Grant Project Page
Crouser ED et al.
Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia.
PLoS ONE (2021) 16:e0246083.
Biomarkers Grant HL126495 Grant TR002884
Palace SG et al.
Yersinia pestis escapes entrapment in thrombi by targeting platelet function.
J Thromb Haemost (2020) 18:3236-3248.
Grant TR000921 Grant HL126495
Ezzaty Mirhashemi M et al.
The dynamic platelet transcriptome in obesity and weight loss.
Arterioscler Thromb Vasc Biol (2021) 41:854-864.
Grant HL126495 Grant HL126496
Koupenova M & Freedman JE.
Platelets and immunity: Going viral.
Arterioscler Thromb Vasc Biol (2020) 40:1605-1607.
Review exRNA and EV Biology EV Biology Grant TR000921 Grant HL126495
Hunter-Zinck H et al.
Genotyping array design and data quality control in the Million Veteran Program.
Am J Hum Genet (2020) 106:535-548.
Resources and Technology Grant HL126495 Grant CA241694
Koupenova M et al.
The role of platelets in mediating a response to human influenza infection.
Nat Commun (2019) 10:1780.
Shah R, Murthy V & Freedman JE.
Nuts, cardiovascular health, and diabetes.
Circ Res (2019) 124:825-826.
Shah RV et al.
Proteins altered by surgical weight loss highlight biomarkers of insulin resistance in the community.
Arterioscler Thromb Vasc Biol (2019) 39:107-115.
Kanlikilicer P et al.
Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer.
EBioMedicine (2018) 38:100-112.
ERCC1 in Cell Press exRNA and EV Biology Therapeutics Grant HL126495
Shah R, Patel T & Freedman JE.
Circulating extracellular vesicles in human disease.
N Engl J Med (2018) 379:2180-2181.
Review EV Biology Grant HL126495
Moirangthem A & Patel T.
Mesenchymal stem cell derived extracellular vesicles: a promising new therapeutic approach for hepatic injury.
Biotarget (2017) 1:12.
Review exRNA and EV Biology EV Biology Therapeutics Grant TR000884 Grant HL126495
Narla V et al.
Unique circulating microRNA profiles in HIV infection.
J Acquir Immune Defic Syndr (2018) 79:644-650.
Biomarkers Grant TR000921 Grant HL126495
Associations of circulating extracellular RNAs with myocardial remodeling and heart failure.
JAMA Cardiol (2018) 3:871-876.
Biomarkers Grant TR000901 Grant TR000921 Grant HL126495
Giraldez MD et al.
Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.
Nat Biotechnol (2018) 36:746-757.
Resources and Technology Grant CA179563 Grant TR000891 Grant HL126493 Grant HL126494 Grant HL126495 Grant HL126496 Grant HL126497 Grant HL126499
Mick E et al.
Stroke and circulating extracellular RNAs.
Stroke (2017) 48:828-834.
Review Biomarkers Grant TR000921 Grant HL126495
Clancy L et al.
The role of RNA uptake in platelet heterogeneity.
Thromb Haemost (2017) 117:948-961.
exRNA and EV Biology EV Biology Grant TR000875 Grant TR000921 Grant HL126495
Nolan JP & Jones JC.
Detection of platelet vesicles by flow cytometry.
Platelets (2017) 28:256-262.
Review Resources and Technology Grant TR000931 Grant HL126495 Grant HL126497
Shah R, Pico AR & Freedman JE.
Translational epidemiology: Entering a brave new world of team science.
Circ Res (2016) 119:1060-1062.
Shah R et al.
Discordant expression of circulating microRNA from cellular and extracellular sources.
PLoS ONE (2016) 11:e0153691.
Resources and Technology Grant CA179514 Grant TR000921 Grant HL126495
Freedman JE et al.
Diverse human extracellular RNAs are widely detected in human plasma.
Nat Commun (2016) 7:11106.
Resources and Technology Grant TR000921 Grant TR000884 Grant HL126495
Tanriverdi K et al.
Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative Polymerase Chain Reaction.
Anal Biochem (2016) 501:66-74.
Resources and Technology Grant TR000943 Grant TR000921 Grant HL126495
Clancy L & Freedman JE.
Blood-derived extracellular RNA and platelet pathobiology: Adding pieces to a complex circulating puzzle.
Circ Res (2016) 118:374-6.
Review exRNA and EV Biology EV Biology Grant TR000921 Grant DA036134 Grant HL126495
Huan T et al.
Genome-wide identification of microRNA expression Quantitative Trait Loci.
Nat Commun (2015) 6:6601.
Grant TR000901 Grant TR000921 Grant HL126495
Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors.
Arterioscler Thromb Vasc Biol (2015) 35:1030-7.
Grant TR000921 Grant TR000923 Grant HL126495
Yao C et al.
Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.
Circulation (2015) 131:536-49.
Grant TR000943 Grant TR000921 Grant HL126495
