diastolic dysfunction.

J Exp Med (2018) 215:423-440.
Related Pathway

2017

McKenzie JA et al.

The effect of topoisomerase I inhibitors on the efficacy of T-cell-based cancer immunotherapy.

J Natl Cancer Inst (2018) 110:777-786.

Leung CS et al.

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.

J Clin Invest (2018) 128:589-606.
Related Pathway

Kanlikilicer P et al.

Therapeutic targeting of AXL receptor tyrosine kinase inhibits tumor growth and intraperitoneal metastasis in ovarian cancer models.

Mol Ther Nucleic Acids (2017) 9:251-262.

Soni A et al.

Study protocol for Smartphone Monitoring for Atrial fibrillation in Real-Time in India (SMART-India): a community-based screening and referral programme.

BMJ Open (2017) 7:e017668.

Boussiotis VA & Charest A.

Immunotherapies for malignant glioma.

Oncogene (2018) 37:1121-1141.

Noh K et al.

Differential effects of EGFL6 on tumor versus wound angiogenesis.

Cell Rep (2017) 21:2785-2795.

Vannini I et al.

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Nat Commun (2017) 8:1801.
Related Pathway

Lu Y et al.

MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels.

Cancer Res (2018) 78:64-74.

Singh PB et al.

MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.

J Exp Med (2017) 214:3627-3643.

Zheng L et al.

Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme.

Nat Commun (2017) 8:1180.

Bhakta NR et al.

IFN-stimulated gene expression, type 2 inflammation, and endoplasmic reticulum stress in asthma.

Am J Respir Crit Care Med (2018) 197:313-324.

Mitamura T et al.

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).

Oncogene (2018) 37:722-731.
Related Pathway

Piao X et al.

Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ.

RNA (2018) 24:67-76.

Xiao J et al.

miR-31a-5p promotes postnatal cardiomyocyte proliferation by targeting RhoBTB1.

Exp Mol Med (2017) 49:e386.

Gerstberger S et al.

The conserved RNA exonuclease Rexo5 is required for 3′ end maturation of 28S rRNA, 5S rRNA, and snoRNAs.

Cell Rep (2017) 21:758-772.

Grinberg YY, Zitzow LA & Kraig RP.

Intranasally administered IGF-1 inhibits spreading depression in vivo.

Brain Res (2017) 1677:47-57.

Shen P et al.

To Wnt or lose: The missing non-coding linc in colorectal cancer.

Int J Mol Sci (2017) 18:9.
Related Pathway

Rodriguez-Aguayo C et al.

Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.

Cell Discov (2017) 3:17029.

Dalton HJ et al.

Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression.

Clin Cancer Res (2017) 23:7034-7046.

Fleming ND et al.

Phase II trial of bevacizumab with dose-dense paclitaxel as first-line treatment in patients with advanced ovarian cancer.

Gynecol Oncol (2017) 147:41-46.

August P & Suthanthiran M.

Sex and kidney transplantation: Why can’t a woman be more like a man?

J Am Soc Nephrol (2017) 28:2829-2831.

Sardana M et al.

Clinical and echocardiographic correlates of Left Atrial Function Index: the Framingham offspring study.

J Am Soc Echocardiogr (2017) 30:904-912.e2.

Fabris L & Calin GA.

Understanding the genomic ultraconservations: T-UCRs and cancer.

Int Rev Cell Mol Biol (2017) 333:159-172.

Denizli M et al.

Chitosan nanoparticles for miRNA delivery.

Methods Mol Biol (2017) 1632:219-230.

Sarkar S et al.

PRKCI promotes immune suppression in ovarian cancer.

Genes Dev (2017) 31:1109-1121.

Montoya MM et al.

A distinct inhibitory function for miR-18a in Th17 cell differentiation.

J Immunol (2017) 199:559-569.

Farmer DT et al.

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.

Development (2017) 144:2517-2528.

Aldrugh S et al.

Atrial fibrillation, cognition and dementia: A review.

J Cardiovasc Electrophysiol (2017) 28:958-965.

Li J et al.

miR-29b contributes to multiple types of muscle atrophy.

Nat Commun (2017) 8:15201.

Rigoutsos I et al.

N-BLR, a primate-specific non-coding transcript, leads to colorectal cancer invasion and migration.

Genome Biol (2017) 18:98.

Farmer DT et al.

miR-205 is a critical regulator of lacrimal gland development.

Dev Biol (2017) 427:12-20.

Nikan M et al.

Synthesis and evaluation of parenchymal retention and efficacy of a metabolically stable O-phosphocholine-N-docosahexaenoyl-l-serine siRNA conjugate in mouse brain.

Bioconjug Chem (2017) 28:1758-1766.

Montoya MM & Ansel KM.

Small RNA transfection in primary human Th17 cells by next generation electroporation.

J Vis Exp (2017) 122:e55546.

Rabinowicz N et al.

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer.

Oncotarget (2017) 8:27380-27392.

Roh J, Houstis N & Rosenzweig A.

Why don’t we have proven treatments for HFpEF?

Circ Res (2017) 120:1243-1245.

Putman TE et al.

WikiGenomes: an open web application for community consumption and curation of gene annotation data in Wikidata.

Database (Oxford) (2017) 2017:1.

Soni A et al.

RAHI-SATHI Indo-U.S. collaboration: The evolution of a trainee-led twinning model in global health into a multidisciplinary collaborative program.

Glob Health Sci Pract (2017) 5:152-163.

Wagner MJ et al.

Preclinical mammalian safety studies of EPHARNA (DOPC nanoliposomal EphA2-targeted siRNA).

Mol Cancer Ther (2017) 16:1114-1123.

Shi J et al.

miR-17-3p contributes to exercise-induced cardiac growth and protects against myocardial ischemia-reperfusion injury.

Theranostics (2017) 7:664-676.

Khvorova A & Watts JK.

The chemical evolution of oligonucleotide therapies of clinical utility.

Nat Biotechnol (2017) 35:238-248.

Yeo AT & Charest A.

Immune checkpoint blockade biology in mouse models of glioblastoma.

J Cell Biochem (2017) 118:2516-2527.

Anderton B et al.

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.

EMBO Rep (2017) 18:569-585.

Gladek I et al.

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.

Genes Chromosomes Cancer (2017) 56:439-452.

Modi A et al.

Validation of two point-of-care tests against standard lab measures of NO in saliva and in serum.

Nitric Oxide (2017) 64:16-21.

Heydari B, Harris WS & Kwong RY.

Response by Heydari et al to letter regarding article, “Effect of omega-3 acid ethyl esters on left ventricular remodeling after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial”.

Circulation (2017) 135:e13-e14.

2016

Krzeszinski JY et al.

Lipid osteoclastokines regulate breast cancer bone metastasis.

Endocrinology (2017) 158:477-489.

Moustafa AA et al.

Identification of microRNA signature and potential pathway targets in prostate cancer.

Exp Biol Med (Maywood) (2017) 242:536-546.

Van Roosbroeck K et al.

Combining anti-miR-155 with chemotherapy for the treatment of lung cancers.

Clin Cancer Res (2017) 23:2891-2904.

Pi F et al.

RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery.

Nanomedicine (2017) 13:1183-1193.

Yang L et al.

Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth.

Cell Metab (2016) 24:685-700.

Previs RA et al.

The rise of genomic profiling in ovarian cancer.

Expert Rev Mol Diagn (2016) 16:1337-1351.

Hatakeyama H et al.

Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers.

Cell Rep (2016) 17:1621-1631.

Ohtsuka M et al.

H19 noncoding RNA, an independent prognostic factor, regulates essential Rb-E2F and CDK8-beta-catenin signaling in colorectal cancer.

EBioMedicine (2016) 13:113-124.

Shah R, Pico AR & Freedman JE.

Translational epidemiology: Entering a brave new world of team science.

Circ Res (2016) 119:1060-1062.

Mangala LS et al.

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

JCI Insight (2016) 1:e87754.

Giza DE et al.

Cellular and viral microRNAs in sepsis: Mechanisms of action and clinical applications.

Cell Death Differ (2016) 23:1906-1918.
Related Pathway

Soni A et al.

High burden of unrecognized atrial fibrillation in rural india: An innovative community-based cross-sectional screening program.

JMIR Public Health Surveill (2016) 2:e159.

Tao L et al.

Crucial role of miR-433 in regulating cardiac fibrosis.

Theranostics (2016) 6:2068-2083.

Zhou J et al.

A novel compound ARN-3236 inhibits salt-inducible kinase 2 and sensitizes ovarian cancer cell lines and xenografts to paclitaxel.

Clin Cancer Res (2017) 23:1945-1954.

Huang Y et al.

Anti-tumor and anti-angiogenic effects of aspirin-PC in ovarian cancer.

Mol Cancer Ther (2016) 15:2894-2904.

Ciccone M & Calin GA.

MicroRNAs in chronic lymphocytic leukemia: An old disease with new genetic insights.

MicroRNA (2016) 5:106-112.
Related Pathway

Sardana M et al.

Association of left atrial function index with late atrial fibrillation recurrence after catheter ablation.

J Cardiovasc Electrophysiol (2016) 27:1411-1419.

Harjes U et al.

Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4.

Oncogene (2017) 36:912-921.

Walkey AJ et al.

Practice patterns and outcomes associated with use of anticoagulation among patients with atrial fibrillation during sepsis.

JAMA Cardiol (2016) 1:682-90.

Miranda F et al.

Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche.

Cancer Cell (2016) 30:273-289.

Wang JH et al.

Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug.

BMC Cancer (2016) 16:524.

Anfossi S & Calin GA.

Hodgkin lymphoma cells have a specific long noncoding RNA expression pattern.

Am J Pathol (2016) 186:2251-3.

Zhao Z et al.

An arginine finger regulates the sequential action of asymmetrical hexameric ATPase in the double-stranded DNA translocation motor.

Mol Cell Biol (2016) 36:2514-23.

Gao P et al.

Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition.

Cell Res (2016) 26:901-13.

Bezzerides VJ et al.

CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury.

JCI Insight (2016) 1:9.

Ren A et al.

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.

Nat Chem Biol (2016) 12:702-8.

Parasramka MA & Patel T.

Long non-coding RNA regulation of liver cancer stem cell self-renewal offers new therapeutic targeting opportunities.

Stem Cell Investig (2016) 3:1.

Henninger N et al.

Atrial fibrillation is associated with a worse 90-day outcome than other cardioembolic stroke subtypes.

Stroke (2016) 47:1486-92.

Chaluvally-Raghavan P et al.

Direct upregulation of STAT3 by microRNA-551b-3p deregulates growth and metastasis of ovarian cancer.

Cell Rep (2016) 15:1493-504.
Therapeutics 

Clarke D et al.

Identifying allosteric hotspots with dynamics: Application to inter- and intra-species conservation.

Structure (2016) 24:826-37.

Haemmerle M et al.

FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.

J Clin Invest (2016) 126:1885-96.

Ciccone M & Calin GA.

MicroRNAs in myeloid hematological malignancies.

Curr Genomics (2015) 16:336-48.

Yan KK et al.

Cross-disciplinary network comparison: Matchmaking between hairballs.

Cell Syst (2016) 2:147-157.

Pan Y et al.

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer.

Oncotarget (2016) 7:25930-48.

Putman TE et al.

Centralizing content and distributing labor: a community model for curating the very long tail of microbial genomes.

Database (Oxford) (2016) 2016:baw028.

Huang J et al.

Dll4 inhibition plus aflibercept markedly reduces ovarian tumor growth.

Mol Cancer Ther (2016) 15:1344-52.

Burgstaller-Muehlbacher S et al.

Wikidata as a semantic framework for the Gene Wiki initiative.

Database (Oxford) (2016) 2016:baw015.

Rytelewski M et al.

Reciprocal positive selection for weakness – preventing olaparib resistance by inhibiting BRCA2.

Oncotarget (2016) 7:20825-39.

Olivieri M et al.

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.

Oncotarget (2016) 7:20636-54.

Mora-Castilla S et al.

Miniaturization technologies for efficient single-cell library preparation for next-generation sequencing.

J Lab Autom (2016) 21:557-67.

Kundu A et al.

Relation of atrial fibrillation in acute myocardial infarction to in-hospital complications and early hospital readmission.

Am J Cardiol (2016) 117:1213-8.

Redis RS et al.

Allele-specific reprogramming of cancer metabolism by the long non-coding RNA CCAT2.

Mol Cell (2016) 61:520-34.

Pua HH et al.

MicroRNAs 24 and 27 suppress allergic inflammation and target a network of regulators of T Helper 2 cell-associated cytokine production.

Immunity (2016) 44:821-32.

Hansen JM, Coleman RL & Sood AK.

Targeting the tumour microenvironment in ovarian cancer.

Eur J Cancer (2016) 56:131-43.

Harmanci A & Gerstein M.

Quantification of private information leakage from phenotype-genotype data: linking attacks.

Nat Methods (2016) 13:251-6.

Guo P et al.

Biological nanomotors with a revolution, linear, or rotation motion mechanism.

Microbiol Mol Biol Rev (2016) 80:161-86.

Mitamura T, Gourley C & Sood AK.

Prediction and failure of anti-angiogenesis escape.

Gynecol Oncol (2016) 141:80-5.

Neophytou AM et al.

Air pollution and lung function in minority youth with asthma in the GALA II (Genes-environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) studies.

Am J Respir Crit Care Med (2016) 193:1271-80.

McManus DD et al.

Reliability of predicting early hospital readmission after discharge for an acute coronary syndrome using claims-based data.

Am J Cardiol (2016) 117:501-7.

2015

Askenase PW et al.

A subset of AID-dependent B-1a cells initiates hypersensitivity and pneumococcal pneumonia resistance.

Ann N Y Acad Sci (2015) 1362:200-14.

Ren A et al.

Structural and dynamic basis for low-affinity, high-selectivity binding of L-glutamine by the glutamine riboswitch.

Cell Rep (2015) 13:1800-13.

Alterman JF et al.

Hydrophobically modified siRNAs silence Huntingtin mRNA in primary neurons and mouse brain.

Mol Ther Nucleic Acids (2015) 4:e266.

Kalani MY et al.

Rare variants in cardiomyopathy genes associated with stress-induced cardiomyopathy.

Neurosurgery (2016) 78:835-43.

Shaikh AY et al.

Addition of B-type natriuretic peptide to existing clinical risk scores enhances identification of patients at risk for atrial fibrillation recurrence after pulmonary vein isolation.

Crit Pathw Cardiol (2015) 14:157-65.

Previs RA et al.

Dual metronomic chemotherapy with nab-paclitaxel and topotecan has potent antiangiogenic activity in ovarian cancer.

Mol Cancer Ther (2015) 14:2677-86.

Bucur O et al.

An updated h-index measures both the primary and total scientific output of a researcher.

Discoveries (2015) 3:3.

Wei S & Williams Z.

Rapid short-read sequencing and aneuploidy detection using MinION nanopore technology.

Genetics (2016) 202:37-44.

Pradeep S et al.

Erythropoietin stimulates tumor growth via EphB4.

Cancer Cell (2015) 28:610-22.

Kosutic M et al.

A mini-twister variant and impact of residues/cations on the phosphodiester cleavage of this ribozyme class.

Angew Chem Int Ed Engl (2015) 54:15128-33.

Yamamoto N et al.

Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: Evidence of a subpopulation of protective anti-pneumococcal B1a cells.

Immunology (2016) 147:97-113.

Giza DE, Vasilescu C & Calin GA.

Key principles of miRNA involvement in human diseases.

Discoveries (Craiova) (2014) 2:e34.

Ohtsuka M et al.

MicroRNA processing and human cancer.

J Clin Med (2015) 4:1651-67.

Ferrajoli A et al.

Epstein-Barr virus microRNAs are expressed in patients with chronic lymphocytic leukemia and correlate with overall survival.

EBioMedicine (2015) 2:572-82.

Nagaraja AS et al.

Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis.

Oncogene (2016) 35:2390-7.

Reyes-Gonzalez JM et al.

Targeting c-MYC in platinum-resistant ovarian cancer.

Mol Cancer Ther (2015) 14:2260-9.

Ong WQ et al.

Heavy water: a simple solution to increasing the brightness of fluorescent proteins in super-resolution imaging.

Chem Commun (Camb) (2015) 51:13451-3.

Gharpure KM et al.

Nanotechnology: Future of oncotherapy.

Clin Cancer Res (2015) 21:3121-30.

Ren A, Rajashankar KR & Patel DJ.

Global RNA fold and molecular recognition for a pfl riboswitch bound to ZMP, a master regulator of one-carbon metabolism.

Structure (2015) 23:1375-81.

Aslan B et al.

The ZNF304-integrin axis protects against anoikis in cancer.

Nat Commun (2015) 6:7351.

Kwong RY et al.

Characterization of cardiac amyloidosis by atrial late gadolinium enhancement using contrast-enhanced cardiac Magnetic Resonance Imaging and correlation with left atrial conduit and contractile function.

Am J Cardiol (2015) 116:622-9.

Szabo L et al.

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.

Genome Biol (2015) 16:126.

Boettcher M & McManus MT.

Choosing the right tool for the job: RNAi, TALEN, or CRISPR.

Mol Cell (2015) 58:575-85.
Highly Cited (150+) 

Li X et al.

Lowering the quantification limit of the QubitTM RNA HS assay using RNA spike-in.

BMC Mol Biol (2015) 16:9.

Wong HK et al.

The Cancer Genome Atlas analysis predicts microRNA for targeting cancer growth and vascularization in glioblastoma.

Mol Ther (2015) 23:1234-47.
Related Pathway

Li K et al.

Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.

Circ Res (2015) 117:e1-e11.
Related Pathway

Miyake TM et al.

XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A.

Clin Cancer Res (2015) 21:3286-97.
Related Pathway

Liu X et al.

miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.

Cell Metab (2015) 21:584-95.
Related Pathway

Schwarzenbacher D et al.

Low spinophilin expression enhances aggressive biological behavior of breast cancer.

Oncotarget (2015) 6:11191-202.

Gilder AS et al.

Soluble Urokinase Receptor is released selectively by glioblastoma cells that express Epidermal Growth Factor Receptor variant III and promotes tumor cell migration and invasion.

J Biol Chem (2015) 290:14798-809.

Thanapprapa D Sr et al.

PTEN expression as a predictor of response to focal adhesion kinase inhibition in uterine cancer.

Mol Cancer Ther (2015) 14:1466-1475.

Ren A et al.

Structural basis for molecular discrimination by a 3′,3′-cGAMP sensing riboswitch.

Cell Rep (2015) 11:1-12.

Ling H et al.

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.

Gut (2016) 65:977-989.

Neilan TG et al.

Late gadolinium enhancement among survivors of sudden cardiac arrest.

JACC Cardiovasc Imaging (2015) 8:414-423.

Huan T et al.

Genome-wide identification of microRNA expression Quantitative Trait Loci.

Nat Commun (2015) 6:6601.

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