Grant Project Page
Woodruff PG
Regulation of airway immunity by epithelial miRNAs.
Immunol Rev (2021) 304:141-153.
Review exRNA Biology Grant CA179512
Kilinc S et al.
Oncogene-regulated release of extracellular vesicles.
Dev Cell (2021) 56:1989-2006.e6.
exRNA and EV Biology EV Biology Grant CA179512
Tulpule A et al.
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules.
Cell (2021) 184:2649-2664.e18.
Grant CA179512 Grant HL126496
Bouchareychas L et al.
Macrophage exosomes resolve atherosclerosis by regulating hematopoiesis and inflammation via microRNA cargo.
Cell Rep (2020) 32:107881.
exRNA and EV Biology exRNA Biology EV Biology Therapeutics Grant CA179512 Grant CA179513
Duong P et al.
Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles.
PLoS One (2019) 14:e0215324.
Resources and Technology Grant CA179512
Belair CD et al.
High-throughput, efficient, and unbiased capture of small RNAs from low-input samples for sequencing.
Sci Rep (2019) 9:2262.
Pua HH et al.
Increased hematopoietic extracellular RNAs and vesicles in the lung during allergic airway responses.
Cell Rep (2019) 26:933-944.e4.
ERCC1 in Cell Press exRNA and EV Biology Biomarkers Grant CA179512
Chiou NT, Kageyama R & Ansel KM.
Selective export into extracellular vesicles and function of tRNa fragments during T cell activation.
Cell Rep (2018) 25:3356-3370.e4.
ERCC1 in Cell Press exRNA and EV Biology Grant CA179512
Jia N et al.
Type III-A CRISPR-Cas Csm complexes: Assembly, periodic RNA cleavage, DNase activity regulation, and autoimmunity.
Mol Cell (2019) 73:264-277.e5.
Grant CA179512 Grant CA179564
Chen B et al.
Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag.
Nat Commun (2018) 9:5065.
Grant CA179512
Monroig-Bosque PDC et al.
OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.
Sci Rep (2018) 8:13106.
Grant CA179512 Grant TR000943
Roy S et al.
microRNA 193a-5p regulates levels of Nucleolar- and Spindle-associated Protein 1 to suppress hepatocarcinogenesis.
Gastroenterology (2018) 155:1951-1966.e26.
Raffai RL.
MicroRNA-146a and hematopoiesis: Friend or foe in atherosclerosis.
Noncoding RNA Investig (2018) 2:43.
Review exRNA and EV Biology exRNA Biology Grant CA179512
Yan IK, Lohray R & Patel T.
Droplet digital PCR for quantitation of extracellular RNA.
Methods Mol Biol (2018) 1740:155-162.
Resources and Technology Grant CA179512 Grant TR000884
Li K et al.
Isolation of plasma lipoproteins as a source of extracellular RNA.
Methods Mol Biol (2018) 1740:139-153.
Cushioned-Density Gradient Ultracentrifugation (C-DGUC): A refined and high performance method for the isolation, characterization, and use of exosomes.
Methods Mol Biol (2018) 1740:69-83.
Viswanath P et al.
2-Hydroxyglutarate-mediated autophagy of the Endoplasmic Reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas.
Cancer Res (2018) 78:2290-2304.
Grant CA179512 Grant TR000921
Slenter DN et al.
WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research.
Nucleic Acids Res (2018) 46:D661-D667.
Highly Cited (400+) Resources and Technology Grant CA179512
Singh PB et al.
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.
J Exp Med (2017) 214:3627-3643.
Montoya MM et al.
A distinct inhibitory function for miR-18a in Th17 cell differentiation.
J Immunol (2017) 199:559-569.
Montoya MM & Ansel KM.
Small RNA transfection in primary human Th17 cells by next generation electroporation.
J Vis Exp (2017) 122:e55546.
Camarda R, Williams J & Goga A.
In vivo reprogramming of cancer metabolism by MYC.
Front Cell Dev Biol (2017) 5:35.
Review Grant CA179512 Grant TR000884
Yeo AT & Charest A.
Immune checkpoint blockade biology in mouse models of glioblastoma.
J Cell Biochem (2017) 118:2516-2527.
Grant CA179512 Grant CA179563
Anderton B et al.
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.
EMBO Rep (2017) 18:569-585.
Grant CA179512 Grant TR000901
Regev K et al.
Association between serum microRNAs and Magnetic Resonance Imaging measures of Multiple Sclerosis severity.
JAMA Neurol (2017) 74:275-285.
Biomarkers Grant CA179512 Grant TR000890
Ong WQ et al.
Live cell imaging of endogenous mRNA using RNA-based fluorescence “Turn-On” probe.
ACS Chem Biol (2017) 12:200-205.
Cheung KH et al.
Extending gene ontology in the context of extracellular RNA and vesicle communication.
J Biomed Semantics (2016) 7:19.
Resources and Technology Grant CA179512 Grant TR000906 Grant TR000880 Grant TR000914 Grant TR000884 Grant DA036134 Grant HL126494
Danielson KM et al.
Diurnal variations of circulating extracellular vesicles measured by nano flow cytometry.
PLoS ONE (2016) 11:e0144678.
Resources and Technology Grant CA179512 Grant HL126497
Quinn JF et al.
Extracellular RNAs: Development as biomarkers of human disease.
J Extracell Vesicles (2015) 4:27495.
Review Biomarkers Grant CA179512 Grant TR000903
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Review exRNA and EV Biology exRNA Biology Grant CA179512 Grant TR000901
Nagaraja AS et al.
Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis.
Oncogene (2016) 35:2390-7.
Pua HH & Ansel KM.
MicroRNA regulation of allergic inflammation and asthma.
Curr Opin Immunol (2015) 36:101-8.
Reyes-Gonzalez JM et al.
Targeting c-MYC in platinum-resistant ovarian cancer.
Mol Cancer Ther (2015) 14:2260-9.
Heavy water: a simple solution to increasing the brightness of fluorescent proteins in super-resolution imaging.
Chem Commun (Camb) (2015) 51:13451-3.
Szabo L et al.
Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.
Genome Biol (2015) 16:126.
Grant CA179512 Grant HL126494
Simpson LJ & Ansel KM.
MicroRNA regulation of lymphocyte tolerance and autoimmunity.
J Clin Invest (2015) 125:2242-9.
Review exRNA and EV Biology exRNA Biology Grant CA179512 Grant TR000880
Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.
Circ Res (2015) 117:e1-e11.
Grant CA179512 Grant TR000931
Related Pathway
Cox JE et al.
Pan-viral-microRNA screening identifies interferon inhibition as a common function of diverse viruses.
Proc Natl Acad Sci U S A (2015) 112:1856-61.
Murphy SJ et al.
Sex differences in microRNA expression during development in rat cortex.
Neurochem Int (2014) 77:24-32.
Thomas MF, L”Etoile ND & Ansel KM.
Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.
Trends Genet (2014) 30:298-307.
Review exRNA and EV Biology Grant CA179512 Grant TR000884
