The Extracellular RNA Communication Consortium has published 800+ research articles since its inception in 2013. Articles in the category “exRNA and EV Biology” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Jeppesen DK et al.
Extracellular vesicles and nanoparticles: Emerging complexities.
Trends Cell Biol AOP 2023-02-01.
Gornalusse G et al.
Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen.
Mol Hum Reprod (2023) 29.
Costa B et al.
Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids.
Proc Natl Acad Sci U S A (2023) 120:e2216330120.
Driedonks T et al.
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina.
J Extracell Biol (2022) 1.
Huang Y et al.
Relationships of APOE genotypes with small RNA and protein cargo of brain tissue extracellular vesicles from patients with late-stage AD.
Neurol Genet (2022) 8:e200026.
Tosar JP, Cayota A & Witwer K.
Exomeres and supermeres: Monolithic or diverse?
J Extracell Biol (2022) 1.
Huang Y et al.
Brain tissue-derived extracellular vesicles in Alzheimer’s disease display altered key protein levels including cell type-specific markers.
J Alzheimers Dis (2022) 90:1057-1072.
Nguyen LTH et al.
An immunogold single extracellular vesicular RNA and protein ((Au) SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients.
J Extracell Vesicles (2022) 11:e12258.
Fordjour FK et al.
A shared, stochastic pathway mediates exosome protein budding along plasma and endosome membranes.
J Biol Chem (2022) 298:102394.
Lennon KM et al.
Cardiac troponin T in extracellular vesicles as a novel biomarker in human cardiovascular disease.
Clin Transl Med (2022) 12:e979.
Glass SE & Coffey RJ.
Recent advances in the study of extracellular vesicles in colorectal cancer.
Gastroenterology (2022) 163:1188-1197.
Davies MR et al.
Muscle-derived beige adipose precursors secrete promyogenic exosomes that treat rotator cuff muscle degeneration in mice and are identified in humans by single-cell RNA sequencing.
Am J Sports Med (2022) 50:2247-2257.
Gomes DE & Witwer KW.
L1CAM-associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization.
J Extracell Biol (2022) 1.
Zhu X et al.
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV.
Neurobiol Dis (2022) 169:105734.
Barman B et al.
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites.
Dev Cell (2022) 57:974-994.e8.
Li G et al.
Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs.
Adv Sci (2022) 9:e2200829.
Alsop E et al.
A novel tissue atlas and online tool for the interrogation of small RNA expression in human tissues and biofluids.
Front Cell Dev Biol (2022) 10:804164.
Phu TA et al.
IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity.
Mol Ther (2022) 30:2274-2297.
Abner JJ et al.
Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m(6)A consensus sequences.
Heliyon (2021) 7:e08519.
Couch Y et al.
A brief history of nearly EV-erything – The rise and rise of extracellular vesicles.
J Extracell Vesicles (2021) 10:e12144.
Zhang Q et al.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
Nat Cell Biol (2021) 23:1240-1254.
Hong BV et al.
Lipid-based nutrient supplementation increases High-Density Lipoprotein (HDL) cholesterol efflux capacity and is associated with changes in the HDL glycoproteome in children.
ACS Omega (2021) 6:32022-32031.
Bittel M et al.
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo.
J Extracell Vesicles (2021) 10:e12159.
Valkov N et al.
snRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life Sci Alliance (2021) 4.
Verweij FJ et al.
The power of imaging to understand extracellular vesicle biology in vivo.
Nat Methods (2021) 18:1013-1026.
Ma S et al.
CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance.
Cell Rep (2021) 36:109549.
Pusic KM, Kraig RP & Pusic AD.
IFNgamma-stimulated dendritic cell extracellular vesicles can be nasally administered to the brain and enter oligodendrocytes.
PLoS ONE (2021) 16:e0255778.
Bouchareychas L et al.
High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis.
iScience (2021) 24:102847.
Zheng JJ et al.
Isolation of HDL by sequential flotation ultracentrifugation followed by size exclusion chromatography reveals size-based enrichment of HDL-associated proteins.
Sci Rep (2021) 11:16086.
Pusic KM et al.
Environmental enrichment and its benefits for migraine: Dendritic cell extracellular vesicles as an effective mimetic.
J Cell Immunol (2021) 3:215-225.
Giraldez MD & Tewari M.
Phospho-RNAseq profiling of extracellular mRNAs and lncRNAs.
Methods Mol Biol (2021) 2348:257-271.
Kilinc S et al.
Oncogene-regulated release of extracellular vesicles.
Dev Cell (2021) 56:1989-2006.e6.
Guo C et al.
Choice of selectable marker affects recombinant protein expression in cells and exosomes.
J Biol Chem (2021) 297:100838.
Blanco-Dominguez R et al.
A novel circulating microRNA for the detection of acute myocarditis.
N Engl J Med (2021) 384:2014-2027.
Gimona M et al.
Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles.
Cytotherapy (2021) 23:373-380.
Witwer KW.
On your MARCKS, get set, deliver: Engineering extracellular vesicles.
Mol Ther (2021) 29:1664-1665.
Gruner HN & McManus MT.
Examining the evidence for extracellular RNA function in mammals.
Nat Rev Genet (2021) 22:448-458.
Tallon C et al.
Nipping disease in the bud: nSMase2 inhibitors as therapeutics in extracellular vesicle-mediated diseases.
Drug Discov Today (2021) 26:1656-1668.
Tosar JP et al.
RI-SEC-seq: Comprehensive profiling of nonvesicular extracellular RNAs with different stabilities.
Bio Protoc (2021) 11:e3918.
Martin-Jaular L et al.
Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection.
EMBO J (2021) 40:e105492.
Saheera S et al.
Extracellular vesicle interplay in cardiovascular pathophysiology.
Am J Physiol Heart Circ Physiol (2021) 320:H1749-H1761.
Ma S et al.
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype.
Cell Rep (2021) 34:108726.
Tosar JP, Witwer K & Cayota A.
Revisiting extracellular RNA release, processing, and function.
Trends Biochem Sci (2021) 46:438-445.
Tosar JP, Garcia-Silva MR & Cayota A.
Circulating SNORD57 rather than piR-54265 is a promising biomarker for colorectal cancer: Common pitfalls in the study of somatic piRNAs in cancer.
RNA (2021) 27:403-410.
Silverman DA et al.
Cancer-associated neurogenesis and nerve-cancer cross-talk.
Cancer Res (2021) 81:1431-1440.
Nieland L et al.
Extracellular vesicle-mediated bilateral communication between glioblastoma and astrocytes.
Trends Neurosci (2021) 44:215-226.
Li J et al.
miR-30d regulates cardiac remodeling by intracellular and paracrine signaling.
Circ Res (2020) 128:e1-e23.
Koyano K, Bahn JH & Xiao X.
Extracellular microRNA 3′ end modification across diverse body fluids.
Epigenetics (2021) 16:1000-1015.
Anfossi S & Calin GA.
Gut microbiota: a new player in regulating immune- and chemo-therapy efficacy.
Cancer Drug Resist (2020) 3:356-370.
Zhang Q et al.
Angiotensin-converting Enzyme 2-containing small extracellular vesicles and exomeres bind the Severe Acute Respiratory Syndrome Coronavirus 2 spike protein.
Gastroenterology (2021) 160:958-961.e3.
Zhao Z et al.
miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR-186-5p as a potential antiretroviral factor in macrophages.
FEBS Open Bio (2020) 10:2021-2039.
Xiao Y et al.
How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger.
J Extracell Vesicles (2020) 9:1793515.
Fazzalari A et al.
A translational model for venous thromboembolism: microRNA expression in hibernating black bears.
J Surg Res (2021) 257:203-212.
Zeng A et al.
Glioblastoma-derived extracellular vesicles facilitate transformation of astrocytes via reprogramming oncogenic metabolism.
iScience (2020) 23:101420.
Tosar JP et al.
Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome.
Nucleic Acids Res (2020) 48:12874-12888.
Drula R et al.
MicroRNAs from liquid biopsy derived extracellular vesicles: Recent advances in detection and characterization methods.
Cancers (Basel) (2020) 12:2009.
Bouchareychas L et al.
Macrophage exosomes resolve atherosclerosis by regulating hematopoiesis and inflammation via microRNA cargo.
Cell Rep (2020) 32:107881.
Koupenova M & Freedman JE.
Platelets and immunity: Going viral.
Arterioscler Thromb Vasc Biol (2020) 40:1605-1607.
Abels ER et al.
GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma.
Sci Rep (2020) 10:9898.
O’Brien K et al.
RNA delivery by extracellular vesicles in mammalian cells and its applications.
Nat Rev Mol Cell Biol (2020) 21:585-606.
Sung BH et al.
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells.
Nat Commun (2020) 11:2092.
Maas SLN et al.
Glioblastoma hijacks microglial gene expression to support tumor growth.
J Neuroinflammation (2020) 17:120.
Ahn JY et al.
Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria.
Biochim Biophys Acta Gen Subj (2021) 1865:129598.
Lucero R et al.
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells.
Cell Rep (2020) 30:2065-2074.e4.
Yekula A et al.
Extracellular vesicles in glioblastoma tumor microenvironment.
Front Immunol (2019) 10:3137.
Ghai V et al.
Alterations in plasma microRNA and protein levels in war veterans with chronic mild traumatic brain injury.
J Neurotrauma (2020) 37:1418-1430.
Perez PS et al.
Extracellular vesicles and chronic inflammation during HIV infection.
J Extracell Vesicles (2019) 8:1687275.
Meyer C et al.
The G3BP1-Family-USP10 deubiquitinase complex rescues ubiquitinated 40S subunits of ribosomes stalled in translation from lysosomal degradation.
Mol Cell (2020) 77:1193-1205.e5.
Gambaro F et al.
Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner.
RNA Biol (2019) 17:1168-1182.
De Los Santos MC, Dragomir MP & Calin GA.
The role of exosomal long non-coding RNAs in cancer drug resistance.
Cancer Drug Resist (2019) 2:1178-1192.
Kalra H et al.
Extracellular vesicles containing oncogenic mutant beta-catenin activate Wnt signalling pathway in the recipient cells.
J Extracell Vesicles (2019) 8:1690217.
Weaver AM & Patton JG.
Argonautes in extracellular vesicles: Artifact or selected cargo?
Cancer Res (2020) 80:379-381.
Russell AE et al.
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop.
J Extracell Vesicles (2019) 8:1684862.
Zaborowski MP et al.
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.
Sci Rep (2019) 9:17387.
Sun L et al.
miR-302a inhibits metastasis and cetuximab resistance in colorectal cancer by targeting NFIB and CD44.
Theranostics (2019) 9:8409-8425.
Gupta MP et al.
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.
Nat Methods (2019) 16:1269-1273.
Sundaram K et al.
Plant-derived exosomal nanoparticles inhibit pathogenicity of Porphyromonas gingivalis.
iScience (2019) 21:308-327.
Lee MJ et al.
The impact of Moyamoya disease and RNF213 mutations on the spectrum of plasma protein and microRNA.
J Clin Med (2019) 8:1648.
Jones PS et al.
Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma.
EBioMedicine (2019) 48:23-35.
Bei Y et al.
Correction to: Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury.
Basic Res Cardiol (2019) 114:44.
Pusic KM et al.
IFNgamma-stimulated dendritic cell exosomes for treatment of migraine modeled using spreading depression.
Front Neurosci (2019) 13:942.
Abels ER et al.
Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21.
Cell Rep (2019) 28:3105-3119.e7.
Kanada M et al.
Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy.
Mol Cancer Ther (2019) 18:2331-2342.
Fabbri M et al.
Decrypting noncoding RNA interactions, structures, and functional networks.
Genome Res (2019) 29:1377-1388.
Lee MY et al.
Distinct profiles of cell-free microRNAs in plasma of veterans with Post-Traumatic Stress Disorder.
J Clin Med (2019) 8:963.
Gyuris A et al.
Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity.
Cell Rep (2019) 27:3972-3987.e6.
Haraszti RA et al.
Serum deprivation of Mesenchymal Stem Cells improves exosome activity and alters lipid and protein composition.
iScience (2019) 16:230-241.
Tapparo M et al.
Renal regenerative potential of extracellular vesicles derived from miRNA-engineered Mesenchymal Stromal Cells.
Int J Mol Sci (2019) 20:2381.
Bruno S et al.
Role of extracellular vesicles in stem cell biology.
Am J Physiol Cell Physiol (2019) 317:C303-C313.
Wei Z et al.
Co-cultures of glioma stem cells and primary neurons, astrocytes, microglia, and endothelial cells for investigation of intercellular communication in the brain.
Front Neurosci (2019) 13:361.
Poggio M et al.
Suppression of exosomal PD-L1 induces systemic anti-tumor immunity and memory.
Cell (2019) 177:414-427.e13.
Das S et al.
The Extracellular RNA Communication Consortium: Establishing foundational knowledge and technologies for extracellular RNA research.
Cell (2019) 177:231-242.
Murillo OD et al.
exRNA Atlas analysis reveals distinct extracellular RNA Cargo types and their carriers present across human biofluids.
Cell (2019) 177:463-477.e15.
Roy S et al.
Navigating the landscape of tumor extracellular vesicle heterogeneity.
Int J Mol Sci (2019) 20:6.
Pua HH et al.
Increased hematopoietic extracellular RNAs and vesicles in the lung during allergic airway responses.
Cell Rep (2019) 26:933-944.e4.
Jimenez L et al.
Quantitative proteomic analysis of small and large extracellular vesicles (EVs) reveals enrichment of adhesion proteins in small EVs.
J Proteome Res (2019) 18:947-959.
Chiou NT, Kageyama R & Ansel KM.
Selective export into extracellular vesicles and function of tRNa fragments during T cell activation.
Cell Rep (2018) 25:3356-3370.e4.
Kanlikilicer P et al.
Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer.
EBioMedicine (2018) 38:100-112.
Teng Y et al.
Plant-derived exosomal microRNAs shape the gut microbiota.
Cell Host Microbe (2018) 24:637-652.e8.
Wang QL et al.
Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways.
Theranostics (2018) 8:4912-4924.
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Hinger SA et al.
Diverse long RNAs are differentially sorted into extracellular vesicles secreted by colorectal cancer cells.
Cell Rep (2018) 25:715-725.e4.
Gustafsson G et al.
Secretion and uptake of alpha-synuclein via extracellular vesicles in cultured cells.
Cell Mol Neurobiol (2018) 38:1539-1550.
Malabirade A et al.
The RNA complement of Outer Membrane Vesicles from Salmonella enterica Serovar Typhimurium under distinct culture conditions.
Front Microbiol (2018) 9:2015.
Moirangthem A & Patel T.
Mesenchymal stem cell derived extracellular vesicles: a promising new therapeutic approach for hepatic injury.
Biotarget (2017) 1:12.
Regev K et al.
Identification of MS-specific serum miRNAs in an international multicenter study.
Neurol Neuroimmunol Neuroinflamm (2018) 5:e491.
Dragomir M, Chen B & Calin GA.
Exosomal lncRNAs as new players in cell-to-cell communication.
Transl Cancer Res (2018) 7:S243-S252.
Raffai RL.
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis.
Noncoding RNA Investig (2018) 2:43.
Broekman ML et al.
Multidimensional communication in the microenvirons of glioblastoma.
Nat Rev Neurol (2018) 14:482-495.
Sung BH & Weaver AM.
Directed migration: Cells navigate by extracellular vesicles.
J Cell Biol (2018) 217:2613-2614.
Zhang Q et al.
Mutant KRAS exosomes alter the metabolic state of recipient colonic epithelial cells.
Cell Mol Gastroenterol Hepatol (2018) 5:627-629.e6.
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs.
Front Oncol (2018) 8:179.
Danielson KM et al.
Plasma circulating extracellular RNAs in Left Ventricular Remodeling post-Myocardial Infarction.
EBioMedicine (2018) 32:172-181.
He X et al.
Human tRNA-derived small RNAs modulate host-oral microbial interactions.
J Dent Res (2018) 97:1236-1243.
Vujic A et al.
Exercise induces new cardiomyocyte generation in the adult mammalian heart.
Nat Commun (2018) 9:1659.
Koupenova M et al.
Micro RNAs from DNA viruses are found widely in plasma in a large observational human population.
Sci Rep (2018) 8:6397.
Haemmerle M et al.
The platelet lifeline to cancer: Challenges and opportunities.
Cancer Cell (2018) 33:965-983.
Ricklefs FL et al.
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.
Sci Adv (2018) 4:eaar2766.
Roy S, Hochberg FH & Jones PS.
Extracellular vesicles: the growth as diagnostics and therapeutics; a survey.
J Extracell Vesicles (2018) 7:1438720.
Lankford KL et al.
Intravenously delivered mesenchymal stem cell-derived exosomes target M2-type macrophages in the injured spinal cord.
PLoS ONE (2018) 13:e0190358.
Nonaka T & Wong DTW.
Saliva exosomics in cancer: Molecular characterization of cancer-derived exosomes in saliva.
Enzymes (2017) 42:125-151.
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones.
Mol Oncol (2017) 11:1673-1686.
Nguyen TA et al.
SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition.
Immunity (2017) 47:498-509.e6.
Figueroa J et al.
Exosomes from glioma-associated mesenchymal stem cells increase the tumorigenicity of glioma stem-like cells via transfer of miR-1587.
Cancer Res (2017) 77:5808-5819.
Datta A et al.
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
Cancer Lett (2017) 408:73-81.
Bei Y et al.
Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury.
Basic Res Cardiol (2017) 112:38.
Silva AM et al.
Dendritic cell-derived extracellular vesicles mediate mesenchymal stem/stromal cell recruitment.
Sci Rep (2017) 7:1667.
Bruno S et al.
Renal regenerative potential of different extracellular vesicle populations derived from bone marrow mesenchymal stromal cells.
Tissue Eng Part A (2017) 23:1262-1273.
Rashed MH et al.
Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget (2017) 8:20145-20164.
Haga H et al.
Extracellular vesicles from bone marrow-derived mesenchymal stem cells protect against murine hepatic ischemia/reperfusion injury.
Liver Transpl (2017) 23:791-803.
Yeri A et al.
Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects.
Sci Rep (2017) 7:44061.
Clancy L et al.
The role of RNA uptake in platelet heterogeneity.
Thromb Haemost (2017) 117:948-961.
Deng Z et al.
Broccoli-derived nanoparticle inhibits mouse colitis by activating dendritic cell AMP-activated protein kinase.
Mol Ther (2017) 25:1641-1654.
Teng Y et al.
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression.
Nat Commun (2017) 8:14448.
Collino F et al.
Exosome and microvesicle-enriched fractions isolated from mesenchymal stem cells by gradient separation showed different molecular signatures and functions on renal tubular epithelial cells.
Stem Cell Rev (2017) 13:226-243.
Maji S et al.
Extracellular vesicles in liver diseases.
Am J Physiol Gastrointest Liver Physiol (2017) 312:G194-G200.
Maas SL, Breakefield XO & Weaver AM.
Extracellular vesicles: Unique intercellular delivery vehicles.
Trends Cell Biol (2017) 27:172-188.
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases.
Best Pract Res Clin Endocrinol Metab (2016) 30:577-590.
Katsiougiannis S et al.
Saliva exosomes from pancreatic tumor-bearing mice modulate NK cell phenotype and antitumor cytotoxicity.
FASEB J (2017) 31:998-1010.
Nazimek K, Bryniarski K & Askenase PW.
Functions of exosomes and microbial extracellular vesicles in allergy and contact and delayed-type hypersensitivity.
Int Arch Allergy Immunol (2016) 171:1-26.
Kanlikilicer P et al.
Ubiquitous release of exosomal tumor suppressor miR-6126 from ovarian cancer cells.
Cancer Res (2016) 76:7194-7207.
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Deng Z et al.
Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis.
Oncogene (2017) 36:639-651.
Wang JQ et al.
Extracellular vesicle-mediated reversal of paclitaxel resistance in prostate cancer.
Crit Rev Oncog (2015) 20:407-17.
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation.
Annu Rev Nutr (2016) 36:301-36.
Soares VY et al.
Extracellular vesicles derived from human vestibular schwannomas associated with poor hearing damage cochlear cells.
Neuro Oncol (2016) 18:1498-1507.
Zhang HG et al.
Isolation, identification, and characterization of novel nanovesicles.
Oncotarget (2016) 7:41346-41362.
McKenzie AJ et al.
KRAS-MEK signaling controls Ago2 sorting into exosomes.
Cell Rep (2016) 15:978-87.
Abels ER & Breakefield XO.
Introduction to extracellular vesicles: Biogenesis, RNA cargo selection, content, release, and uptake.
Cell Mol Neurobiol (2016) 36:301-12.
Wu SY et al.
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Nat Commun (2016) 7:11169.
Zappulli V et al.
Extracellular vesicles and intercellular communication within the nervous system.
J Clin Invest (2016) 126:1198-207.
Teng Y et al.
Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages.
Oncotarget (2016) 7:25683-97.
Pusic KM, Pusic AD & Kraig RP.
Environmental enrichment stimulates immune cell secretion of exosomes that promote CNS myelination and may regulate inflammation.
Cell Mol Neurobiol (2016) 36:313-325.
Pucci F et al.
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.
Science (2016) 352:242-6.
Almeida MI & Calin GA.
The miR-143/miR-145 cluster and the tumor microenvironment: Unexpected roles.
Genome Med (2016) 8:29.
Zaborowski MP et al.
Extracellular vesicles: Composition, biological relevance, and methods of study.
Bioscience (2015) 65:783-797.
Zhang X et al.
Potential transfer of polyglutamine and CAG-repeat RNA in extracellular vesicles in Huntington’s disease: Background and evaluation in cell culture.
Cell Mol Neurobiol (2016) 36:459-70.
Iavello A et al.
Role of Alix in miRNA packaging during extracellular vesicle biogenesis.
Int J Mol Med (2016) 37:958-66.
Rupaimoole R et al.
miRNA deregulation in cancer cells and the tumor microenvironment.
Cancer Discov (2016) 6:235-46.
Clancy L & Freedman JE.
Blood-derived extracellular RNA and platelet pathobiology: Adding pieces to a complex circulating puzzle.
Circ Res (2016) 118:374-6.
Rupaimoole R et al.
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Oncogene (2016) 35:4312-20. Related blog post
Rupaimoole R et al.
Long noncoding RNA ceruloplasmin promotes cancer growth by altering glycolysis.
Cell Rep (2015) 13:2395-402.
Machtinger R, Laurent LC & Baccarelli AA.
Extracellular vesicles: Roles in gamete maturation, fertilization and embryo implantation.
Hum Reprod Update (2016) 22:182-93.
Zhuang X et al.
Ginger-derived nanoparticles protect against alcohol-induced liver damage.
J Extracell Vesicles (2015) 4:28713.
Silva A, Bullock M & Calin G.
The clinical relevance of long non-coding RNAs in cancer.
Cancers (2015) 7:2169-82.
van der Vos KE et al.
Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain.
Neuro Oncol (2016) 18:58-69.
Quesenberry PJ et al.
Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming.
Stem Cell Res Ther (2015) 6:153.
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma.
Curr Opin Immunol (2015) 36:101-8.
Pichler M & Calin GA.
MicroRNAs in cancer: From developmental genes in worms to their clinical application in patients.
Br J Cancer (2015) 113:569-73.
Pusic AD & Kraig RP.
Phasic treatment with Interferon gamma stimulates release of exosomes that protect against spreading depression.
J Interferon Cytokine Res (2015) 35:795-807.
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity.
J Clin Invest (2015) 125:2242-9.
Sung BH et al.
Directional cell movement through tissues is controlled by exosome secretion.
Nat Commun (2015) 6:7164.
Bryniarski K et al.
Free extracellular miRNA functionally targets cells by transfecting exosomes from their companion cells.
PLoS ONE (2015) 10:e0122991.
Agarwal K et al.
Analysis of exosome release as a cellular response to MAPK pathway inhibition.
Langmuir (2015) 31:5440-8.
Deng Z et al.
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Nat Commun (2015) 6:6956.
Collino F et al.
AKI recovery induced by mesenchymal stromal cell-derived extracellular vesicles carrying microRNAs.
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