Grant Project Page
Sundaram K et al.
Plant-derived exosomal nanoparticles inhibit pathogenicity of Porphyromonas gingivalis.
iScience (2019) 21:308-327.
exRNA and EV Biology EV Biology Therapeutics Grant TR000875
Wu D et al.
A plant pathogen Type III effector protein subverts translational regulation to boost host polyamine levels.
Cell Host Microbe (2019) 26:638-649.e5.
Grant TR000875 Grant CA241685
Axtell MJ.
Second to none: Plant secondary siRNAs as defensive agents against phytophthora.
Cell Host Microbe (2019) 25:7-9.
Review Grant TR000875
Usmani SM et al.
HIV-1 balances the fitness costs and benefits of disrupting the host cell actin cytoskeleton early after mucosal transmission.
Cell Host Microbe (2019) 25:73-86.e5.
Grant CA179563 Grant TR000875
Teng Y et al.
Plant-derived exosomal microRNAs shape the gut microbiota.
Cell Host Microbe (2018) 24:637-652.e8.
ERCC1 in Cell Press exRNA and EV Biology Therapeutics Grant TR000901 Grant TR000875
Wang QL et al.
Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways.
Theranostics (2018) 8:4912-4924.
exRNA and EV Biology Therapeutics Grant TR000875
Pi F et al.
Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression.
Nat Nanotechnol (2018) 13:82-89.
Therapeutics Grant TR000875
Piao X et al.
Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2”-F RNA, and LNA in the context of Phi29 pRNA 3WJ.
RNA (2018) 24:67-76.
Grant CA179564 Grant TR000875
Xiao J et al.
miR-31a-5p promotes postnatal cardiomyocyte proliferation by targeting RhoBTB1.
Exp Mol Med (2017) 49:e386.
Grant TR000901 Grant TR000875
Clancy L et al.
The role of RNA uptake in platelet heterogeneity.
Thromb Haemost (2017) 117:948-961.
exRNA and EV Biology EV Biology Grant TR000875 Grant TR000921 Grant HL126495
Deng Z et al.
Broccoli-derived nanoparticle inhibits mouse colitis by activating dendritic cell AMP-activated protein kinase.
Mol Ther (2017) 25:1641-1654.
ERCC1 in Cell Press exRNA and EV Biology EV Biology Therapeutics Grant TR000875
Haga H et al.
Extracellular vesicles from bone marrow-derived mesenchymal stem cells improve survival from lethal hepatic failure in mice.
Stem Cells Transl Med (2017) 6:1262-1272.
Therapeutics Grant TR000875 Grant TR000884
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression.
Nat Commun (2017) 8:14448.
exRNA and EV Biology EV Biology Grant TR000875 Grant HL126499
Wang JH et al.
Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug.
BMC Cancer (2016) 16:524.
Grant TR000902 Grant TR000875
Zhao Z et al.
An arginine finger regulates the sequential action of asymmetrical hexameric ATPase in the double-stranded DNA translocation motor.
Mol Cell Biol (2016) 36:2514-23.
Grant TR000943 Grant TR000875
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Review exRNA and EV Biology exRNA Biology Therapeutics Grant TR000943 Grant TR000875
Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis.
Oncogene (2017) 36:639-651.
exRNA and EV Biology EV Biology Grant CA179514 Grant TR000875
Zappulli V et al.
Extracellular vesicles and intercellular communication within the nervous system.
J Clin Invest (2016) 126:1198-207.
Review exRNA and EV Biology EV Biology Grant CA179563 Grant TR000875
Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages.
Oncotarget (2016) 7:25683-97.
Guo P et al.
Biological nanomotors with a revolution, linear, or rotation motion mechanism.
Microbiol Mol Biol Rev (2016) 80:161-86.
Zhuang X et al.
Ginger-derived nanoparticles protect against alcohol-induced liver damage.
J Extracell Vesicles (2015) 4:28713.
exRNA and EV Biology EV Biology Therapeutics Grant TR000875 Grant TR000891
Yamamoto N et al.
Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: Evidence of a subpopulation of protective anti-pneumococcal B1a cells.
Immunology (2016) 147:97-113.
Grant TR000875 Grant DA036134
Grapefruit-derived nanovectors delivering therapeutic mir17 through an intranasal route inhibit brain tumor progression.
Mol Ther (2016) 24:96-105.
Therapeutics Grant TR000875 Grant DA036134
Agarwal K et al.
Analysis of exosome release as a cellular response to MAPK pathway inhibition.
Langmuir (2015) 31:5440-8.
exRNA and EV Biology EV Biology Grant TR000914 Grant TR000875
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.
Nat Commun (2015) 6:6956.
exRNA and EV Biology EV Biology Grant TR000875
Majem B et al.
Non-coding RNAs in saliva: Emerging biomarkers for molecular diagnostics.
Int J Mol Sci (2015) 16:8676-98.
Review Biomarkers Grant TR000875 Grant TR000923
Wang Q et al.
Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites.
Cancer Res (2015) 75:2520-9.
Therapeutics Grant TR000943 Grant TR000875
Takahashi K et al.
Involvement of extracellular vesicle long non-coding RNA (linc-VLDLR) in tumor cell responses to chemotherapy.
Mol Cancer Res (2014) 12:1377-87.
exRNA and EV Biology EV Biology Grant TR000875 Grant TR000884
Mu J et al.
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles.
Mol Nutr Food Res (2014) 58:1561-73.
exRNA and EV Biology EV Biology Grant CA179563 Grant TR000875
Bauer CA et al.
Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction.
J Clin Invest (2014) 124:2425-40.
Jiang H et al.
Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2.
Cancer Immunol Res (2014) 2:789-99.
Grant TR000875
Vader P, Breakefield XO & Wood MJ.
Extracellular vesicles: Emerging targets for cancer therapy.
Trends Mol Med (2014) 20:385-393.
Highly Cited (250+) Review Therapeutics Grant CA179563 Grant TR000875
Quantitatively controlling expression of miR-17~92 determines colon tumor progression in a mouse tumor model.
Am J Pathol (2014) 184:1355-68.
Grant TR000880 Grant TR000875
Saugstad JA.
MicroRNAs as effectors of brain function.
Stroke (2013) 44:S17-9.
Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids.
Nat Commun (2013) 4:1867.
Deng ZB et al.
Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells.
J Immunol (2013) 190:3579-89.
exRNA and EV Biology EV Biology Grant TR000931 Grant TR000875