Grant Project Page
Liu Q, Hsu CY & Shyr Y.
Scalable and model-free detection of spatial patterns and colocalization.
Genome Res (2022) 32:1736-1745.
Grant CA179514
Liu Q et al.
Dysregulated ligand-receptor interactions from single-cell transcriptomics.
Bioinformatics (2022) 38:3216-3221.
Grant CA179514 Grant DA049098
Barman B et al.
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites.
Dev Cell (2022) 57:974-994.e8.
exRNA and EV Biology exRNA Biology EV Biology Grant CA179514
Liu H et al.
Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression.
Mol Cancer (2022) 21:74.
Grant CA179514 Grant CA241684
Kaczor-Urbanowicz KE et al.
Reviews on current liquid biopsy for detection and management of pancreatic cancers.
Pancreas (2020) 49:1141-1152.
Review Resources and Technology Grant CA179514 Grant TR000923 Grant TR002978
Sung BH et al.
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells.
Nat Commun (2020) 11:2092.
exRNA and EV Biology EV Biology Resources and Technology Grant CA179514
Yokoi A et al.
Mechanisms of nuclear content loading to exosomes.
Sci Adv (2019) 5:eaax8849.
exRNA and EV Biology EV Biology Grant CA179514 Grant TR000943
Weaver AM & Patton JG.
Argonautes in extracellular vesicles: Artifact or selected cargo?
Cancer Res (2020) 80:379-381.
Review exRNA and EV Biology Grant CA179514
Zaborowski MP et al.
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.
Sci Rep (2019) 9:17387.
exRNA and EV Biology EV Biology Resources and Technology Grant CA179563 Grant CA179514
Sun L et al.
miR-302a inhibits metastasis and cetuximab resistance in colorectal cancer by targeting NFIB and CD44.
Theranostics (2019) 9:8409-8425.
exRNA and EV Biology exRNA Biology Biomarkers Therapeutics Grant CA179514
Zhang Q et al.
Transfer of functional cargo in exomeres.
Cell Rep (2019) 27:940-954.e6.
ERCC1 in Cell Press exRNA and EV Biology Resources and Technology Grant CA179514
Liu B et al.
Interplay between miRNAs and host genes and their role in cancer.
Brief Funct Genomics (2018) 18:255-266.
Review Grant CA179514
Jimenez L et al.
Quantitative proteomic analysis of small and large extracellular vesicles (EVs) reveals enrichment of adhesion proteins in small EVs.
J Proteome Res (2019) 18:947-959.
exRNA and EV Biology EV Biology Grant CA179514
Yu H et al.
beRBP: binding estimation for human RNA-binding proteins.
Nucleic Acids Res (2019) 47:e26.
Resources and Technology Grant CA179514
Hinger SA et al.
Diverse long RNAs are differentially sorted into extracellular vesicles secreted by colorectal cancer cells.
Cell Rep (2018) 25:715-725.e4.
ERCC1 in Cell Press exRNA and EV Biology Biomarkers Grant CA179514
Sung BH & Weaver AM.
Directed migration: Cells navigate by extracellular vesicles.
J Cell Biol (2018) 217:2613-2614.
Review exRNA and EV Biology EV Biology Grant CA179514
Mutant KRAS exosomes alter the metabolic state of recipient colonic epithelial cells.
Cell Mol Gastroenterol Hepatol (2018) 5:627-629.e6.
Gerstberger S et al.
The conserved RNA exonuclease Rexo5 is required for 3” end maturation of 28S rRNA, 5S rRNA, and snoRNAs.
Cell Rep (2017) 21:758-772.
Grant CA179514 Grant CA179564
Lu Y et al.
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/beta-catenin signaling.
Nat Med (2017) 23:1331-1341.
Maas SL, Breakefield XO & Weaver AM.
Extracellular vesicles: Unique intercellular delivery vehicles.
Trends Cell Biol (2017) 27:172-188.
Review exRNA and EV Biology EV Biology Therapeutics Grant CA179563 Grant CA179514 Grant TR000943
Katsiougiannis S et al.
Saliva exosomes from pancreatic tumor-bearing mice modulate NK cell phenotype and antitumor cytotoxicity.
FASEB J (2017) 31:998-1010.
exRNA and EV Biology EV Biology Therapeutics Grant CA179514 Grant TR000923
Dou Y et al.
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes.
Sci Rep (2016) 6:37982.
Biomarkers Grant CA179514
Higginbotham JN et al.
Identification and characterization of EGF receptor in individual exosomes by Fluorescence-Activated Vesicle Sorting.
J Extracell Vesicles (2016) 5:29254.
Resources and Technology Grant CA179514 Grant TR000943
Deng Z et al.
Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis.
Oncogene (2017) 36:639-651.
exRNA and EV Biology EV Biology Grant CA179514 Grant TR000875
Shah R et al.
Discordant expression of circulating microRNA from cellular and extracellular sources.
PLoS ONE (2016) 11:e0153691.
Resources and Technology Grant CA179514 Grant TR000921 Grant HL126495
McKenzie AJ et al.
KRAS-MEK signaling controls Ago2 sorting into exosomes.
Cell Rep (2016) 15:978-87.
exRNA and EV Biology EV Biology Grant CA179514 Grant TR000921
Cha DJ et al.
KRAS-dependent sorting of miRNA to exosomes.
Elife (2015) 4:e07197.
exRNA and EV Biology EV Biology Grant CA179514 Grant CA179564
Melman YF et al.
Circulating microRNA-30d is associated with response to cardiac resynchronization therapy in heart failure and regulates cardiomyocyte apoptosis: a translational pilot study.
Circulation (2015) 131:2202-16.
Biomarkers Grant CA179514 Grant TR000901
Directional cell movement through tissues is controlled by exosome secretion.
Nat Commun (2015) 6:7164.
Highly Cited (300+) exRNA and EV Biology EV Biology Grant CA179514