The Extracellular RNA Communication Consortium has published 800+ research articles since its inception in 2013. They are listed here in reverse chronological order. Each article is tagged by category; you can browse different categories using the drop-down menu at the top of the page or by clicking on the tags of multi-category articles.
Petrosyan V et al.
Immunologically "cold" triple negative breast cancers engraft at a higher rate in patient derived xenografts.
NPJ Breast Cancer (2022) 8:104.
Spanos M et al.
Elevation of neural injury markers in patients with neurologic sequelae after hospitalization for SARS-CoV-2 infection.
iScience (2022) 25:104833.
Rufo J et al.
A sound approach to advancing healthcare systems: the future of biomedical acoustics.
Nat Commun (2022) 13:3459.
Welsh JA et al.
MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays.
Cell Rep Methods (2022) 2:100136.
Chen B et al.
Targeting non-coding RNAs to overcome cancer therapy resistance.
Signal Transduct Target Ther (2022) 7:121.
Yang S et al.
Harmonic acoustics for dynamic and selective particle manipulation.
Nat Mater (2022) 21:540-546.
Alsop E et al.
A novel tissue atlas and online tool for the interrogation of small RNA expression in human tissues and biofluids.
Front Cell Dev Biol (2022) 10:804164.
Liu H et al.
Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression.
Mol Cancer (2022) 21:74.
Alexander RP et al.
Open problems in extracellular RNA data analysis: Insights from an ERCC online workshop.
Front Genet (2021) 12:778416.
Abner JJ et al.
Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m(6)A consensus sequences.
Heliyon (2021) 7:e08519.
Zhang Q et al.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
Nat Cell Biol (2021) 23:1240-1254.
Wang Z et al.
Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes.
Microsyst Nanoeng (2021) 7:20.
Verweij FJ et al.
The power of imaging to understand extracellular vesicle biology in vivo.
Nat Methods (2021) 18:1013-1026.
Pusic KM, Kraig RP & Pusic AD.
IFNgamma-stimulated dendritic cell extracellular vesicles can be nasally administered to the brain and enter oligodendrocytes.
PLoS ONE (2021) 16:e0255778.
Bouchareychas L et al.
High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis.
iScience (2021) 24:102847.
Zheng JJ et al.
Isolation of HDL by sequential flotation ultracentrifugation followed by size exclusion chromatography reveals size-based enrichment of HDL-associated proteins.
Sci Rep (2021) 11:16086.
Pusic KM et al.
Environmental enrichment and its benefits for migraine: Dendritic cell extracellular vesicles as an effective mimetic.
J Cell Immunol (2021) 3:215-225.
Park J et al.
An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma.
Nat Biomed Eng (2021) 5:678-689.
Zhang P et al.
Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials.
Nat Commun (2021) 12:3844.
Winkle M et al.
Noncoding RNA therapeutics - challenges and potential solutions.
Nat Rev Drug Discov (2021) 20:629-651.
Muthukumar T et al.
Serum microRNA transcriptomics and acute rejection or recurrent Hepatitis C virus in human liver allograft recipients: a pilot study.
Transplantation (2022) 106:806-820.
Arab T et al.
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms.
J Extracell Vesicles (2021) 10:e12079.
Zhang J et al.
Immunomagnetic sequential ultrafiltration (iSUF) platform for enrichment and purification of extracellular vesicles from biofluids.
Sci Rep (2021) 11:8034.
Kunert-Graf JM, Sakhanenko NA & Galas DJ.
Optimized permutation testing for information theoretic measures of multi-gene interactions.
BMC Bioinformatics (2021) 22:180.
Gruner HN & McManus MT.
Examining the evidence for extracellular RNA function in mammals.
Nat Rev Genet (2021) 22:448-458.
Tosar JP et al.
RI-SEC-seq: Comprehensive profiling of nonvesicular extracellular RNAs with different stabilities.
Bio Protoc (2021) 11:e3918.
Nguyen VVT et al.
Functional assays to assess the therapeutic potential of extracellular vesicles.
J Extracell Vesicles (2020) 10:e12033.
Noren Hooten N et al.
Hitting the bullseye: Are extracellular vesicles on target?
J Extracell Vesicles (2020) 10:e12032.
Li J et al.
Angiotensin II-induced muscle atrophy via PPARgamma suppression is mediated by miR-29b.
Mol Ther Nucleic Acids (2021) 23:743-756.
Gorur A et al.
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer.
Mol Ther Nucleic Acids (2021) 23:930-943.
Chen C et al.
Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae.
Nat Commun (2021) 12:1118.
Thistlethwaite LR et al.
CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models.
PLoS Comput Biol (2021) 17:e1008550.
Crouser ED et al.
Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia.
PLoS ONE (2021) 16:e0246083.
Xie Y et al.
Microfluidic isolation and enrichment of nanoparticles.
ACS Nano (2020) 14:16220–16240.
Welsh JA et al.
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration.
J Extracell Vesicles (2020) 9:1816641.
Kaczor-Urbanowicz KE et al.
Reviews on current liquid biopsy for detection and management of pancreatic cancers.
Pancreas (2020) 49:1141-1152.
Xiao Y et al.
How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger.
J Extracell Vesicles (2020) 9:1793515.
Huang Y et al.
Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles.
J Extracell Vesicles (2020) 9:1785746.
Vaze A et al.
Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study.
PLoS ONE (2020) 15:e0236960.
Lurie E et al.
Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin.
Oncogenesis (2020) 9:62.
Zhang P et al.
Acoustic streaming vortices enable contactless, digital control of droplets.
Sci Adv (2020) 6:eaba0606.
Abels ER et al.
GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma.
Sci Rep (2020) 10:9898.
O'Brien K et al.
RNA delivery by extracellular vesicles in mammalian cells and its applications.
Nat Rev Mol Cell Biol (2020) 21:585-606.
Sung BH et al.
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells.
Nat Commun (2020) 11:2092.
Maas SLN et al.
Glioblastoma hijacks microglial gene expression to support tumor growth.
J Neuroinflammation (2020) 17:120.
Welsh JA et al.
MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments.
J Extracell Vesicles (2020) 9:1713526.
Amit M et al.
Loss of p53 drives neuron reprogramming in head and neck cancer.
Nature (2020) 578:449-454.
Perez PS et al.
Extracellular vesicles and chronic inflammation during HIV infection.
J Extracell Vesicles (2019) 8:1687275.
Xiong C et al.
Targeting forward and reverse EphB4/EFNB2 signaling by a peptide with dual functions.
Sci Rep (2020) 10:520.
Rima XY et al.
Surface engineering within a microchannel for hydrodynamic and self-assembled cell patterning.
Biomicrofluidics (2020) 14:014104.
Yang Z et al.
Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation.
Nat Biomed Eng (2020) 4:69-83.
Kalra H et al.
Extracellular vesicles containing oncogenic mutant beta-catenin activate Wnt signalling pathway in the recipient cells.
J Extracell Vesicles (2019) 8:1690217.
Russell AE et al.
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop.
J Extracell Vesicles (2019) 8:1684862.
Zaborowski MP et al.
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.
Sci Rep (2019) 9:17387.
Sun L et al.
miR-302a inhibits metastasis and cetuximab resistance in colorectal cancer by targeting NFIB and CD44.
Theranostics (2019) 9:8409-8425.
Gupta MP et al.
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.
Nat Methods (2019) 16:1269-1273.
Bei Y et al.
Correction to: Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury.
Basic Res Cardiol (2019) 114:44.
Yoneshiro T et al.
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.
Nature (2019) 572:614-619.
Batki J et al.
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat Struct Mol Biol (2019) 26:720-731.
Chen X et al.
Identifying and targeting angiogenesis-related microRNAs in ovarian cancer.
Oncogene (2019) 38:6095-6108.
Morales-Kastresana A et al.
High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.
J Extracell Vesicles (2019) 8:1597603.
Petrescu GED et al.
MicroRNA based theranostics for brain cancer: Basic principles.
J Exp Clin Cancer Res (2019) 38:231.
Lee MY et al.
A biological function based biomarker panel optimization process.
Sci Rep (2019) 9:7365.
Watts JK, Brown RH & Khvorova A.
Nucleic acid therapeutics for neurological diseases.
Neurotherapeutics (2019) 16:245-247.
Koupenova M et al.
The role of platelets in mediating a response to human influenza infection.
Nat Commun (2019) 10:1780.
Duong P et al.
Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles.
PLoS One (2019) 14:e0215324.
Mazzu YZ et al.
miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFbeta, and Wnt signaling.
Sci Rep (2019) 9:3197.
Grani C et al.
Comparison of myocardial fibrosis quantification methods by cardiovascular magnetic resonance imaging for risk stratification of patients with suspected myocarditis.
J Cardiovasc Magn Reson (2019) 21:14.
Belair CD et al.
High-throughput, efficient, and unbiased capture of small RNAs from low-input samples for sequencing.
Sci Rep (2019) 9:2262.
Bei Y et al.
Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury.
BMC Med (2019) 17:42.
Carrero I et al.
Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments.
Oncogene (2019) 38:3551-3568.
Krichevsky AM & Uhlmann EJ.
Oligonucleotide therapeutics as a new class of drugs for malignant brain tumors: Targeting mRNAs, regulatory RNAs, mutations, combinations, and beyond.
Neurotherapeutics (2019) 16:319-347.
Varkaris A et al.
Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer.
Br J Cancer (2019) 120:340-345.
Thery C, Witwer KW, et al.
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
J Extracell Vesicles (2018) 7:1535750.
Cortez MA et al.
Role of miRNAs in immune responses and immunotherapy in cancer.
Genes Chromosomes Cancer (2019) 58:244-253.
Chen B et al.
Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag.
Nat Commun (2018) 9:5065.
Shah R, Patel T & Freedman JE.
Circulating extracellular vesicles in human disease.
N Engl J Med (2018) 379:2180-2181.
Zhou S et al.
Chronic Platelet-derived Growth Factor Receptor signaling exerts control over initiation of protein translation in glioma.
Life Sci Alliance (2018) 1:e201800029.
Lusardi TA et al.
Analytics of Cerebrospinal Fluid microRNA quantitative PCR studies.
Mol Neurobiol (2019) 56:4988-4999.
Wang QL et al.
Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways.
Theranostics (2018) 8:4912-4924.
Suryawanshi H et al.
A single-cell survey of the human first-trimester placenta and decidua.
Sci Adv (2018) 4:eaau4788.
Gustafsson G et al.
Secretion and uptake of alpha-synuclein via extracellular vesicles in cultured cells.
Cell Mol Neurobiol (2018) 38:1539-1550.
Antoury L et al.
Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of Muscular Dystrophies.
Nat Commun (2018) 9:3906.
Regev K et al.
Identification of MS-specific serum miRNAs in an international multicenter study.
Neurol Neuroimmunol Neuroinflamm (2018) 5:e491.
Monroig-Bosque PDC et al.
OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.
Sci Rep (2018) 8:13106.
Jun HJ et al.
A PDGFRalpha-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Nat Commun (2018) 9:3116.
Gharpure KM et al.
FABP4 as a key determinant of metastatic potential of ovarian cancer.
Nat Commun (2018) 9:2923.
Broekman ML et al.
Multidimensional communication in the microenvirons of glioblastoma.
Nat Rev Neurol (2018) 14:482-495.
Umamaheswaran S et al.
Stress, inflammation, and eicosanoids: an emerging perspective.
Cancer Metastasis Rev (2018) 37:203-211.
Badawi M et al.
CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128.
Oncotarget (2018) 9:26032-26045.
Ghai V et al.
Genome-wide profiling of urinary extracellular vesicle microRNAs associated with diabetic nephropathy in type 1 diabetes.
Kidney Int Rep (2018) 3:555-572.
George J, Yan IK & Patel T.
Nanovesicle-mediated delivery of anticancer agents effectively induced cell death and regressed intrahepatic tumors in athymic mice.
Lab Invest (2018) 98:895-910.
Koupenova M et al.
Micro RNAs from DNA viruses are found widely in plasma in a large observational human population.
Sci Rep (2018) 8:6397.
Ricklefs FL et al.
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.
Sci Adv (2018) 4:eaar2766.
Roy S, Hochberg FH & Jones PS.
Extracellular vesicles: the growth as diagnostics and therapeutics; a survey.
J Extracell Vesicles (2018) 7:1438720.
Koupenova M et al.
Circulating platelets as mediators of immunity, inflammation, and thrombosis.
Circ Res (2018) 122:337-351.
Hulsmans M et al.
Cardiac macrophages promote diastolic dysfunction.
J Exp Med (2018) 215:423-440.
Chen X et al.
RNA interference-based therapy and its delivery systems.
Cancer Metastasis Rev (2018) 37:107-124.
Foye C et al.
Comparison of miRNA quantitation by Nanostring in serum and plasma samples.
PLoS ONE (2017) 12:e0189165.
Vannini I et al.
Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.
Nat Commun (2017) 8:1801.
Bei Y et al.
Extracellular vesicles in cardiovascular theranostics.
Theranostics (2017) 7:4168-4182.
Mitamura T et al.
Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).
Oncogene (2018) 37:722-731.
Shen P et al.
To Wnt or lose: The missing non-coding linc in colorectal cancer.
Int J Mol Sci (2017) 18:9.
Datta A et al.
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
Cancer Lett (2017) 408:73-81.
Vasilescu C et al.
Circulating miRNAs in sepsis-A network under attack: An in-silico prediction of the potential existence of miRNA sponges in sepsis.
PLoS ONE (2017) 12:e0183334.
Zhu X et al.
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.
J Extracell Vesicles (2017) 6:1324730.
Pathan M et al.
A novel community driven software for functional enrichment analysis of extracellular vesicles data.
J Extracell Vesicles (2017) 6:1321455.
Sutaria DS et al.
Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery.
J Extracell Vesicles (2017) 6:1333882.
Rigoutsos I et al.
N-BLR, a primate-specific non-coding transcript, leads to colorectal cancer invasion and migration.
Genome Biol (2017) 18:98.
Klingenberg M et al.
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.
J Hepatol (2017) 67:603-618.
Clancy L et al.
The role of RNA uptake in platelet heterogeneity.
Thromb Haemost (2017) 117:948-961.
Giza DE et al.
Cellular and viral microRNAs in sepsis: Mechanisms of action and clinical applications.
Cell Death Differ (2016) 23:1906-1918.
Ghai V & Wang K.
Recent progress toward the use of circulating microRNAs as clinical biomarkers.
Arch Toxicol (2016) 90:2959-2978.
Ciccone M & Calin GA.
MicroRNAs in chronic lymphocytic leukemia: An old disease with new genetic insights.
MicroRNA (2016) 5:106-112.
Parasramka MA et al.
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma.
Pharmacol Ther (2016) 161:67-78.
Byron SA et al.
Translating RNA sequencing into clinical diagnostics: Opportunities and challenges.
Nat Rev Genet (2016) 17:257-71. Related blog post
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers.
Eur Urol (2016) 70:312-22.
Rupaimoole R et al.
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Oncogene (2016) 35:4312-20. Related blog post
Shields BB et al.
A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.
Mol Syst Biol (2015) 11:842.
Zhang S et al.
CDK5 regulates paclitaxel sensitivity in ovarian cancer cells by modulating AKT activation, p21Cip1- and p27Kip1-mediated G1 cell cycle arrest and apoptosis.
PLoS ONE (2015) 10:e0131833.
Camussi G & Quesenberry PJ.
Perspectives on the potential therapeutic uses of vesicles.
Exosomes Microvesicles (2013) 1:6.
Wong HK et al.
The Cancer Genome Atlas analysis predicts microRNA for targeting cancer growth and vascularization in glioblastoma.
Mol Ther (2015) 23:1234-47.
Li K et al.
Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-kappaB-driven inflammation and atherosclerosis.
Circ Res (2015) 117:e1-e11.
Miyake TM et al.
XPO1/CRM1 inhibition causes antitumor effects by mitochondrial accumulation of eIF5A.
Clin Cancer Res (2015) 21:3286-97.
Liu X et al.
miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.
Cell Metab (2015) 21:584-95.
Gonzalez-Villasana V et al.
Rac1/Pak1/p38/MMP-2 axis regulates angiogenesis in ovarian cancer.
Clin Cancer Res (2015) 21:2127-37.
Danielson KM & Das S.
Extracellular vesicles in heart disease: Excitement for the future?
Exosomes Microvesicles (2014) 2:1.
van den Beucken T et al.
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.
Nat Commun (2014) 5:5203.
Gangoda L et al.
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
Proteomics (2015) 15:260-71.
Leung CS et al.
Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
Nat Commun (2014) 5:5092.
Han C et al.
The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression.
Cell Rep (2014) 8:1447-60.
Krzeszinski JY et al.
MiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.
Nature (2014) 512:431-5.
Thomas MF, L'Etoile ND & Ansel KM.
Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.
Trends Genet (2014) 30:298-307.
Yang L et al.
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer.
Mol Syst Biol (2014) 10:728.
Hu W et al.
Notch3 pathway alterations in ovarian cancer.
Cancer Res (2014) 74:3282-93.
Takahashi K et al.
Long noncoding RNA in liver diseases.
Hepatology (2014) 60:744-53.
Beaulieu LM et al.
Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans.
Arterioscler Thromb Vasc Biol (2014) 34:552-64.
Ozpolat B, Sood AK & Lopez-Berestein G.
Liposomal siRNA nanocarriers for cancer therapy.
Adv Drug Deliv Rev (2014) 66:110-6.