Grant Project Page
Petrosyan V et al.
Immunologically “cold” triple negative breast cancers engraft at a higher rate in patient derived xenografts.
NPJ Breast Cancer (2022) 8:104.
Grant DA036134
Thistlethwaite LR et al.
CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models.
PLoS Comput Biol (2021) 17:e1008550.
Resources and Technology Grant DA036134 Grant DA049098
Lurie E et al.
Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin.
Oncogenesis (2020) 9:62.
Resources and Technology Grant DA036134
Lucero R et al.
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells.
Cell Rep (2020) 30:2065-2074.e4.
exRNA and EV Biology Grant CA179563 Grant TR000931 Grant DA036134
Lee J et al.
Rational design of a bifunctional AND-gate ligand to modulate cell-cell interactions.
ACS Synth Biol (2020) 9:191-197.
Grant DA036134 Grant HL126497
Kalra H et al.
Extracellular vesicles containing oncogenic mutant beta-catenin activate Wnt signalling pathway in the recipient cells.
J Extracell Vesicles (2019) 8:1690217.
exRNA and EV Biology EV Biology Grant DA036134
Carrero I et al.
Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments.
Oncogene (2019) 38:3551-3568.
Shen P et al.
Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling.
Mol Oncol (2018) 12:1856-1870.
Grant TR000943 Grant DA036134
Malabirade A et al.
The RNA complement of Outer Membrane Vesicles from Salmonella enterica Serovar Typhimurium under distinct culture conditions.
Front Microbiol (2018) 9:2015.
exRNA and EV Biology Grant TR000884 Grant DA036134 Grant HL126496
Onuchic V et al.
Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci.
Science (2018) 361:1354.
Shah R et al.
MicroRNAs associated with reverse left ventricular remodeling in humans identify pathways of heart failure progression.
Circ Heart Fail (2018) 11:e004278.
Biomarkers Grant TR000901 Grant DA036134
Reategui E et al.
Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Nat Commun (2018) 9:175.
Biomarkers Grant CA179563 Grant DA036134
Lankford KL et al.
Intravenously delivered mesenchymal stem cell-derived exosomes target M2-type macrophages in the injured spinal cord.
PLoS ONE (2018) 13:e0190358.
exRNA and EV Biology EV Biology Therapeutics Grant DA036134
Zhu X et al.
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.
J Extracell Vesicles (2017) 6:1324730.
Therapeutics Grant TR000914 Grant DA036134
Pathan M et al.
A novel community driven software for functional enrichment analysis of extracellular vesicles data.
J Extracell Vesicles (2017) 6:1321455.
Resources and Technology Grant TR000903 Grant DA036134
Haga H et al.
Extracellular vesicles from bone marrow-derived mesenchymal stem cells protect against murine hepatic ischemia/reperfusion injury.
Liver Transpl (2017) 23:791-803.
exRNA and EV Biology EV Biology Therapeutics Grant TR000884 Grant DA036134
Putman TE et al.
WikiGenomes: an open web application for community consumption and curation of gene annotation data in Wikidata.
Database (Oxford) (2017) 2017:1.
Previs RA et al.
The rise of genomic profiling in ovarian cancer.
Expert Rev Mol Diagn (2016) 16:1337-1351.
Nazimek K, Bryniarski K & Askenase PW.
Functions of exosomes and microbial extracellular vesicles in allergy and contact and delayed-type hypersensitivity.
Int Arch Allergy Immunol (2016) 171:1-26.
Review exRNA and EV Biology EV Biology Grant TR000903 Grant DA036134
Cheung KH et al.
Extending gene ontology in the context of extracellular RNA and vesicle communication.
J Biomed Semantics (2016) 7:19.
Resources and Technology Grant CA179512 Grant TR000906 Grant TR000880 Grant TR000914 Grant TR000884 Grant DA036134 Grant HL126494
Clarke D et al.
Identifying allosteric hotspots with dynamics: Application to inter- and intra-species conservation.
Structure (2016) 24:826-37.
Abels ER & Breakefield XO.
Introduction to extracellular vesicles: Biogenesis, RNA cargo selection, content, release, and uptake.
Cell Mol Neurobiol (2016) 36:301-12.
Highly Cited (550+) Review exRNA and EV Biology EV Biology Grant CA179563 Grant DA036134
Yan KK et al.
Cross-disciplinary network comparison: Matchmaking between hairballs.
Cell Syst (2016) 2:147-157.
Centralizing content and distributing labor: a community model for curating the very long tail of microbial genomes.
Database (Oxford) (2016) 2016:baw028.
Grant CA179563 Grant DA036134
Burgstaller-Muehlbacher S et al.
Wikidata as a semantic framework for the Gene Wiki initiative.
Database (Oxford) (2016) 2016:baw015.
Clancy L & Freedman JE.
Blood-derived extracellular RNA and platelet pathobiology: Adding pieces to a complex circulating puzzle.
Circ Res (2016) 118:374-6.
Review exRNA and EV Biology EV Biology Grant TR000921 Grant DA036134 Grant HL126495
Harmanci A & Gerstein M.
Quantification of private information leakage from phenotype-genotype data: linking attacks.
Nat Methods (2016) 13:251-6.
Askenase PW et al.
A subset of AID-dependent B-1a cells initiates hypersensitivity and pneumococcal pneumonia resistance.
Ann N Y Acad Sci (2015) 1362:200-14.
Yamamoto N et al.
Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: Evidence of a subpopulation of protective anti-pneumococcal B1a cells.
Immunology (2016) 147:97-113.
Grant TR000875 Grant DA036134
Zhuang X et al.
Grapefruit-derived nanovectors delivering therapeutic mir17 through an intranasal route inhibit brain tumor progression.
Mol Ther (2016) 24:96-105.
Therapeutics Grant TR000875 Grant DA036134
Keerthikumar S et al.
ExoCarta: A web-based compendium of exosomal cargo.
J Mol Biol (2016) 428:688-692.
Highly Cited (550+) Resources and Technology Grant DA036134
Bryniarski K et al.
Free extracellular miRNA functionally targets cells by transfecting exosomes from their companion cells.
PLoS ONE (2015) 10:e0122991.
exRNA and EV Biology EV Biology Grant TR000914 Grant DA036134
Nick AM et al.
A framework for a personalized surgical approach to ovarian cancer.
Nat Rev Clin Oncol (2015) 12:239-45.
Therapeutics Grant TR000943 Grant DA036134
Boukouris S & Mathivanan S.
Exosomes in bodily fluids are a highly stable resource of disease biomarkers.
Proteomics Clin Appl (2015) 9:358-67.
Review Biomarkers Grant CA179563 Grant DA036134
Gangoda L et al.
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
Proteomics (2015) 15:260-71.
Review exRNA and EV Biology EV Biology Grant DA036134
Related Pathway
Kawikova I & Askenase PW.
Diagnostic and therapeutic potentials of exosomes in CNS diseases.
Brain Res (2015) 1617:63-71.
Review EV Biology Biomarkers Therapeutics Grant CA179563 Grant DA036134
Haga H & Patel T.
Molecular diagnosis of intrahepatic cholangiocarcinoma.
J Hepatobiliary Pancreat Sci (2015) 22:114-23.
Review Biomarkers Grant TR000884 Grant DA036134
Kutmon M et al.
WikiPathways app for Cytoscape: Making biological pathways amenable to network analysis and visualization.
F1000Research (2014) 3:152.
Resources and Technology Grant TR000943 Grant DA036134
