The Extracellular RNA Communication Consortium has published 700+ research articles since its inception in 2013. Articles in the category “exRNA Biology” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Johansson K, Woodruff PG & Ansel KM.
Regulation of airway immunity by epithelial miRNAs.
Giraldez MD & Tewari M.
Phospho-RNAseq profiling of extracellular mRNAs and lncRNAs.
Methods Mol Biol (2021) 2348:257-271.
Blanco-Dominguez R et al.
A novel circulating microRNA for the detection of acute myocarditis.
N Engl J Med (2021) 384:2014-2027.
Gruner HN & McManus MT.
Examining the evidence for extracellular RNA function in mammals.
Nat Rev Genet (2021) 22:448-458.
Tosar JP et al.
RI-SEC-seq: Comprehensive profiling of nonvesicular extracellular RNAs with different stabilities.
Tosar JP, Witwer K & Cayota A.
Revisiting extracellular RNA release, processing, and function.
Trends Biochem Sci (2021) 46:438-445.
Tosar JP, Garcia-Silva MR & Cayota A.
Koyano K, Bahn JH & Xiao X.
Extracellular microRNA 3′ end modification across diverse body fluids.
Epigenetics (2021) 16:1000-1015.
Li J et al.
miR-30d regulates cardiac remodeling by intracellular and paracrine signaling.
Zhao Z et al.
FEBS Open Bio (2020) 10:2021-2039.
Xiao Y et al.
How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger.
J Extracell Vesicles (2020) 9:1793515.
Fazzalari A et al.
A translational model for venous thromboembolism: microRNA expression in hibernating black bears.
J Surg Res (2021) 257:203-212.
Zeng A et al.
Tosar JP et al.
Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome.
Nucleic Acids Res (2020) 48:12874-12888.
Drula R et al.
Cancers (Basel) (2020) 12:2009.
Bouchareychas L et al.
Abels ER et al.
Ahn JY et al.
Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria.
Biochim Biophys Acta Gen Subj (2021) 1865:129598.
Tosar JP & Cayota A.
Extracellular tRNAs and tRNA-derived fragments.
Ghai V et al.
J Neurotrauma (2020) 37:1418-1430.
Meyer C et al.
Mol Cell (2020) 77:1193-1205.e5.
Gambaro F et al.
De Los Santos MC, Dragomir MP & Calin GA.
The role of exosomal long non-coding RNAs in cancer drug resistance.
Cancer Drug Resist (2019) 2:1178-1192.
Sun L et al.
Theranostics (2019) 9:8409-8425.
Lee MJ et al.
The impact of Moyamoya disease and RNF213 mutations on the spectrum of plasma protein and microRNA.
Fabbri M et al.
Decrypting noncoding RNA interactions, structures, and functional networks.
Genome Res (2019) 29:1377-1388.
Gyuris A et al.
Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity.
Cell Rep (2019) 27:3972-3987.e6.
Murillo OD et al.
Das S et al.
Bach DH, Lee SK & Sood AK.
Mol Ther Nucleic Acids (2019) 16:118-129.
Godoy PM et al.
Large differences in small RNA composition between human biofluids.
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Regev K et al.
Identification of MS-specific serum miRNAs in an international multicenter study.
Neurol Neuroimmunol Neuroinflamm (2018) 5:e491.
Raffai RL.
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis.
Noncoding RNA Investig (2018) 2:43.
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs.
Dluzen DF et al.
Extracellular RNA profiles with human age.
Danielson KM et al.
Plasma circulating extracellular RNAs in Left Ventricular Remodeling post-Myocardial Infarction.
EBioMedicine (2018) 32:172-181.
He X et al.
Human tRNA-derived small RNAs modulate host-oral microbial interactions.
J Dent Res (2018) 97:1236-1243.
Vujic A et al.
Exercise induces new cardiomyocyte generation in the adult mammalian heart.
Koupenova M et al.
Micro RNAs from DNA viruses are found widely in plasma in a large observational human population.
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones.
Mol Oncol (2017) 11:1673-1686.
Nguyen TA et al.
SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition.
Immunity (2017) 47:498-509.e6.
Shah R et al.
Am J Physiol Heart Circ Physiol (2017) 313:H1162-H1167.
Yeri A et al.
Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects.
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases.
Best Pract Res Clin Endocrinol Metab (2016) 30:577-590.
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation.
Annu Rev Nutr (2016) 36:301-36.
Wu SY et al.
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Rupaimoole R et al.
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Oncogene (2016) 35:4312-20. Related blog post
Rupaimoole R et al.
Long noncoding RNA ceruloplasmin promotes cancer growth by altering glycolysis.
Giza DE & Calin GA
microRNA and Chronic Lymphocytic Leukemia.
Adv Exp Med Biol (2015) 889:23-40.
Shields BB et al.
A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.
Mol Syst Biol (2015) 11:842.
Related Pathways: 1, 2
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma.
Curr Opin Immunol (2015) 36:101-8.
Pichler M & Calin GA.
MicroRNAs in cancer: From developmental genes in worms to their clinical application in patients.
Br J Cancer (2015) 113:569-73.
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity.
J Clin Invest (2015) 125:2242-9.
Berindan-Neagoe I & Calin GA.
Molecular pathways: microRNAs, cancer cells, and microenvironment.
Clin Cancer Res (2014) 20:6247-53.
Rupaimoole R et al.
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Krzeszinski JY et al.
MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.
Nature (2014) 512:431-5.
Related Pathway
Takahashi K et al.
Long noncoding RNA in liver diseases.
Hepatology (2014) 60:744-53.
Related Pathway
Takahashi K et al.
Modulation of hypoxia-signaling pathways by extracellular linc-RoR.
J Cell Sci (2014) 127:1585-94.
Clancy L & Freedman JE.
New paradigms in thrombosis: Novel mediators and biomarkers platelet RNA transfer.