Grant Project Page
Tulpule A et al.
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules.
Cell (2021) 184:2649-2664.e18.
Grant CA179512 Grant HL126496
Kunert-Graf JM, Sakhanenko NA & Galas DJ.
Optimized permutation testing for information theoretic measures of multi-gene interactions.
BMC Bioinformatics (2021) 22:180.
Resources and Technology Grant HL126496
Ezzaty Mirhashemi M et al.
The dynamic platelet transcriptome in obesity and weight loss.
Arterioscler Thromb Vasc Biol (2021) 41:854-864.
Grant HL126495 Grant HL126496
Kunert-Graf J, Sakhanenko N & Galas D.
Partial information decomposition and the information delta: A geometric unification disentangling non-pairwise information.
Entropy (Basel) (2020) 22:1333.
Grant HL126496
Meabon JS et al.
Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure.
J Neurol Sci (2020) 417:117049.
Biomarkers Grant HL126496
Shukuya T et al.
Circulating microRNAs and extracellular vesicle-containing microRNAs as response biomarkers of Anti-programmed Cell Death Protein 1 or Programmed Death-Ligand 1 Therapy in NSCLC.
J Thorac Oncol (2020) 15:1773-1781.
Ghai V et al.
Alterations in plasma microRNA and protein levels in war veterans with chronic mild traumatic brain injury.
J Neurotrauma (2020) 37:1418-1430.
exRNA and EV Biology exRNA Biology Biomarkers Grant HL126496
Lee MJ et al.
The impact of Moyamoya disease and RNF213 mutations on the spectrum of plasma protein and microRNA.
J Clin Med (2019) 8:1648.
exRNA and EV Biology exRNA Biology Grant HL126496
Lee MY et al.
Distinct profiles of cell-free microRNAs in plasma of veterans with Post-Traumatic Stress Disorder.
J Clin Med (2019) 8:963.
exRNA and EV Biology Biomarkers Grant HL126496
A biological function based biomarker panel optimization process.
Sci Rep (2019) 9:7365.
Extracellular vesicle encapsulated microRNAs in patients with Type 2 Diabetes are affected by metformin treatment.
J Clin Med (2019) 8:617.
Biomarkers Therapeutics Grant HL126496
Giraldez MD et al.
Phospho-RNA-seq: a modified small RNA-seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma.
EMBO J (2019) 38:e101695.
Biomarkers Resources and Technology Grant HL126496 Grant HL126499
Circulating RNAs as predictive markers for the progression of type 2 diabetes.
J Cell Mol Med (2019) 23:2753-2768.
Malabirade A et al.
The RNA complement of Outer Membrane Vesicles from Salmonella enterica Serovar Typhimurium under distinct culture conditions.
Front Microbiol (2018) 9:2015.
exRNA and EV Biology Grant TR000884 Grant DA036134 Grant HL126496
Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.
Nat Biotechnol (2018) 36:746-757.
Resources and Technology Grant CA179563 Grant TR000891 Grant HL126493 Grant HL126494 Grant HL126495 Grant HL126496 Grant HL126497 Grant HL126499
Gyorgy B et al.
CRISPR/Cas9 mediated disruption of the Swedish APP allele as a therapeutic approach for early-onset Alzheimer”s disease.
Mol Ther Nucleic Acids (2018) 11:429-440.
Grant CA179563 Grant HL126496
Genome-wide profiling of urinary extracellular vesicle microRNAs associated with diabetic nephropathy in type 1 diabetes.
Kidney Int Rep (2018) 3:555-572.
Malge A et al.
mRNA transcript distribution bias between Borrelia burgdorferi bacteria and their outer membrane vesicles.
FEMS Microbiol Lett (2018) 365:13.
Heintz-Buschart A et al.
Small RNA profiling of low biomass samples: Identification and removal of contaminants.
BMC Biol (2018) 16:52.
Ricklefs FL et al.
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.
Sci Adv (2018) 4:eaar2766.
exRNA and EV Biology EV Biology Grant CA179563 Grant TR000931 Grant HL126496
Fallen S et al.
Extracellular vesicle RNAs reflect placenta dysfunction and are a biomarker source for preterm labour.
J Cell Mol Med (2018) 22:2760-2773.
Biomarkers Grant TR000923 Grant HL126496
Shukla N, Yan IK & Patel T.
Multiplexed detection and quantitation of extracellular vesicle RNA expression using NanoString.
Methods Mol Biol (2018) 1740:177-185.
Resources and Technology Grant TR000884 Grant HL126496
Etheridge A et al.
Preparation of small RNA NGS libraries from biofluids.
Methods Mol Biol (2018) 1740:163-175.
Nolan JP & Duggan E.
Analysis of individual extracellular vesicles by flow cytometry.
Methods Mol Biol (2018) 1678:79-92.
Resources and Technology Grant TR000931 Grant HL126496
Wu X et al.
sRNAnalyzer: a flexible and customizable small RNA sequencing data analysis pipeline.
Nucleic Acids Res (2017) 45:12140-12151.
Resources and Technology Grant HL126493 Grant HL126496
Wagner MJ et al.
Preclinical mammalian safety studies of EPHARNA (DOPC nanoliposomal EphA2-targeted siRNA).
Mol Cancer Ther (2017) 16:1114-1123.
Grant TR000943 Grant HL126496
He Y et al.
A systematic study of dysregulated microRNA in Type 2 Diabetes Mellitus.
Int J Mol Sci (2017) 18:3.
Biomarkers Grant TR000901 Grant HL126496
Danielson KM et al.
High throughput sequencing of extracellular RNA from human plasma.
PLoS ONE (2017) 12:e0164644.
Resources and Technology Grant TR000901 Grant HL126496
Lee I et al.
The importance of standardization on analyzing circulating RNA.
Mol Diagn Ther (2017) 21:259-268.
Review Resources and Technology Grant TR000884 Grant HL126496
Smith EM et al.
International validation of a urinary biomarker panel for identification of active lupus nephritis in children.
Pediatr Nephrol (2017) 32:283-295.
Biomarkers Grant CA179564 Grant HL126496
Ghai V & Wang K.
Recent progress toward the use of circulating microRNAs as clinical biomarkers.
Arch Toxicol (2016) 90:2959-2978.
Review Biomarkers Grant HL126496
Wu S et al.
Circulating microRNAs and life expectancy among identical twins.
Ann Hum Genet (2016) 80:247-56.
Fritz JV et al.
Sources and functions of extracellular small RNAs in human circulation.
Annu Rev Nutr (2016) 36:301-36.
Review exRNA and EV Biology exRNA Biology Grant CA179563 Grant HL126496
Henninger N et al.
Atrial fibrillation is associated with a worse 90-day outcome than other cardioembolic stroke subtypes.
Stroke (2016) 47:1486-92.
Grant TR000921 Grant HL126496
