Grant Project Page
Park J et al.
An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma.
Nat Biomed Eng (2021) 5:678-689.
Resources and Technology Grant TR000931 Grant HL126499
Muralidharan K et al.
TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas.
Clin Cancer Res (2021) 27:169-178.
Biomarkers Grant TR000931 Grant CA241685
Yekula A et al.
Liquid biopsy strategies to distinguish progression from pseudoprogression and radiation necrosis in glioblastomas.
Adv Biosyst (2020) 4:e2000029.
Review Biomarkers Grant TR000931 Grant HL126494
Welsh JA et al.
MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments.
J Extracell Vesicles (2020) 9:1713526.
Resources and Technology Grant TR000931 Grant TR000891 Grant TR000903 Grant HL126497 Grant TR002881
Lucero R et al.
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells.
Cell Rep (2020) 30:2065-2074.e4.
exRNA and EV Biology Grant CA179563 Grant TR000931 Grant DA036134
Tosar JP & Cayota A.
Extracellular tRNAs and tRNA-derived fragments.
RNA Biol (2020) 17:1149-1167.
Review exRNA and EV Biology exRNA Biology Grant TR000931
From laboratory to clinic: Translation of extracellular vesicle based cancer biomarkers.
Methods (2020) 177:58-66.
Biomarkers Grant TR000931
Wei S et al.
A rapid and simple bead-bashing-based method for genomic DNA extraction from mammalian tissue.
Biotechniques (2020) 68:240-244.
Resources and Technology Grant TR000931 Grant CA179564
Amit M et al.
Loss of p53 drives neuron reprogramming in head and neck cancer.
Nature (2020) 578:449-454.
Therapeutics Grant TR000931
Extracellular vesicles in glioblastoma tumor microenvironment.
Front Immunol (2019) 10:3137.
Review exRNA and EV Biology EV Biology Grant TR000931
Roy S et al.
Navigating the landscape of tumor extracellular vesicle heterogeneity.
Int J Mol Sci (2019) 20:6.
exRNA and EV Biology EV Biology Grant TR000931
Ricklefs FL et al.
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.
Sci Adv (2018) 4:eaar2766.
exRNA and EV Biology EV Biology Grant CA179563 Grant TR000931 Grant HL126496
Nonaka T & Wong DTW.
Liquid biopsy in head and neck cancer: Promises and challenges.
J Dent Res (2018) 97:701-708.
Review Biomarkers Grant TR000931 Grant TR000923
Roy S, Hochberg FH & Jones PS.
Extracellular vesicles: the growth as diagnostics and therapeutics; a survey.
J Extracell Vesicles (2018) 7:1438720.
Review exRNA and EV Biology EV Biology Grant TR000931 Grant TR000902
Wei Z et al.
Coding and noncoding landscape of extracellular RNA released by human glioma stem cells.
Nat Commun (2017) 8:1145.
Biomarkers Resources and Technology Grant CA179563 Grant TR000931
Nolan JP & Duggan E.
Analysis of individual extracellular vesicles by flow cytometry.
Methods Mol Biol (2018) 1678:79-92.
Resources and Technology Grant TR000931 Grant HL126496
Rodriguez-Aguayo C et al.
Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.
Cell Discov (2017) 3:17029.
Grant TR000931 Grant TR000943
Shankar GM et al.
Liquid biopsy for brain tumors.
Expert Rev Mol Diagn (2017) 17:943-947.
Review Biomarkers Grant TR000931
Ochocinska MJ et al.
NIH workshop report on the trans-agency Blood-Brain Interface Workshop 2016: Exploring key challenges and opportunities associated with the blood, brain and their interface.
Fluids Barriers CNS (2017) 14:12.
Review Therapeutics Grant TR000931 Grant TR000918
Figueroa JM et al.
Detection of wtEGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients.
Neuro Oncol (2017) 19:1494-1502.
Nolan JP & Jones JC.
Detection of platelet vesicles by flow cytometry.
Platelets (2017) 28:256-262.
Review Resources and Technology Grant TR000931 Grant HL126495 Grant HL126497
Haemmerle M et al.
FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.
J Clin Invest (2016) 126:1885-96.
Akers JC et al.
Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid.
Cancer Biomark (2016) 17:125-32.
Resources and Technology Grant CA179563 Grant TR000931
Huang J et al.
Dll4 inhibition plus aflibercept markedly reduces ovarian tumor growth.
Mol Cancer Ther (2016) 15:1344-52.
Byron SA et al.
Translating RNA sequencing into clinical diagnostics: Opportunities and challenges.
Nat Rev Genet (2016) 17:257-71. Related blog post
Highly Cited (350+) Review Biomarkers Grant TR000931
Rennert RC, Hochberg FH & Carter BS.
ExRNA in biofluids as biomarkers for brain tumors.
Cell Mol Neurobiol (2016) 36:353-60.
Review Biomarkers Grant TR000931 Grant TR000918
miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients.
J Neurooncol (2015) 123:205-16.
Biomarkers Grant CA179563 Grant TR000931
Li K et al.
Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.
Circ Res (2015) 117:e1-e11.
Grant CA179512 Grant TR000931
Related Pathway
Schwarzenbacher D et al.
Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget (2015) 6:11191-202.
Gilder AS et al.
Soluble Urokinase Receptor is released selectively by glioblastoma cells that express Epidermal Growth Factor Receptor variant III and promotes tumor cell migration and invasion.
J Biol Chem (2015) 290:14798-809.
Xiao J et al.
A snapshot of genetic and epigenetic basis of arrhythmia and heart failure.
Front Genet (2015) 6:74.
Review Therapeutics Grant TR000931 Grant TR000901
Gardiner C et al.
Extracellular vesicles, tissue factor, cancer and thrombosis – Discussion themes of the ISEV 2014 Educational Day.
J Extracell Vesicles (2015) 4:26901.
Hochberg FH et al.
Glioma diagnostics and biomarkers: An ongoing challenge in the field of medicine and science.
Expert Rev Mol Diagn (2014) 14:439-52.
Review Biomarkers Grant TR000931 Grant TR000943
Yao C et al.
Sex- and age-interacting eQTLs in human complex diseases.
Hum Mol Genet (2014) 23:1947-56.
Grant TR000931 Grant TR000921
MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.
PLoS ONE (2013) 8:e78115.
Chen WW et al.
BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles.
Mol Ther Nucleic Acids (2013) 2:e109.
Biomarkers Resources and Technology Grant TR000931 Grant TR000923
Deng ZB et al.
Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells.
J Immunol (2013) 190:3579-89.
exRNA and EV Biology EV Biology Grant TR000931 Grant TR000875
Biogenesis of extracellular vesicles (EV): Exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies.
J Neurooncol (2013) 113:1-11.
Highly Cited (750+) Review exRNA and EV Biology EV Biology Grant TR000931 Grant TR000880
Quesenberry PJ et al.
A new stem cell biology: the continuum and microvesicles.
Trans Am Clin Climatol Assoc (2012) 123:152-66.
Review exRNA and EV Biology EV Biology Grant TR000931 Grant TR000880
Gonda DD et al.
Neuro-oncologic applications of exosomes, microvesicles, and other nano-sized extracellular particles.
Neurosurgery (2013) 72:501-10.
Review exRNA and EV Biology EV Biology Biomarkers Therapeutics Grant CA179563 Grant TR000931
