The Extracellular RNA Communication Consortium has published 500+ research articles since its inception in 2013. Articles in the category “Reviews” are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Charest A.
Drula R et al.
Cancers (Basel) (2020) 12:2009.
Koupenova M & Freedman JE.
Platelets and immunity: Going viral.
Arterioscler Thromb Vasc Biol (2020) 40:1605-1607.
Zhang P et al.
Annu Rev Anal Chem (Palo Alto Calif) (2020) 13:17-43.
Yekula A et al.
O’Brien K et al.
RNA delivery by extracellular vesicles in mammalian cells and its applications.
Nat Rev Mol Cell Biol (2020) 21:585-606.
Tran AM et al.
Front Cell Dev Biol (2020) 8:50.
Wang C, Senapati S & Chang HC.
Electrophoresis AOP 2020-03-16.
Yekula A et al.
Extracellular vesicles in glioblastoma tumor microenvironment.
De Los Santos MC, Dragomir MP & Calin GA.
The role of exosomal long non-coding RNAs in cancer drug resistance.
Cancer Drug Resist (2019) 2:1178-1192.
Weaver AM & Patton JG.
Argonautes in extracellular vesicles: Artifact or selected cargo?
Pegtel DM & Gould SJ.
Annu Rev Biochem (2019) 88:487-514.
Kaczor-Urbanowicz KE et al.
Clinical validity of saliva and novel technology for cancer detection.
Biochim Biophys Acta Rev Cancer (2019) 1872:49-59.
Petrescu GED et al.
MicroRNA based theranostics for brain cancer: Basic principles.
J Exp Clin Cancer Res (2019) 38:231.
Wiklander OPB et al.
Advances in therapeutic applications of extracellular vesicles.
Bruno S et al.
Role of extracellular vesicles in stem cell biology.
Am J Physiol Cell Physiol (2019) 317:C303-C313.
Watts JK, Brown RH & Khvorova A.
Nucleic acid therapeutics for neurological diseases.
Neurotherapeutics (2019) 16:245-247.
Das S et al.
Schmittgen TD.
Exosomal miRNA cargo as mediator of immune escape mechanisms in neuroblastoma.
Cancer Res (2019) 79:1293-1294.
Bach DH, Lee SK & Sood AK.
Mol Ther Nucleic Acids (2019) 16:118-129.
Liu B et al.
Interplay between miRNAs and host genes and their role in cancer.
Brief Funct Genomics (2018) 18:255-266.
Krichevsky AM & Uhlmann EJ.
Neurotherapeutics (2019) 16:319-347.
Gulei D et al.
CRISPR-based RNA editing: Diagnostic applications and therapeutic options.
Expert Rev Mol Diagn (2019) 19:83-88.
LaFargue CJ et al.
Exploring and comparing adverse events between PARP inhibitors.
Lancet Oncol (2019) 20:e15-e28.
Shah R, Patel T & Freedman JE.
Circulating extracellular vesicles in human disease.
N Engl J Med (2018) 379:2180-2181.
Bei Y et al.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Moirangthem A & Patel T.
Dragomir M, Chen B & Calin GA.
Exosomal lncRNAs as new players in cell-to-cell communication.
Transl Cancer Res (2018) 7:S243-S252.
Raffai RL.
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis.
Noncoding RNA Investig (2018) 2:43.
Sung BH & Weaver AM.
Directed migration: Cells navigate by extracellular vesicles.
J Cell Biol (2018) 217:2613-2614.
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs.
Haemmerle M et al.
The platelet lifeline to cancer: Challenges and opportunities.
Cancer Cell (2018) 33:965-983.
Nonaka T & Wong DTW.
Liquid biopsy in head and neck cancer: Promises and challenges.
Baecher-Allan C, Kaskow BJ & Weiner HL.
Multiple Sclerosis: Mechanisms and immunotherapy.
Bei Y et al.
Extracellular vesicles in cardiovascular theranostics.
Theranostics (2017) 7:4168-4182.
Related Pathway
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones.
Mol Oncol (2017) 11:1673-1686.
Shankar GM et al.
Liquid biopsy for brain tumors.
Expert Rev Mol Diagn (2017) 17:943-947.
Wu X et al.
The many faces of long noncoding RNAs in cancer.
Antioxid Redox Signal (2018) 29:922-935.
Ochocinska MJ et al.
Fluids Barriers CNS (2017) 14:12.
Camarda R, Williams J & Goga A.
In vivo reprogramming of cancer metabolism by MYC.
Front Cell Dev Biol (2017) 5:35.
Klingenberg M et al.
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.
J Hepatol (2017) 67:603-618.
Related Pathways: 1, 2
Mateescu B et al.
J Extracell Vesicles (2017) 6:1286095.
Sutaria DS et al.
Pharm Res (2017) 34:1053-1066.
Mick E et al.
Stroke and circulating extracellular RNAs.
Nolan JP & Jones JC.
Detection of platelet vesicles by flow cytometry.
Grossman RL et al.
Collaborating to compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.
Clin Pharmacol Ther (2017) 101:589-592.
Lee I et al.
The importance of standardization on analyzing circulating RNA.
Mol Diagn Ther (2017) 21:259-268.
Maji S et al.
Extracellular vesicles in liver diseases.
Am J Physiol Gastrointest Liver Physiol (2017) 312:G194-G200.
Maas SL, Breakefield XO & Weaver AM.
Extracellular vesicles: Unique intercellular delivery vehicles.
Trends Cell Biol (2017) 27:172-188.
Wang X, Kaczor-Urbanowicz KE & Wong DT.
Salivary biomarkers in cancer detection.
Matsuda A et al.
MicroRNAs as paracrine signaling mediators in cancers and metabolic diseases.
Best Pract Res Clin Endocrinol Metab (2016) 30:577-590.
Kaczor-Urbanowicz KE et al.
Saliva diagnostics – Current views and directions.
Exp Biol Med (Maywood) (2017) 242:459-472.
Kaczor-Urbanowicz KE et al.
Emerging technologies for salivaomics in cancer detection.
J Cell Mol Med (2017) 21:640-647.
Nazimek K, Bryniarski K & Askenase PW.
Int Arch Allergy Immunol (2016) 171:1-26.
Shah MY et al.
microRNA therapeutics in cancer – an emerging concept.
Ghai V & Wang K.
Recent progress toward the use of circulating microRNAs as clinical biomarkers.
Arch Toxicol (2016) 90:2959-2978.
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Srivastava A et al.
Exploitation of exosomes as nanocarriers for gene-, chemo-, and immune-therapy of cancer.
J Biomed Nanotechnol (2016) 12:1159-73.
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation.
Annu Rev Nutr (2016) 36:301-36.
Abels ER & Breakefield XO.
Cell Mol Neurobiol (2016) 36:301-12.
Zappulli V et al.
Extracellular vesicles and intercellular communication within the nervous system.
J Clin Invest (2016) 126:1198-207.
Hall J et al.
Cell Mol Neurobiol (2016) 36:417-27.
Parasramka MA et al.
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma.
Pharmacol Ther (2016) 161:67-78.
Related Pathway
Byron SA et al.
Translating RNA sequencing into clinical diagnostics: Opportunities and challenges.
Nat Rev Genet (2016) 17:257-71. Related blog post
Rennert RC, Hochberg FH & Carter BS.
ExRNA in biofluids as biomarkers for brain tumors.
Cell Mol Neurobiol (2016) 36:353-60.
Almeida MI & Calin GA.
The miR-143/miR-145 cluster and the tumor microenvironment: Unexpected roles.
Zaborowski MP et al.
Extracellular vesicles: Composition, biological relevance, and methods of study.
Zhang X et al.
Cell Mol Neurobiol (2016) 36:459-70.
Rupaimoole R et al.
miRNA deregulation in cancer cells and the tumor microenvironment.
Cancer Discov (2016) 6:235-46.
Melman YF et al.
Circulation (2016) 133:e389-90.
Clancy L & Freedman JE.
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers.
Lener T et al.
Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper.
J Extracell Vesicles (2015) 4:30087.
Machtinger R, Laurent LC & Baccarelli AA.
Extracellular vesicles: Roles in gamete maturation, fertilization and embryo implantation.
Hum Reprod Update (2016) 22:182-93.
Giza DE & Calin GA
microRNA and Chronic Lymphocytic Leukemia.
Adv Exp Med Biol (2015) 889:23-40.
Mohankumar S & Patel T.
Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer.
Brief Funct Genomics (2016) 15:249-56.
Monroig-Bosque Pdel C, Rivera CA & Calin GA.
MicroRNAs in cancer therapeutics: “From the bench to the bedside”.
Expert Opin Biol Ther (2015) 15:1381-5.
Laurent LC et al.
J Extracell Vesicles (2015) 4:26533.
Quinn JF et al.
Extracellular RNAs: Development as biomarkers of human disease.
J Extracell Vesicles (2015) 4:27495.
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Quesenberry PJ et al.
J Extracell Vesicles (2015) 4:27575.
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma.
Curr Opin Immunol (2015) 36:101-8.
Pichler M & Calin GA.
MicroRNAs in cancer: From developmental genes in worms to their clinical application in patients.
Br J Cancer (2015) 113:569-73.
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity.
J Clin Invest (2015) 125:2242-9.
Camussi G & Quesenberry PJ.
Perspectives on the potential therapeutic uses of vesicles.
Exosomes Microvesicles (2013) 1:6.
Lin X et al.
Noncoding RNAs in human saliva as potential disease biomarkers.
Majem B et al.
Non-coding RNAs in saliva: Emerging biomarkers for molecular diagnostics.
Int J Mol Sci (2015) 16:8676-98.
Nouraee N, Mowla SJ & Calin GA.
Genes Chromosomes Cancer (2015) 54:335-52.
Saugstad JA.
Non-coding RNAs in stroke and neuroprotection.
Simonson B & Das S.
MicroRNA therapeutics: the next magic bullet?
Mini Rev Med Chem (2015) 15:467-74.
Wong DT.
Salivary extracellular noncoding RNA: Emerging biomarkers for molecular diagnostics.
Xiao J et al.
A snapshot of genetic and epigenetic basis of arrhythmia and heart failure.
Gardiner C et al.
J Extracell Vesicles (2015) 4:26901.
Ciccone M, Calin GA & Perrotti D.
From the biology of PP2A to the PADs for therapy of hematologic malignancies.
Tewari M.
A functional extracellular transcriptome in animals? Implications for biology, disease and medicine.
Boukouris S & Mathivanan S.
Exosomes in bodily fluids are a highly stable resource of disease biomarkers.
Proteomics Clin Appl (2015) 9:358-67.
George J & Patel T.
Noncoding RNA as therapeutic targets for hepatocellular carcinoma.
Semin Liver Dis (2015) 35:63-74.
Lotvall J et al.
J Extracell Vesicles (2014) 3:26913.
Srivastava A et al.
Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment.
Curr Gene Ther (2015) 15:182-92.
Berindan-Neagoe I & Calin GA.
Molecular pathways: microRNAs, cancer cells, and microenvironment.
Clin Cancer Res (2014) 20:6247-53.
Danielson KM & Das S.
Extracellular vesicles in heart disease: Excitement for the future?
Exosomes Microvesicles (2014) 2:1.
Related Pathway
Fuentes L, Yakob M & Wong DT.
Emerging horizons of salivary diagnostics for periodontal disease.
Rajendran L et al.
Emerging roles of extracellular vesicles in the nervous system.
Sato-Kuwabara Y et al.
Gangoda L et al.
Proteomics (2015) 15:260-71.
Related Pathway
Kawikova I & Askenase PW.
Diagnostic and therapeutic potentials of exosomes in CNS diseases.
Godlewski J et al.
Belonging to a network–microRNAs, extracellular vesicles, and the glioblastoma microenvironment.
Gyorgy B et al.
Therapeutic applications of extracellular vesicles: Clinical promise and open questions.
Annu Rev Pharmacol Toxicol (2015) 55:439-64.
Haga H & Patel T.
Molecular diagnosis of intrahepatic cholangiocarcinoma.
J Hepatobiliary Pancreat Sci (2015) 22:114-23.
Braicu C et al.
Exosomes as divine messengers: Are they the Hermes of modern molecular oncology?
Cell Death Differ (2015) 22:34-45.
Thomas MF, L’Etoile ND & Ansel KM.
Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.
Trends Genet (2014) 30:298-307.
Related Pathway
Yakob M et al.
Curr Oral Health Rep (2014) 1:133-141.
Redzic JS et al.
Extracellular RNA mediates and marks cancer progression.
Semin Cancer Biol (2014) 28:14-23.
Quesenberry PJ et al.
Patel T.
Hochberg FH et al.
Glioma diagnostics and biomarkers: An ongoing challenge in the field of medicine and science.
Expert Rev Mol Diagn (2014) 14:439-52.
Vader P, Breakefield XO & Wood MJ.
Extracellular vesicles: Emerging targets for cancer therapy.
Trends Mol Med (2014) 20:385-393.
Quesenberry PJ et al.
Cellular phenotype and extracellular vesicles: Basic and clinical considerations.
Stem Cells Dev (2014) 23:1429-36.
Pusic AD, Pusic KM & Kraig RP.
What are exosomes and how can they be used in Multiple Sclerosis therapy?
Expert Rev Neurother (2014) 14:353-5.
Takahashi K et al.
Long noncoding RNA in liver diseases.
Hepatology (2014) 60:744-53.
Related Pathway
Clancy L & Freedman JE.
New paradigms in thrombosis: Novel mediators and biomarkers platelet RNA transfer.
J Thromb Thrombolysis (2014) 37:12-6.
Akers JC et al.
Quesenberry PJ et al.
A new stem cell biology: the continuum and microvesicles.
Trans Am Clin Climatol Assoc (2012) 123:152-66.
Gonda DD et al.