Grant Project Page
Li J et al.
Angiotensin II-induced muscle atrophy via PPARgamma suppression is mediated by miR-29b.
Mol Ther Nucleic Acids (2021) 23:743-756.
Grant TR000901
Gorur A et al.
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer.
Mol Ther Nucleic Acids (2021) 23:930-943.
Therapeutics Grant TR000901 Grant TR000943
Silverman MG et al.
Circulating miRNAs and risk of sudden death in patients with coronary heart disease.
JACC Clin Electrophysiol (2020) 6:70-79.
Biomarkers Therapeutics Grant TR000901
Divakaran S et al.
Diagnostic accuracy of advanced imaging in cardiac sarcoidosis.
Circ Cardiovasc Imaging (2019) 12:e008975.
Zelniker TA et al.
Biomarker of collagen turnover (C-terminal telopeptide) and prognosis in patients with non-ST-elevation acute coronary syndromes.
J Am Heart Assoc (2019) 8:e011444.
Grani C et al.
Comparison of myocardial fibrosis quantification methods by cardiovascular magnetic resonance imaging for risk stratification of patients with suspected myocarditis.
J Cardiovasc Magn Reson (2019) 21:14.
Bei Y et al.
Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury.
BMC Med (2019) 17:42.
Teng Y et al.
Plant-derived exosomal microRNAs shape the gut microbiota.
Cell Host Microbe (2018) 24:637-652.e8.
ERCC1 in Cell Press exRNA and EV Biology Therapeutics Grant TR000901 Grant TR000875
Vita T et al.
Comparing CMR mapping methods and myocardial patterns toward heart failure outcomes in nonischemic dilated cardiomyopathy.
JACC Cardiovasc Imaging (2019) 12:1659-1669.
Circular RNAs as potential theranostics in the cardiovascular system.
Mol Ther Nucleic Acids (2018) 13:407-418.
Review exRNA and EV Biology exRNA Biology Biomarkers Grant TR000901
Shah RV et al.
Associations of circulating extracellular RNAs with myocardial remodeling and heart failure.
JAMA Cardiol (2018) 3:871-876.
Biomarkers Grant TR000901 Grant TR000921 Grant HL126495
Dluzen DF et al.
Extracellular RNA profiles with human age.
Aging Cell (2018) 17:e12785.
exRNA Biology Resources and Technology Grant TR000901
Danielson KM et al.
Plasma circulating extracellular RNAs in Left Ventricular Remodeling post-Myocardial Infarction.
EBioMedicine (2018) 32:172-181.
ERCC1 in Cell Press exRNA and EV Biology exRNA Biology Biomarkers Grant TR000901 Grant TR000923
Yeri A et al.
Evaluation of commercially available small RNASeq library preparation kits using low input RNA.
BMC Genomics (2018) 19:331.
Resources and Technology Grant TR000901 Grant TR000891
Vujic A et al.
Exercise induces new cardiomyocyte generation in the adult mammalian heart.
Nat Commun (2018) 9:1659.
exRNA and EV Biology exRNA Biology Resources and Technology Grant TR000901
Shah R et al.
MicroRNAs associated with reverse left ventricular remodeling in humans identify pathways of heart failure progression.
Circ Heart Fail (2018) 11:e004278.
Biomarkers Grant TR000901 Grant DA036134
Filant J et al.
Isolation of extracellular RNA from serum/plasma.
Methods Mol Biol (2018) 1740:43-57.
Resources and Technology Grant TR000901 Grant TR000906 Grant TR000943 Grant TR000890 Grant HL126494
Hulsmans M et al.
Cardiac macrophages promote diastolic dysfunction.
J Exp Med (2018) 215:423-440.
Grant CA179563 Grant TR000901
Related Pathway
Lu Y et al.
MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels.
Cancer Res (2018) 78:64-74.
Grant TR000901 Grant TR000943
Extracellular vesicles in cardiovascular theranostics.
Theranostics (2017) 7:4168-4182.
Review Biomarkers Grant TR000901
Nonaka T & Wong DTW.
Saliva exosomics in cancer: Molecular characterization of cancer-derived exosomes in saliva.
Enzymes (2017) 42:125-151.
exRNA and EV Biology EV Biology Grant TR000901 Grant TR000923
Xiao J et al.
miR-31a-5p promotes postnatal cardiomyocyte proliferation by targeting RhoBTB1.
Exp Mol Med (2017) 49:e386.
Grant TR000901 Grant TR000875
Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: Brief report.
Am J Physiol Heart Circ Physiol (2017) 313:H1162-H1167.
exRNA Biology Biomarkers Grant TR000901 Grant CA179513 Grant HL126497
Datta A et al.
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
Cancer Lett (2017) 408:73-81.
exRNA and EV Biology EV Biology Grant TR000928 Grant TR000901
Jones A et al.
miRNA signatures of insulin resistance in obesity.
Obesity (2017) 25:1734-1744.
Biomarkers Grant TR000901
Aldrugh S et al.
Atrial fibrillation, cognition and dementia: A review.
J Cardiovasc Electrophysiol (2017) 28:958-965.
Grant TR000901 Grant TR000921
miR-29b contributes to multiple types of muscle atrophy.
Nat Commun (2017) 8:15201.
Rigoutsos I et al.
N-BLR, a primate-specific non-coding transcript, leads to colorectal cancer invasion and migration.
Genome Biol (2017) 18:98.
Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury.
Basic Res Cardiol (2017) 112:38.
exRNA and EV Biology EV Biology Therapeutics Grant TR000901 Grant CA179513 Grant HL126497
Roh J, Houstis N & Rosenzweig A.
Why don”t we have proven treatments for HFpEF?
Circ Res (2017) 120:1243-1245.
Grant TR000901 Grant TR000884
Soni A et al.
RAHI-SATHI Indo-U.S. collaboration: The evolution of a trainee-led twinning model in global health into a multidisciplinary collaborative program.
Glob Health Sci Pract (2017) 5:152-163.
Mateescu B et al.
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper.
J Extracell Vesicles (2017) 6:1286095.
Highly Cited (350+) Review Resources and Technology Grant TR000901
He Y et al.
A systematic study of dysregulated microRNA in Type 2 Diabetes Mellitus.
Int J Mol Sci (2017) 18:3.
Biomarkers Grant TR000901 Grant HL126496
Shi J et al.
miR-17-3p contributes to exercise-induced cardiac growth and protects against myocardial ischemia-reperfusion injury.
Theranostics (2017) 7:664-676.
Grant TR000888 Grant TR000901
Anderton B et al.
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.
EMBO Rep (2017) 18:569-585.
Grant CA179512 Grant TR000901
Circulating miR-30d predicts survival in patients with acute heart failure.
Cell Physiol Biochem (2017) 41:865-874.
Biomarkers Grant TR000901 Grant TR000884
Grossman RL et al.
Collaborating to compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.
Clin Pharmacol Ther (2017) 101:589-592.
Review Resources and Technology Grant TR000901 Grant HL126499
Extracellular RNAs are associated with insulin resistance and metabolic phenotypes.
Diabetes Care (2017) 40:546-553.
Collino F et al.
Exosome and microvesicle-enriched fractions isolated from mesenchymal stem cells by gradient separation showed different molecular signatures and functions on renal tubular epithelial cells.
Stem Cell Rev (2017) 13:226-243.
exRNA and EV Biology EV Biology Grant TR000901 Grant TR000880
Heydari B, Harris WS & Kwong RY.
Response by Heydari et al to letter regarding article, “Effect of omega-3 acid ethyl esters on left ventricular remodeling after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial”.
Circulation (2017) 135:e13-e14.
High throughput sequencing of extracellular RNA from human plasma.
PLoS ONE (2017) 12:e0164644.
Resources and Technology Grant TR000901 Grant HL126496
Shah MY et al.
microRNA therapeutics in cancer – an emerging concept.
EBioMedicine (2016) 12:34-42.
Review Therapeutics Grant TR000901 Grant TR000943
Tao L et al.
Crucial role of miR-433 in regulating cardiac fibrosis.
Theranostics (2016) 6:2068-2083.
Maji S et al.
In vitro toxicology studies of extracellular vesicles.
J Appl Toxicol (2017) 37:310-318.
Therapeutics Grant TR000901 Grant TR000884
Bezzerides VJ et al.
CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury.
JCI Insight (2016) 1:9.
Wang JQ et al.
Extracellular vesicle-mediated reversal of paclitaxel resistance in prostate cancer.
Crit Rev Oncog (2015) 20:407-17.
exRNA and EV Biology EV Biology Therapeutics Grant TR000901 Grant TR000880
Freedman JE et al.
Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma.
Nat Commun (2016) 7:11902.
Resources and Technology Grant TR000901 Grant TR000921
Sun Y et al.
Examining plasma microRNA markers for colorectal cancer at different stages.
Oncotarget (2016) 7:11434-49.
Biomarkers Grant TR000901 Grant TR000943
Melman YF et al.
Response to letter regarding article, “Circulating microRNA-30d is associated with response to cardiac resynchronization therapy in heart failure and regulates cardiomyocyte apoptosis: A translational pilot study”
Circulation (2016) 133:e389-90.
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers.
Eur Urol (2016) 70:312-22.
Review Biomarkers Grant TR000901 Grant TR000943
Xu T et al.
Circulating miR-21, miR-378, and miR-940 increase in response to an acute exhaustive exercise in chronic heart failure patients.
Oncotarget (2016) 7:12414-25.
Biomarkers Grant TR000901 Grant TR000884 Grant HL126497
Ainsztein AM et al.
The NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:27493.
Review exRNA and EV Biology exRNA Biology Biomarkers Therapeutics Resources and Technology Grant TR000901
Laurent LC et al.
Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:26533.
Review Biomarkers Resources and Technology Grant TR000901 Grant TR000943
Patton JG et al.
Biogenesis, delivery, and function of extracellular RNA.
J Extracell Vesicles (2015) 4:27494.
Review exRNA and EV Biology exRNA Biology Grant CA179512 Grant TR000901
Aslan B et al.
The ZNF304-integrin axis protects against anoikis in cancer.
Nat Commun (2015) 6:7351.
Kwong RY et al.
Characterization of cardiac amyloidosis by atrial late gadolinium enhancement using contrast-enhanced cardiac Magnetic Resonance Imaging and correlation with left atrial conduit and contractile function.
Am J Cardiol (2015) 116:622-9.
Grant TR000901 Grant HL126494
Lin X et al.
Noncoding RNAs in human saliva as potential disease biomarkers.
Front Genet (2015) 6:175.
Review Biomarkers Grant TR000901 Grant TR000923
Circulating microRNA-30d is associated with response to cardiac resynchronization therapy in heart failure and regulates cardiomyocyte apoptosis: a translational pilot study.
Circulation (2015) 131:2202-16.
Biomarkers Grant CA179514 Grant TR000901
Miyake TM et al.
XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A.
Clin Cancer Res (2015) 21:3286-97.
Liu X et al.
miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.
Cell Metab (2015) 21:584-95.
Ren A et al.
Structural basis for molecular discrimination by a 3”,3”-cGAMP sensing riboswitch.
Cell Rep (2015) 11:1-12.
Grant TR000901 Grant CA179564
Simonson B & Das S.
MicroRNA therapeutics: the next magic bullet?
Mini Rev Med Chem (2015) 15:467-74.
Ling H et al.
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
Gut (2016) 65:977-989.
Neilan TG et al.
Late gadolinium enhancement among survivors of sudden cardiac arrest.
JACC Cardiovasc Imaging (2015) 8:414-423.
Grant TR000901 Grant TR000923
Huan T et al.
Genome-wide identification of microRNA expression Quantitative Trait Loci.
Nat Commun (2015) 6:6601.
Grant TR000901 Grant TR000921 Grant HL126495
A snapshot of genetic and epigenetic basis of arrhythmia and heart failure.
Front Genet (2015) 6:74.
Review Therapeutics Grant TR000931 Grant TR000901
Wei X, Liu X & Rosenzweig A.
What do we know about the cardiac benefits of exercise?
Trends Cardiovasc Med (2015) 25:529-36.
Dotson AL et al.
Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke.
J Neuroimmunol (2015) 278:289-98.
Danielson KM & Das S.
Extracellular vesicles in heart disease: Excitement for the future?
Exosomes Microvesicles (2014) 2:1.
Review exRNA and EV Biology EV Biology Grant TR000901 Grant TR000943
