Publications with Pathways

2018

Cortez MA et al.

Role of miRNAs in immune responses and immunotherapy in cancer.

Genes Chromosomes Cancer (2019) 58:244-253.
Related Pathway

Zhou S et al.

Chronic Platelet-derived Growth Factor Receptor signaling exerts control over initiation of protein translation in glioma.

Life Sci Alliance (2018) 1:e201800029.
Related Pathway

Jun HJ et al.

A PDGFRalpha-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.

Nat Commun (2018) 9:3116.
Related Pathway

Gharpure KM et al.

FABP4 as a key determinant of metastatic potential of ovarian cancer.

Nat Commun (2018) 9:2923.
Related Pathway

Koupenova M et al.

Circulating platelets as mediators of immunity, inflammation, and thrombosis.

Circ Res (2018) 122:337-351.
Related Pathway

Hulsmans M et al.

Cardiac macrophages promote diastolic dysfunction.

J Exp Med (2018) 215:423-440.
Related Pathway

2017

Leung CS et al.

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.

J Clin Invest (2018) 128:589-606.
Related Pathway

Vannini I et al.

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Nat Commun (2017) 8:1801.
Related Pathway

Bei Y et al.

Extracellular vesicles in cardiovascular theranostics.

Theranostics (2017) 7:4168-4182.
Review Biomarkers 
Related Pathway

Mitamura T et al.

Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).

Oncogene (2018) 37:722-731.
Related Pathway

Shen P et al.

To Wnt or lose: The missing non-coding linc in colorectal cancer.

Int J Mol Sci (2017) 18:9.
Related Pathway

Datta A et al.

Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.

Cancer Lett (2017) 408:73-81.
exRNA and EV Biology EV Biology 
Related Pathway

Klingenberg M et al.

Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.

J Hepatol (2017) 67:603-618.
Review Biomarkers 
Related Pathways: 1, 2

2016

Giza DE et al.

Cellular and viral microRNAs in sepsis: Mechanisms of action and clinical applications.

Cell Death Differ (2016) 23:1906-1918.
Related Pathway

Ciccone M & Calin GA.

MicroRNAs in chronic lymphocytic leukemia: An old disease with new genetic insights.

MicroRNA (2016) 5:106-112.
Related Pathway

Parasramka MA et al.

Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma.

Pharmacol Ther (2016) 161:67-78.
Review Therapeutics 
Related Pathway

2015

Shields BB et al.

A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.

Mol Syst Biol (2015) 11:842.
exRNA Biology Therapeutics 
Related Pathways: 1, 2

Wong HK et al.

The Cancer Genome Atlas analysis predicts microRNA for targeting cancer growth and vascularization in glioblastoma.

Mol Ther (2015) 23:1234-47.
Related Pathway

Li K et al.

Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.

Circ Res (2015) 117:e1-e11.
Related Pathway

Miyake TM et al.

XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A.

Clin Cancer Res (2015) 21:3286-97.
Related Pathway

Liu X et al.

miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.

Cell Metab (2015) 21:584-95.
Related Pathway

Gonzalez-Villasana V et al.

Rac1/Pak1/p38/MMP-2 axis regulates angiogenesis in ovarian cancer.

Clin Cancer Res (2015) 21:2127-37.
Therapeutics 
Related Pathway

2014

Danielson KM & Das S.

Extracellular vesicles in heart disease: Excitement for the future?

Exosomes Microvesicles (2014) 2:1.
Review exRNA and EV Biology EV Biology 
Related Pathway

van den Beucken T et al.

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

Nat Commun (2014) 5:5203.
Related Pathway

Gangoda L et al.

Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?

Proteomics (2015) 15:260-71.
Review exRNA and EV Biology EV Biology 
Related Pathway

Leung CS et al.

Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.

Nat Commun (2014) 5:5092.
Related Pathway

Han C et al.

The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression.

Cell Rep (2014) 8:1447-60.
Related Pathway

Krzeszinski JY et al.

MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.

Nature (2014) 512:431-5.
Highly Cited (300+) exRNA Biology Therapeutics 
Related Pathway

Thomas MF, L’Etoile ND & Ansel KM.

Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.

Trends Genet (2014) 30:298-307.
Review exRNA and EV Biology 
Related Pathway

Yang L et al.

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer.

Mol Syst Biol (2014) 10:728.
Related Pathway

Hu W et al.

Notch3 pathway alterations in ovarian cancer.

Cancer Res (2014) 74:3282-93.
Related Pathway

Takahashi K et al.

Long noncoding RNA in liver diseases.

Hepatology (2014) 60:744-53.
Review exRNA and EV Biology exRNA Biology 
Related Pathway

Beaulieu LM et al.

Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans.

Arterioscler Thromb Vasc Biol (2014) 34:552-64.
Related Pathway

Ozpolat B, Sood AK & Lopez-Berestein G.

Liposomal siRNA nanocarriers for cancer therapy.

Adv Drug Deliv Rev (2014) 66:110-6.
Highly Cited (250+) Therapeutics 
Related Pathway