The top 20 most highly cited articles from the Extracellular RNA Communication Consortium are listed here. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles. Clicking on the “Highly Cited” tag for an article links to its entry at Google Scholar.

Highly Cited

Melo SA et al.

Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.

Cancer Cell (2014) 26:707-21.

Sercombe L et al.

Advances and challenges of liposome assisted drug delivery.

Front Pharmacol (2015) 6:286.

Akers JC et al.

Biogenesis of extracellular vesicles (EV): Exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies.

J Neurooncol (2013) 113:1-11.

Keerthikumar S et al.

ExoCarta: A web-based compendium of exosomal cargo.

J Mol Biol (2016) 428:688-692.

Bahn JH et al.

The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva.

Clin Chem (2015) 61:221-30.

Berindan-Neagoe I et al.

MicroRNAome genome: a treasure for cancer diagnosis and therapy.

CA Cancer J Clin (2014) 64:311-36.

Lai CP et al.

Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter.

ACS Nano (2014) 8:483-94.

Byron SA et al.

Translating RNA sequencing into clinical diagnostics: Opportunities and challenges.

Nat Rev Genet (2016) 17:257-71. Related blog post

Krzeszinski JY et al.

MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.

Nature (2014) 512:431-5.
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Pecot CV et al.

Tumour angiogenesis regulation by the miR-200 family.

Nat Commun (2013) 4:2427.

Boettcher M & McManus MT.

Choosing the right tool for the job: RNAi, TALEN, or CRISPR.

Mol Cell (2015) 58:575-85.

Gyorgy B et al.

Therapeutic applications of extracellular vesicles: Clinical promise and open questions.

Annu Rev Pharmacol Toxicol (2015) 55:439-64.

Vader P, Breakefield XO & Wood MJ.

Extracellular vesicles: Emerging targets for cancer therapy.

Trends Mol Med (2014) 20:385-393.

Sung BH et al.

Directional cell movement through tissues is controlled by exosome secretion.

Nat Commun (2015) 6:7164.

Ozpolat B, Sood AK & Lopez-Berestein G.

Liposomal siRNA nanocarriers for cancer therapy.

Adv Drug Deliv Rev (2014) 66:110-6.
Related Pathway


Kanada M et al.

Differential fates of biomolecules delivered to target cells via extracellular vesicles.

Proc Natl Acad Sci U S A (2015) 112:E1433-42.

Chen WW et al.

BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles.

Mol Ther Nucleic Acids (2013) 2:e109.

Wu SY et al.

RNAi therapies: Drugging the undruggable.

Sci Transl Med (2014) 6:240ps7.

Lai CP & Breakefield XO.

Role of exosomes/microvesicles in the nervous system and use in emerging therapies.

Front Physiol (2012) 3:228.

Lau C et al.

Role of pancreatic cancer-derived exosomes in salivary biomarker development.

J Biol Chem (2013) 288:26888-97.