The Extracellular RNA Communication Consortium has published 800+ research articles since its inception in 2013. Articles in the category “exRNA Biology” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Dragomir MP et al.
Anti-miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response.
J Clin Invest (2023) 133.
LaPlante EL et al.
exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers.
Cell Genom (2023) 3:100303.
Barman B, Dawson TR & Weaver AM.
ER membrane contact sites: Key platforms for biogenesis of RNA-containing extracellular vesicles.
Contact (2022) 5.
Jeppesen DK et al.
Extracellular vesicles and nanoparticles: Emerging complexities.
Trends Cell Biol AOP 2023-02-01.
Gornalusse G et al.
Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen.
Mol Hum Reprod (2023) 29.
Costa B et al.
Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids.
Proc Natl Acad Sci U S A (2023) 120:e2216330120.
Castleberry M et al.
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages.
J Lipid Res (2023) 64:100328.
Tosar JP, Cayota A & Witwer K.
Exomeres and supermeres: Monolithic or diverse?
J Extracell Biol (2022) 1.
Michell DL et al.
Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions.
J Biol Chem (2022) 298:101952.
Barman B et al.
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites.
Dev Cell (2022) 57:974-994.e8.
Chen B et al.
Targeting non-coding RNAs to overcome cancer therapy resistance.
Signal Transduct Target Ther (2022) 7:121.
Li G et al.
Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs.
Adv Sci (2022) 9:e2200829.
Alsop E et al.
A novel tissue atlas and online tool for the interrogation of small RNA expression in human tissues and biofluids.
Front Cell Dev Biol (2022) 10:804164.
Abner JJ et al.
Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m(6)A consensus sequences.
Heliyon (2021) 7:e08519.
Dragomir MP, Knutsen E & Calin GA.
Classical and noncanonical functions of miRNAs in cancers.
Trends Genet (2022) 38:379-394.
Giraldez MD & Tewari M.
Phospho-RNAseq profiling of extracellular mRNAs and lncRNAs.
Methods Mol Biol (2021) 2348:257-271.
Blanco-Dominguez R et al.
A novel circulating microRNA for the detection of acute myocarditis.
N Engl J Med (2021) 384:2014-2027.
Gruner HN & McManus MT.
Examining the evidence for extracellular RNA function in mammals.
Nat Rev Genet (2021) 22:448-458.
Tosar JP et al.
RI-SEC-seq: Comprehensive profiling of nonvesicular extracellular RNAs with different stabilities.
Bio Protoc (2021) 11:e3918.
Tosar JP, Witwer K & Cayota A.
Revisiting extracellular RNA release, processing, and function.
Trends Biochem Sci (2021) 46:438-445.
Tosar JP, Garcia-Silva MR & Cayota A.
Circulating SNORD57 rather than piR-54265 is a promising biomarker for colorectal cancer: Common pitfalls in the study of somatic piRNAs in cancer.
RNA (2021) 27:403-410.
Li J et al.
miR-30d regulates cardiac remodeling by intracellular and paracrine signaling.
Circ Res (2020) 128:e1-e23.
Koyano K, Bahn JH & Xiao X.
Extracellular microRNA 3′ end modification across diverse body fluids.
Epigenetics (2021) 16:1000-1015.
Zhao Z et al.
miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR-186-5p as a potential antiretroviral factor in macrophages.
FEBS Open Bio (2020) 10:2021-2039.
Xiao Y et al.
How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger.
J Extracell Vesicles (2020) 9:1793515.
Fazzalari A et al.
A translational model for venous thromboembolism: microRNA expression in hibernating black bears.
J Surg Res (2021) 257:203-212.
Zeng A et al.
Glioblastoma-derived extracellular vesicles facilitate transformation of astrocytes via reprogramming oncogenic metabolism.
iScience (2020) 23:101420.
Tosar JP et al.
Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome.
Nucleic Acids Res (2020) 48:12874-12888.
Drula R et al.
MicroRNAs from liquid biopsy derived extracellular vesicles: Recent advances in detection and characterization methods.
Cancers (Basel) (2020) 12:2009.
Bouchareychas L et al.
Macrophage exosomes resolve atherosclerosis by regulating hematopoiesis and inflammation via microRNA cargo.
Cell Rep (2020) 32:107881.
Abels ER et al.
GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma.
Sci Rep (2020) 10:9898.
Ahn JY et al.
Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria.
Biochim Biophys Acta Gen Subj (2021) 1865:129598.
Ghai V et al.
Alterations in plasma microRNA and protein levels in war veterans with chronic mild traumatic brain injury.
J Neurotrauma (2020) 37:1418-1430.
Meyer C et al.
The G3BP1-Family-USP10 deubiquitinase complex rescues ubiquitinated 40S subunits of ribosomes stalled in translation from lysosomal degradation.
Mol Cell (2020) 77:1193-1205.e5.
Gambaro F et al.
Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner.
RNA Biol (2019) 17:1168-1182.
De Los Santos MC, Dragomir MP & Calin GA.
The role of exosomal long non-coding RNAs in cancer drug resistance.
Cancer Drug Resist (2019) 2:1178-1192.
Sun L et al.
miR-302a inhibits metastasis and cetuximab resistance in colorectal cancer by targeting NFIB and CD44.
Theranostics (2019) 9:8409-8425.
Lee MJ et al.
The impact of Moyamoya disease and RNF213 mutations on the spectrum of plasma protein and microRNA.
J Clin Med (2019) 8:1648.
Fabbri M et al.
Decrypting noncoding RNA interactions, structures, and functional networks.
Genome Res (2019) 29:1377-1388.
Gyuris A et al.
Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity.
Cell Rep (2019) 27:3972-3987.e6.
Das S et al.
The Extracellular RNA Communication Consortium: Establishing foundational knowledge and technologies for extracellular RNA research.
Cell (2019) 177:231-242.
Murillo OD et al.
exRNA Atlas analysis reveals distinct extracellular RNA Cargo types and their carriers present across human biofluids.
Cell (2019) 177:463-477.e15.
Godoy PM et al.
Large differences in small RNA composition between human biofluids.
Cell Rep (2018) 25:1346-1358.
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Regev K et al.
Identification of MS-specific serum miRNAs in an international multicenter study.
Neurol Neuroimmunol Neuroinflamm (2018) 5:e491.
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis.
Noncoding RNA Investig (2018) 2:43.
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs.
Front Oncol (2018) 8:179.
Danielson KM et al.
Plasma circulating extracellular RNAs in Left Ventricular Remodeling post-Myocardial Infarction.
EBioMedicine (2018) 32:172-181.
He X et al.
Human tRNA-derived small RNAs modulate host-oral microbial interactions.
J Dent Res (2018) 97:1236-1243.
Vujic A et al.
Exercise induces new cardiomyocyte generation in the adult mammalian heart.
Nat Commun (2018) 9:1659.
Koupenova M et al.
Micro RNAs from DNA viruses are found widely in plasma in a large observational human population.
Sci Rep (2018) 8:6397.
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones.
Mol Oncol (2017) 11:1673-1686.
Nguyen TA et al.
SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition.
Immunity (2017) 47:498-509.e6.
Shah R et al.
Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: Brief report.
Am J Physiol Heart Circ Physiol (2017) 313:H1162-H1167.
Yeri A et al.
Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects.
Sci Rep (2017) 7:44061.
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases.
Best Pract Res Clin Endocrinol Metab (2016) 30:577-590.
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation.
Annu Rev Nutr (2016) 36:301-36.
Wu SY et al.
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Nat Commun (2016) 7:11169.
Rupaimoole R et al.
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Oncogene (2016) 35:4312-20. Related blog post
Rupaimoole R et al.
Long noncoding RNA ceruloplasmin promotes cancer growth by altering glycolysis.
Cell Rep (2015) 13:2395-402.
Shields BB et al.
A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.
Mol Syst Biol (2015) 11:842.
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma.
Curr Opin Immunol (2015) 36:101-8.
Pichler M & Calin GA.
MicroRNAs in cancer: From developmental genes in worms to their clinical application in patients.
Br J Cancer (2015) 113:569-73.
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity.
J Clin Invest (2015) 125:2242-9.
Berindan-Neagoe I & Calin GA.
Molecular pathways: microRNAs, cancer cells, and microenvironment.
Clin Cancer Res (2014) 20:6247-53.
Rupaimoole R et al.
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Nat Commun (2014) 5:5202.
Krzeszinski JY et al.
MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.
Nature (2014) 512:431-5.
Takahashi K et al.
Long noncoding RNA in liver diseases.
Hepatology (2014) 60:744-53.
Takahashi K et al.
Modulation of hypoxia-signaling pathways by extracellular linc-RoR.
J Cell Sci (2014) 127:1585-94.