Grant Project Page
Pusic KM, Kraig RP & Pusic AD.
IFNgamma-stimulated dendritic cell extracellular vesicles can be nasally administered to the brain and enter oligodendrocytes.
PLoS ONE (2021) 16:e0255778.
exRNA and EV Biology EV Biology Therapeutics Grant TR000918 Grant CA241703
Zheng JJ et al.
Isolation of HDL by sequential flotation ultracentrifugation followed by size exclusion chromatography reveals size-based enrichment of HDL-associated proteins.
Sci Rep (2021) 11:16086.
exRNA and EV Biology EV Biology Grant TR000918 Grant CA241694
Pusic KM et al.
Environmental enrichment and its benefits for migraine: Dendritic cell extracellular vesicles as an effective mimetic.
J Cell Immunol (2021) 3:215-225.
Review exRNA and EV Biology EV Biology Therapeutics Grant TR000918
IFNgamma-stimulated dendritic cell exosomes for treatment of migraine modeled using spreading depression.
Front Neurosci (2019) 13:942.
exRNA and EV Biology EV Biology Therapeutics Grant TR000918
Kaczor-Urbanowicz KE et al.
Novel approaches for bioinformatic analysis of salivary RNA sequencing data for development.
Bioinformatics (2018) 34:1-8.
Resources and Technology Grant TR000918 Grant TR000923
Grinberg YY, Zitzow LA & Kraig RP.
Intranasally administered IGF-1 inhibits spreading depression in vivo.
Brain Res (2017) 1677:47-57.
Grant TR000918
Ochocinska MJ et al.
NIH workshop report on the trans-agency Blood-Brain Interface Workshop 2016: Exploring key challenges and opportunities associated with the blood, brain and their interface.
Fluids Barriers CNS (2017) 14:12.
Review Therapeutics Grant TR000931 Grant TR000918
Rennert RC, Hochberg FH & Carter BS.
ExRNA in biofluids as biomarkers for brain tumors.
Cell Mol Neurobiol (2016) 36:353-60.
Review Biomarkers Grant TR000931 Grant TR000918
Pusic KM, Pusic AD & Kraig RP.
Environmental enrichment stimulates immune cell secretion of exosomes that promote CNS myelination and may regulate inflammation.
Cell Mol Neurobiol (2016) 36:313-325.
exRNA and EV Biology EV Biology Grant TR000918
Pusic AD & Kraig RP.
Phasic treatment with Interferon gamma stimulates release of exosomes that protect against spreading depression.
J Interferon Cytokine Res (2015) 35:795-807.
exRNA and EV Biology EV Biology Grant TR000918 Grant TR000943
Pusic AD et al.
Spreading depression transiently disrupts myelin via interferon-gamma signaling.
Exp Neurol (2015) 264:43-54.
Grant TR000918 Grant TR000943
Spreading depression requires microglia and is decreased by their M2a polarization from environmental enrichment.
Glia (2014) 62:1176-94.
Grant TR000918 Grant TR000884
Pusic AD, Pusic KM & Kraig RP.
What are exosomes and how can they be used in Multiple Sclerosis therapy?
Expert Rev Neurother (2014) 14:353-5.
Review Therapeutics Grant TR000918 Grant TR000906
Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination.
Glia (2014) 62:284-99.
exRNA and EV Biology Grant TR000918
IFNgamma-stimulated dendritic cell exosomes as a potential therapeutic for remyelination.
J Neuroimmunol (2014) 266:12-23.
Therapeutics Grant TR000918 Grant TR000921