The ERCC webinar series provides researchers studying extracellular RNA and extracellular vesicles the opportunity to present their latest work to a diverse audience. Webinars occur on the first Thursday of each month (except August) at 10 am Pacific / 12 noon Central / 1 pm Eastern time. Exceptions to the regular schedule will be announced here ahead of time.
No ERCC webinar has yet been scheduled for October. In November, Michael Segel from the Zhang lab at MIT will speak. He is the first author of an exciting new paper in Science characterizing the PEG10 protein, of retroviral origin, which transports its own mRNA between cells. The team is working to engineer PEG10 into a vector for RNA therapy.
Segel M et al. Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Science (2021) 373: 882–889
https://pubmed.ncbi.nlm.nih.gov/34413232/
You can find previous webinar videos on the ERCC Youtube channel. All webinars, including those where video was not recorded or has not yet been released, are listed below.
DIE HARD: non-vesicular exRNA metabolism |
| Juan Pablo Tosar, University of the Republic of Uruguay & Pasteur Institute of Montevideo |
| Consortium member |
| September 2nd, 2021 |
Tackling challenges of extracellular vesicle-based therapeutic development |
| Steven M. Jay, University of Maryland College Park |
| Guest speaker |
| July 1st, 2021 |
Nanomaterials and RNA engineering for mRNA therapeutics, genome editing, and cell therapy |
| Yizhou Dong, The Ohio State University |
| Guest speaker |
| June 3rd, 2021 |
The Human Biofluid RNA Atlas |
| Pieter Mestdagh, University of Ghent and Cancer Research Institute Ghent (CRIG) |
| Guest speaker |
| April 1st, 2021 |
Can we use a crowdsourcing challenge to benchmark exRNA transcriptomics analyses? |
| Gustavo Stolovitzky, Chair, IBM Exploratory Life Sciences Program |
| Guest speaker |
| February 4th, 2021 |
Cell entry and molecular target of placental small EVs |
| Yingshi Ouyang, Magee‐Womens Research Institute, University of Pittsburgh School of Medicine |
| Guest speaker |
| December 3rd, 2020 |
| Video not available. |
Arthropod Exosomes: one target at multiple crossroads of vector-borne diseases |
| Hameeda Sultana, Center for Molecular Medicine, Old Dominion University |
| Guest speaker |
| November 5th, 2020 |
| Video not available. |
Extracellular vesicles and RNAs from virally infected cells |
| Fatah Kashanchi, George Mason University |
| Guest speaker |
| September 3rd, 2020 |
| Video available after manuscript publication. |
Nanoplasmonic sensing technologies for EV analysis |
| Hyungsoon Im, Center for Systems Biology, Mass General & Harvard Med |
| Guest speaker |
| July 9th, 2020 |
| Video not available. |
Problems Inside and Out: Viral-Like Impacts of Glioma Extracellular Vesicles on Normal Brain Cells |
| Michael Graner, Department of Neurosurgery, U Colorado Anschutz Medical Campus |
| Guest speaker |
| June 4th, 2020 |
Presymptomatic increase of an extracellular RNA in blood plasma associates with the development of Alzheimer’s disease |
| Sheng Zhong, UC San Diego Department of Bioengineering |
| Guest speaker |
| May 7th, 2020 |
Mechanisms of extracellular vesicle formation |
| Veronika Kralj-Iglic, Laboratory of Clinical Biophysics, University of Ljubljana |
| Guest speaker |
| March 5th, 2020 |
| Video not yet available. |
Engineered exosomes for neuronal delivery |
| Anastasia Khvorova, RNA Therapeutics Institute, U Mass Med |
| Consortium member |
| February 6th, 2020 |
Extracellular vesicles for cancer diagnosis and therapeutics |
| Siyang Zheng, Carnegie Mellon |
| Guest Speaker |
| 5 December 2019 |
Isolation, tissue-specific RNA markers, and early cancer detection studies in circulating extracellular vesicles from prostate and liver cancer patients |
| Gustavo A. Stolovitzky, IBM T.J. Watson Research Center |
| Guest Speaker |
| 7 November 2019 |
exRNA Atlas and deconvolution tools at the transition from ERCC1 to ERCC2 |
| Emily LaPlante, Baylor College of Medicine, ERCC DMRR |
| Consortium Member |
| 5 September 2019 |
| A related paper was published in the collection of ERCC1 papers at Cell Press. |
| Video not available. |
Transfer of Functional Cargo in Exomeres |
| Dr. Qin Zhang, Vanderbilt University Medical Center |
| Consortium Member |
| 11 July 2019 |
| A related paper was published in the collection of ERCC1 papers at Cell Press. |
| Video not available. |
Improving experimental design to reveal EV functions: reprogramming gene expression in glioma and beyond |
| Dr. Anna Krichevsky, Brigham & Women’s Hospital, Dana-Farber/Harvard Cancer Center & HMS Initiative for RNA Medicine at Harvard Medical School |
| Consortium Member |
| 06 June 2019 |
| Video not available. |
Extracellular vesicle subpopulations – beyond exosomes and microvesicles |
| Dr. Jan Lotvall, University of Gothenberg |
| Guest Speaker |
| 04 April 2019 |
Miniaturized sensor systems for high-throughput EV analyses |
| Hakho Lee, Massachusetts General Hospital / Harvard Medical School Center for Systems Biology |
| Guest Speaker |
| 07 March 2019 |
| Video available after manuscript publication. |
The extracellular RNA-Seq processing pipeline of the ERCC and related tools |
| Joel Rozowsky, Yale University |
| Consortium member |
| 07 February 2019 |
Extracellular RNAs in populations and disease |
| Jane Freedman, University of Massachusetts Medical School |
| Consortium member |
| 03 January 2019 |
| Video not available. |
Infection and EVs: How an infected cell utilizes EVs to survive |
| Fatah Kashanchi, George Mason University |
| Guest speaker |
| 06 December 2018 |
| Video not available. |
Small RNA-seq of multiple biofluids |
| Kendall Jensen, Translational Genomics Research Institute |
| Consortium member |
| 01 November 2018 |
| Video not available. |
Blood-based assays for the diagnosis and stratification of glioma patients |
| Leonora Balaj, Deparment of Neurosurgery, Massaschusetts General Hospital |
| Consortium member |
| 04 October 2018 |
| Video not available. |
Regulation of immune response in colorectal cancer |
| Subbaya (Subree) Subramanian, University of Minnesota |
| Guest speaker |
| 12 July 2018 |
| Video not available. |
Comparison of exRNA isolation methods reveals that biofluids contain multiple distinct exRNA compartments |
| Srimeenakshi Srinivasan, UC San Diego Department of Reproductive Medicine |
| Consortium member |
| 07 June 2018 |
Circulating miRNAs and risk of Sudden Cardiac Death |
| Mike Silverman, Das lab, Massachusetts General Hospital |
| Consortium member |
| 10 May 2018 |
Arthropod exosomes as slingshots for transmission of tick and mosquito-borne flaviviruses |
| Hameeda Sultana, Old Dominion University |
| Guest speaker |
| 05 April 2018 |
Salivary exRNA and a new horizon in dental, oral and craniofacial biology |
| David Wong, UCLA |
| Consortium member |
| 01 March 2018 |
EVs as messengers of inflammation in HIV infection and cigarette use |
| Ken Witwer, Johns Hopkins |
| Guest speaker |
| 01 February 2018 |
Exosomes and exRNA: Modulating cellular transcriptome and regeneration |
| Susmita Sahoo, Icahn School of Medicine at Mount Sinai, NY |
| Guest speaker |
| 04 January 2018 |
Robust biomarker selection from RT-qPCR data using statistical consensus criteria |
| Jack Wiedrick, Oregon Health & Science University |
| Consortium member |
| 07 December 2017 |
KRAS-dependent sorting of miRNA into exosomes |
| James Patton, Vanderbilt |
| Consortium member |
| 05 October 2017 |
Aging affects extracellular RNA and extracellular vesicles |
| Nikki Noren Hooten, National Institute on Aging |
| Guest speaker |
| 07 September 2017 |
| See this related blog post. |
Extracellular RNA and vesicles in allergic lung inflammation |
| Heather Pua, Ansel lab, UCSF |
| Consortium member |
| 04 May 2017 |
MicroRNAs in cerebral spinal fluid as biomarker for Alzheimer’s disease |
| Julie Saugstad, Oregon Health Sciences University |
| Consortium member |
| 02 March 2017 |
| Video not available. |
Automated isolation and deep-sequencing characterization of nucleic acids from cell-free biofluids for clinical analysis |
| Tom Tuschl, Rockefeller University |
| Consortium member |
| 02 February 2017 |
Loading cancer drones: the regulation of exosomal non-coding RNA content by p53 |
| George Calin, MD Anderson Cancer Center |
| Consortium member |
| 01 December 2016 |
The distinct traits and functions of exosomes and microvesicles |
| Marc Antonyak, Cornell |
| Guest speaker |
| 27 October 2016 |
Cancer-host crosstalk through endogenous and exogenous extracellular miRNA |
| Emily Wang, UCSD |
| Guest speaker |
| 01 Sept 2016 |
Extracellular oncogenes as biological effectors and biomarkers |
| Janusz Rak, McGill University |
| Guest speaker |
| 30 June 2016 |
Overview of the first public release of the exRNA Atlas |
| Sai Lakshmi Subramanian, Baylor College of Medicine |
| Consortium member |
| 04 February 2016 |
Understanding and using small RNA-seq |
| David Galas, Pacific Northwest Diabetes Research Institute |
| Consortium member |
| 03 December 2015 |
