Kaczor-Urbanowicz KE et al.
Clinical validity of saliva and novel technology for cancer detection. Biochim Biophys Acta Rev Cancer (2019) 1872:49-59. Review Biomarkers
Petrescu GED et al.
MicroRNA based theranostics for brain cancer: Basic principles. J Exp Clin Cancer Res (2019) 38:231. Review Biomarkers Therapeutics
Watts JK, Brown RH & Khvorova A.
Nucleic acid therapeutics for neurological diseases. Neurotherapeutics (2019) 16:245-247. Review Therapeutics
Das S et al.
The Extracellular RNA Communication Consortium: Establishing foundational knowledge and technologies for extracellular RNA research. Cell (2019) 177:231-242. ERCC1 in Cell Press Review exRNA and EV Biology exRNA Biology
Bach DH, Lee SK & Sood AK.
Circular RNAs in Cancer. Mol Ther Nucleic Acids (2019) 16:118-129. Review exRNA Biology Biomarkers Therapeutics
Krichevsky AM & Uhlmann EJ.
Oligonucleotide therapeutics as a new class of drugs for malignant brain tumors: Targeting mRNAs, regulatory RNAs, mutations, combinations, and beyond. Neurotherapeutics (2019) 16:319-347. Review Therapeutics
Gulei D et al & .
CRISPR-based RNA editing: Diagnostic applications and therapeutic options. Expert Rev Mol Diagn (2019) 19:83-88. Review Biomarkers Therapeutics
Shah R, Patel T & Freedman JE.
Circulating extracellular vesicles in human disease. N Engl J Med (2018) 379:2180-2181. Review EV Biology
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system. Mol Ther Nucleic Acids (2018) 13:407-418. Review exRNA and EV Biology exRNA Biology Biomarkers
Moirangthem A & Patel T.
Mesenchymal stem cell derived extracellular vesicles: a promising new therapeutic approach for hepatic injury. Biotarget (2017) 1:12. Review exRNA and EV Biology EV Biology Therapeutics
Dragomir M, Chen B & Calin GA.
Exosomal lncRNAs as new players in cell-to-cell communication. Transl Cancer Res (2018) 7:S243-S252. Review exRNA and EV Biology
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis. Noncoding RNA Investig (2018) 2:43. Review exRNA and EV Biology exRNA Biology
Sung BH & Weaver AM.
Directed migration: Cells navigate by extracellular vesicles. J Cell Biol (2018) 217:2613-2614. Review exRNA and EV Biology EV Biology
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs. Front Oncol (2018) 8:179. Review exRNA and EV Biology exRNA Biology
Haemmerle M et al.
The platelet lifeline to cancer: Challenges and opportunities. Cancer Cell (2018) 33:965-983. Review exRNA and EV Biology EV Biology
Nonaka T & Wong DTW.
Liquid biopsy in head and neck cancer: Promises and challenges. J Dent Res (2018) 97:701-708. Review Biomarkers
Baecher-Allan C, Kaskow BJ & Weiner HL.
Multiple Sclerosis: Mechanisms and immunotherapy. Neuron (2018) 97:742-768. Review Biomarkers
Bei Y et al.
Extracellular vesicles in cardiovascular theranostics. Theranostics (2017) 7:4168-4182. Review Biomarkers Related Pathway
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones. Mol Oncol (2017) 11:1673-1686. Review exRNA and EV Biology exRNA Biology
Shankar GM et al.
Liquid biopsy for brain tumors. Expert Rev Mol Diagn (2017) 17:943-947. Review Biomarkers
Wu X et al & .
The many faces of long noncoding RNAs in cancer. Antioxid Redox Signal (2018) 29:922-935. Review Therapeutics
Ochocinska MJ et al.
NIH workshop report on the trans-agency Blood-Brain Interface Workshop 2016: Exploring key challenges and opportunities associated with the blood, brain and their interface. Fluids Barriers CNS (2017) 14:12. Review Therapeutics
Klingenberg M et al.
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets. J Hepatol (2017) 67:603-618. Review Biomarkers Related Pathways: 1, 2
Mateescu B et al.
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper. J Extracell Vesicles (2017) 6:1286095. Review Resources and Technology
Sutaria DS et al.
Achieving the promise of therapeutic extracellular vesicles: The devil is in details of therapeutic loading. Pharm Res (2017) 34:1053-1066. Review Therapeutics
Mick E et al.
Stroke and circulating extracellular RNAs. Stroke (2017) 48:828-834. Review Biomarkers
Nolan JP & Jones JC.
Detection of platelet vesicles by flow cytometry. Platelets (2017) 28:256-262. Review Resources and Technology
Grossman RL et al.
Collaborating to compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium. Clin Pharmacol Ther (2017) 101:589-592. Review Resources and Technology
Lee I et al.
The importance of standardization on analyzing circulating RNA. Mol Diagn Ther (2017) 21:259-268. Review Resources and Technology
Maji S et al.
Extracellular vesicles in liver diseases. Am J Physiol Gastrointest Liver Physiol (2017) 312:G194-G200. Review exRNA and EV Biology EV Biology
Maas SL, Breakefield XO & Weaver AM.
Extracellular vesicles: Unique intercellular delivery vehicles. Trends Cell Biol (2017) 27:172-188. Review exRNA and EV Biology EV Biology Therapeutics
Wang X, Kaczor-Urbanowicz KE & Wong DT.
Salivary biomarkers in cancer detection. Med Oncol (2017) 34:7. Review Biomarkers
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases. Best Pract Res Clin Endocrinol Metab (2016) 30:577-590. Review exRNA and EV Biology exRNA Biology Biomarkers Therapeutics
Kaczor-Urbanowicz KE et al.
Saliva diagnostics – Current views and directions. Exp Biol Med (Maywood) (2017) 242:459-472. Review Biomarkers
Kaczor-Urbanowicz KE et al.
Emerging technologies for salivaomics in cancer detection. J Cell Mol Med (2017) 21:640-647. Review Biomarkers
Nazimek K, Bryniarski K & Askenase PW.
Functions of exosomes and microbial extracellular vesicles in allergy and contact and delayed-type hypersensitivity. Int Arch Allergy Immunol (2016) 171:1-26. Review exRNA and EV Biology EV Biology
Shah MY et al.
microRNA therapeutics in cancer – an emerging concept. EBioMedicine (2016) 12:34-42. Review Therapeutics
Ghai V & Wang K.
Recent progress toward the use of circulating microRNAs as clinical biomarkers. Arch Toxicol (2016) 90:2959-2978. Review Biomarkers
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response. J Exp Clin Cancer Res (2016) 35:103. Review exRNA and EV Biology exRNA Biology Therapeutics
Srivastava A et al.
Exploitation of exosomes as nanocarriers for gene-, chemo-, and immune-therapy of cancer. J Biomed Nanotechnol (2016) 12:1159-73. Review Therapeutics
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation. Annu Rev Nutr (2016) 36:301-36. Review exRNA and EV Biology exRNA Biology
Abels ER & Breakefield XO.
Introduction to extracellular vesicles: Biogenesis, RNA cargo selection, content, release, and uptake. Cell Mol Neurobiol (2016) 36:301-12. Review exRNA and EV Biology EV Biology
Zappulli V et al.
Extracellular vesicles and intercellular communication within the nervous system. J Clin Invest (2016) 126:1198-207. Review exRNA and EV Biology EV Biology
Hall J et al.
Delivery of therapeutic proteins via extracellular vesicles: Review and potential treatments for Parkinson’s disease, glioma, and schwannoma. Cell Mol Neurobiol (2016) 36:417-27. Review Therapeutics
Parasramka MA et al.
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma. Pharmacol Ther (2016) 161:67-78. Review Therapeutics Related Pathway
Byron SA et al.
Translating RNA sequencing into clinical diagnostics: Opportunities and challenges. Nat Rev Genet (2016) 17:257-71. Related blog post Highly Cited (150+) Review Biomarkers
Rennert RC, Hochberg FH & Carter BS.
ExRNA in biofluids as biomarkers for brain tumors. Cell Mol Neurobiol (2016) 36:353-60. Review Biomarkers
Almeida MI & Calin GA.
The miR-143/miR-145 cluster and the tumor microenvironment: Unexpected roles. Genome Med (2016) 8:29. Review exRNA and EV Biology
Zaborowski MP et al.
Extracellular vesicles: Composition, biological relevance, and methods of study. Bioscience (2015) 65:783-797. Review exRNA and EV Biology Resources and Technology
Zhang X et al.
Potential transfer of polyglutamine and CAG-repeat RNA in extracellular vesicles in Huntington’s disease: Background and evaluation in cell culture. Cell Mol Neurobiol (2016) 36:459-70. Review exRNA and EV Biology EV Biology
Rupaimoole R et al.
miRNA deregulation in cancer cells and the tumor microenvironment. Cancer Discov (2016) 6:235-46. Review exRNA and EV Biology EV Biology
Melman YF et al.
Response to letter regarding article, “Circulating microRNA-30d is associated with response to cardiac resynchronization therapy in heart failure and regulates cardiomyocyte apoptosis: A translational pilot study” Circulation (2016) 133:e389-90. Review Biomarkers
Clancy L & Freedman JE.
Blood-derived extracellular RNA and platelet pathobiology: Adding pieces to a complex circulating puzzle. Circ Res (2016) 118:374-6. Review exRNA and EV Biology EV Biology
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers. Eur Urol (2016) 70:312-22. Review Biomarkers
Lener T et al.
Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper. J Extracell Vesicles (2015) 4:30087. Review Therapeutics
Machtinger R, Laurent LC & Baccarelli AA.
Extracellular vesicles: Roles in gamete maturation, fertilization and embryo implantation. Hum Reprod Update (2016) 22:182-93. Review exRNA and EV Biology EV Biology
Giza DE & Calin GA
microRNA and Chronic Lymphocytic Leukemia. Adv Exp Med Biol (2015) 889:23-40. Review exRNA and EV Biology exRNA Biology
Mohankumar S & Patel T.
Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer. Brief Funct Genomics (2016) 15:249-56. Review Biomarkers
Monroig-Bosque Pdel C, Rivera CA & Calin GA.
MicroRNAs in cancer therapeutics: “From the bench to the bedside”. Expert Opin Biol Ther (2015) 15:1381-5. Review Biomarkers
Quesenberry PJ et al.
Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium. J Extracell Vesicles (2015) 4:27575. Review Therapeutics
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium. J Extracell Vesicles (2015) 4:27493. Review exRNA and EV Biology exRNA Biology Biomarkers Therapeutics Resources and Technology
Quinn JF et al.
Extracellular RNAs: Development as biomarkers of human disease. J Extracell Vesicles (2015) 4:27495. Review Biomarkers
Laurent LC et al.
Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium. J Extracell Vesicles (2015) 4:26533. Review Biomarkers Resources and Technology
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA. J Extracell Vesicles (2015) 4:27494. Review exRNA and EV Biology exRNA Biology
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma. Curr Opin Immunol (2015) 36:101-8. Review exRNA and EV Biology exRNA Biology
Pichler M & Calin GA.
MicroRNAs in cancer: From developmental genes in worms to their clinical application in patients. Br J Cancer (2015) 113:569-73. Review exRNA and EV Biology exRNA Biology
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity. J Clin Invest (2015) 125:2242-9. Review exRNA and EV Biology exRNA Biology
Camussi G & Quesenberry PJ.
Perspectives on the potential therapeutic uses of vesicles. Exosomes Microvesicles (2013) 1:6. Review Therapeutics
Lin X et al.
Noncoding RNAs in human saliva as potential disease biomarkers. Front Genet (2015) 6:175. Review Biomarkers
Majem B et al.
Non-coding RNAs in saliva: Emerging biomarkers for molecular diagnostics. Int J Mol Sci (2015) 16:8676-98. Review Biomarkers
Nouraee N, Mowla SJ & Calin GA.
Tracking miRNAs’ footprints in tumor-microenvironment interactions: Insights and implications for targeted cancer therapy. Genes Chromosomes Cancer (2015) 54:335-52. Review exRNA and EV Biology
Non-coding RNAs in stroke and neuroprotection. Front Neurol (2015) 6:50. Review exRNA and EV Biology Biomarkers
Simonson B & Das S.
MicroRNA therapeutics: the next magic bullet? Mini Rev Med Chem (2015) 15:467-74. Review Therapeutics
Salivary extracellular noncoding RNA: Emerging biomarkers for molecular diagnostics. Clin Ther (2015) 37:540-51. Review Biomarkers
Xiao J et al.
A snapshot of genetic and epigenetic basis of arrhythmia and heart failure. Front Genet (2015) 6:74. Review Therapeutics
Gardiner C et al.
Extracellular vesicles, tissue factor, cancer and thrombosis – Discussion themes of the ISEV 2014 Educational Day. J Extracell Vesicles (2015) 4:26901. Review exRNA and EV Biology EV Biology
Ciccone M, Calin GA & Perrotti D.
From the biology of PP2A to the PADs for therapy of hematologic malignancies. Front Oncol (2015) 5:21. Review Therapeutics
A functional extracellular transcriptome in animals? Implications for biology, disease and medicine. Genome Biol (2015) 16:47. Review EV Biology Resources and Technology
Boukouris S & Mathivanan S.
Exosomes in bodily fluids are a highly stable resource of disease biomarkers. Proteomics Clin Appl (2015) 9:358-67. Review Biomarkers
George J & Patel T.
Noncoding RNA as therapeutic targets for hepatocellular carcinoma. Semin Liver Dis (2015) 35:63-74. Review Biomarkers Therapeutics
Srivastava A et al.
Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment. Curr Gene Ther (2015) 15:182-92. Review exRNA and EV Biology EV Biology Biomarkers Therapeutics
Lotvall J et al.
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. J Extracell Vesicles (2014) 3:26913. Review Resources and Technology
Berindan-Neagoe I & Calin GA.
Molecular pathways: microRNAs, cancer cells, and microenvironment. Clin Cancer Res (2014) 20:6247-53. Review exRNA and EV Biology exRNA Biology
Danielson KM & Das S.
Extracellular vesicles in heart disease: Excitement for the future? Exosomes Microvesicles (2014) 2:1. Review exRNA and EV Biology EV Biology Related Pathway
Fuentes L, Yakob M & Wong DT.
Emerging horizons of salivary diagnostics for periodontal disease. Br Dent J (2014) 217:567-73. Review Biomarkers
Rajendran L et al.
Emerging roles of extracellular vesicles in the nervous system. J Neurosci (2014) 34:15482-9. Review exRNA and EV Biology EV Biology
Sato-Kuwabara Y et al.
The fusion of two worlds: Non-coding RNAs and extracellular vesicles–Diagnostic and therapeutic implications. Int J Oncol (2015) 46:17-27. Review Biomarkers Therapeutics
Gangoda L et al.
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic? Proteomics (2015) 15:260-71. Review exRNA and EV Biology EV Biology Related Pathway
Kawikova I & Askenase PW.
Diagnostic and therapeutic potentials of exosomes in CNS diseases. Brain Res (2015) 1617:63-71. Review EV Biology Biomarkers Therapeutics
Godlewski J et al.
Belonging to a network–microRNAs, extracellular vesicles, and the glioblastoma microenvironment. Neuro Oncol (2015) 17:652-62. Review exRNA and EV Biology EV Biology
Gyorgy B et al.
Therapeutic applications of extracellular vesicles: Clinical promise and open questions. Annu Rev Pharmacol Toxicol (2015) 55:439-64. Highly Cited (200+) Review Therapeutics
Haga H & Patel T.
Molecular diagnosis of intrahepatic cholangiocarcinoma. J Hepatobiliary Pancreat Sci (2015) 22:114-23. Review Biomarkers
Braicu C et al.
Exosomes as divine messengers: Are they the Hermes of modern molecular oncology? Cell Death Differ (2015) 22:34-45. Review EV Biology Biomarkers
Thomas MF, L’Etoile ND & Ansel KM.
Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways. Trends Genet (2014) 30:298-307. Review exRNA and EV Biology Related Pathway
Yakob M et al.
Salivary biomarkers for detection of oral squamous cell carcinoma – Current state and recent advances. Curr Oral Health Rep (2014) 1:133-141. Review Biomarkers
Redzic JS et al.
Extracellular RNA mediates and marks cancer progression. Semin Cancer Biol (2014) 28:14-23. Review exRNA and EV Biology EV Biology Biomarkers
Quesenberry PJ et al.
Marrow hematopoietic stem cells revisited: They exist in a continuum and are not defined by standard purification approaches; Then there are the microvesicles. Front Oncol (2014) 4:56. Review exRNA and EV Biology EV Biology
Extracellular vesicle noncoding RNA: New players in the diagnosis and pathogenesis of cholangiocarcinoma. Hepatology (2014) 60:782-4. Review Biomarkers
Hochberg FH et al.
Glioma diagnostics and biomarkers: An ongoing challenge in the field of medicine and science. Expert Rev Mol Diagn (2014) 14:439-52. Review Biomarkers
Vader P, Breakefield XO & Wood MJ.
Extracellular vesicles: Emerging targets for cancer therapy. Trends Mol Med (2014) 20:385-393. Highly Cited (200+) Review Therapeutics
Quesenberry PJ et al.
Cellular phenotype and extracellular vesicles: Basic and clinical considerations. Stem Cells Dev (2014) 23:1429-36. Review exRNA and EV Biology EV Biology
Pusic AD, Pusic KM & Kraig RP.
What are exosomes and how can they be used in Multiple Sclerosis therapy? Expert Rev Neurother (2014) 14:353-5. Review Therapeutics
Takahashi K et al.
Long noncoding RNA in liver diseases. Hepatology (2014) 60:744-53. Review exRNA and EV Biology exRNA Biology Related Pathway
Clancy L & Freedman JE.
New paradigms in thrombosis: Novel mediators and biomarkers platelet RNA transfer. J Thromb Thrombolysis (2014) 37:12-6. Review exRNA and EV Biology exRNA Biology
Akers JC et al.
Biogenesis of extracellular vesicles (EV): Exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies. J Neurooncol (2013) 113:1-11. Highly Cited (400+) Review exRNA and EV Biology EV Biology
Quesenberry PJ et al.
A new stem cell biology: the continuum and microvesicles. Trans Am Clin Climatol Assoc (2012) 123:152-66. Review exRNA and EV Biology EV Biology
Gonda DD et al.
Neuro-oncologic applications of exosomes, microvesicles, and other nano-sized extracellular particles. Neurosurgery (2013) 72:501-10. Review exRNA and EV Biology EV Biology Biomarkers Therapeutics