Resources and Technology

Huang T et al.

Acoustofluidic scanning fluorescence nanoscopy with large field of view.

Res Sq AOP 2023-06-26.

Saftics A et al.

Single Extracellular VEsicle Nanoscopy.

J Extracell Vesicles (2023) 12:e12346.

Andronico LA et al.

Improving multicolor colocalization in single-vesicle flow cytometry with vesicle transit time.

Anal Chem (2023) 95:10492-10497.

Fordjour FK et al.

Exomap1 mouse: a transgenic model for in vivo studies of exosome biology.

bioRxiv AOP 2023-05-29.

Arce JE et al.

The NanoFlow Repository.

Bioinformatics (2023) 39.

LaPlante EL et al.

exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers.

Cell Genom (2023) 3:100303.

Zhang Y et al.

Chiral graphene quantum dots enhanced drug loading into small extracellular vesicles.

ACS Nano (2023) 17:10191-10205.

Sharma H et al.

A Scalable high-throughput isoelectric fractionation platform for extracellular nanocarriers: Comprehensive and bias-free isolation of ribonucleoproteins from plasma, urine, and saliva.

ACS Nano (2023) 17:9388-9404.

Welsh JA et al.

A compendium of single extracellular vesicle flow cytometry.

J Extracell Vesicles (2023) 12:e12299.

Kumar S et al.

Quantifying PON1 on HDL with nanoparticle-gated electrokinetic membrane sensor for accurate cardiovascular risk assessment.

Nat Commun (2023) 14:557.

Chen L et al.

A home-made pipette droplet microfluidics rapid prototyping and training kit for digital PCR, microorganism/cell encapsulation and controlled microgel synthesis.

Sci Rep (2023) 13:184.

McCarthy KP et al.

An integrated ion-exchange membrane-based microfluidic device for irreversible dissociation and quantification of miRNA from ribonucleoproteins.

Lab Chip (2023) 23:285-294.

Zhang C et al.

Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins.

Commun Biol (2022) 5:1358.

Kaczor-Urbanowicz KE & Wong DTW.

RNA sequencing analysis of saliva exRNA.

Methods Mol Biol (2023) 2588:3-11.

Zhang J et al.

A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER).

Sci Adv (2022) 8:eade0640.

Banman A et al.

ApoE modifier alleles for Alzheimer’s disease discovered by information theory dependency measures: MIST software package.

J Comput Biol (2023) 30:323-336.

Nguyen LTH et al.

An immunogold single extracellular vesicular RNA and protein ((Au) SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients.

J Extracell Vesicles (2022) 11:e12258.

Mateescu B et al.

Phase 2 of Extracellular RNA Communication Consortium charts next-generation approaches for extracellular RNA research.

iScience (2022) 25:104653.

Arifin DR, Witwer KW & Bulte JWM.

Non-invasive imaging of extracellular vesicles: Quo vaditis in vivo?

J Extracell Vesicles (2022) 11:e12241.

Rufo J et al.

A sound approach to advancing healthcare systems: the future of biomedical acoustics.

Nat Commun (2022) 13:3459.

Jin G et al.

Intelligent nanoscope for rapid nanomaterial identification and classification.

Lab Chip (2022) 22:2978-2985.

Rima XY et al.

Microfluidic harvesting of breast cancer tumor spheroid-derived extracellular vesicles from immobilized microgels for single-vesicle analysis.

Lab Chip (2022) 22:2502-2518.

Wang Z et al.

Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation.

Microsyst Nanoeng (2022) 8:45.

Gomes DE & Witwer KW.

L1CAM-associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization.

J Extracell Biol (2022) 1.

Welsh JA et al.

MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays.

Cell Rep Methods (2022) 2:100136.

Yang S et al.

Harmonic acoustics for dynamic and selective particle manipulation.

Nat Mater (2022) 21:540-546.

Alsop E et al.

A novel tissue atlas and online tool for the interrogation of small RNA expression in human tissues and biofluids.

Front Cell Dev Biol (2022) 10:804164.

Zhao Z et al.

Ring-shaped photoacoustic tweezers for single particle manipulation.

Opt Lett (2022) 47:826-829.

Wakefield DL et al.

Molecular imaging of HER2 in patient tissues with touch prep-Quantitative Single Molecule Localization Microscopy.

Methods Mol Biol (2022) 2394:231-248.

Chu SK et al.

Comprehensive evaluation of noise reduction methods for single-cell RNA sequencing data.

Brief Bioinform (2022) 23.

Alexander RP et al.

Open problems in extracellular RNA data analysis: Insights from an ERCC online workshop.

Front Genet (2021) 12:778416.

Witwer KW et al.

Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles.

J Extracell Vesicles (2021) 10:e12182.

Hao N et al.

Acoustofluidic multimodal diagnostic system for Alzheimer’s disease.

Biosens Bioelectron (2022) 196:113730.

Bittel M et al.

Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo.

J Extracell Vesicles (2021) 10:e12159.

Valkov N et al.

snRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.

Life Sci Alliance (2021) 4.

Zhong R et al.

Acoustofluidic droplet sorter based on single phase focused transducers.

Small (2021) 17:e2103848.

Zhang Y et al.

Nanoparticle-assisted detection of nucleic acids in a polymeric nanopore with a large pore size.

Biosens Bioelectron (2022) 196:113697.

van der Pol E, Welsh JA & Nieuwland R.

Minimum information to report about a flow cytometry experiment on extracellular vesicles: Communication from the ISTH SSC subcommittee on vascular biology.

J Thromb Haemost (2022) 20:245-251.

Wang Z et al.

Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes.

Microsyst Nanoeng (2021) 7:20.

Verweij FJ et al.

The power of imaging to understand extracellular vesicle biology in vivo.

Nat Methods (2021) 18:1013-1026.

Li J et al.

Acoustic tweezer with complex boundary-free trapping and transport channel controlled by shadow waveguides.

Sci Adv (2021) 7:eabi5502.

Park J et al.

An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma.

Nat Biomed Eng (2021) 5:678-689.

Giraldez MD & Tewari M.

Phospho-RNAseq profiling of extracellular mRNAs and lncRNAs.

Methods Mol Biol (2021) 2348:257-271.

Zhang P et al.

Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials.

Nat Commun (2021) 12:3844.

Oliveira-Jr GP et al.

Electrophoretic mobility shift as a molecular beacon-based readout for miRNA detection.

Biosens Bioelectron (2021) 189:113307.

Thompson L et al.

Quantification of cellular densities and antigenic properties using magnetic levitation.

J Vis Exp AOP 2021-05-17.

Guo C et al.

Choice of selectable marker affects recombinant protein expression in cells and exosomes.

J Biol Chem (2021) 297:100838.

Zhao S et al.

Fabrication of tunable, high-molecular-weight polymeric nanoparticles via ultrafast acoustofluidic micromixing.

Lab Chip (2021) 21:2453-2463.

Arab T et al.

Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms.

J Extracell Vesicles (2021) 10:e12079.

Zhang J et al.

Immunomagnetic sequential ultrafiltration (iSUF) platform for enrichment and purification of extracellular vesicles from biofluids.

Sci Rep (2021) 11:8034.

Kunert-Graf JM, Sakhanenko NA & Galas DJ.

Optimized permutation testing for information theoretic measures of multi-gene interactions.

BMC Bioinformatics (2021) 22:180.

Jiang Y et al.

High-throughput counting and superresolution mapping of tetraspanins on exosomes using a single-molecule sensitive flow technique and transistor-like semiconducting polymer dots.

Angew Chem Int Ed Engl (2021) 60:13470-13475.

Andronico LA et al.

Sizing extracellular vesicles using membrane dyes and a single molecule-sensitive flow analyzer.

Anal Chem (2021) 93:5897-5905.

Tosar JP et al.

RI-SEC-seq: Comprehensive profiling of nonvesicular extracellular RNAs with different stabilities.

Bio Protoc (2021) 11:e3918.

Martin-Jaular L et al.

Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection.

EMBO J (2021) 40:e105492.

Welsh JA et al.

A simple, high-throughput method of protein and label removal from extracellular vesicle samples.

Nanoscale (2021) 13:3737-3745.

Zhu H et al.

Acoustohydrodynamic tweezers via spatial arrangement of streaming vortices.

Sci Adv (2021) 7:eabc7885.

Gu Y et al.

Acoustofluidic centrifuge for nanoparticle enrichment and separation.

Sci Adv (2021) 7.

Thistlethwaite LR et al.

CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models.

PLoS Comput Biol (2021) 17:e1008550.

Morales-Kastresana A, Welsh JA & Jones JC.

Detection and sorting of extracellular vesicles and viruses using nanoFACS.

Curr Protoc Cytom (2020) 95:e81.

Xie Y et al.

Microfluidic isolation and enrichment of nanoparticles.

ACS Nano (2020) 14:16220–16240.

Burnie J et al.

Flow virometry quantification of host proteins on the surface of HIV-1 pseudovirus particles.

Viruses (2020) 12:1296.

Hao N et al.

Acoustofluidics-assisted fluorescence-SERS bimodal biosensors.

Small (2020) 16:e2005179.

Zhang P et al.

Deterministic droplet coding via acoustofluidics.

Lab Chip (2020) 20:4466-4473.

Welsh JA et al.

Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration.

J Extracell Vesicles (2020) 9:1816641.

Kaczor-Urbanowicz KE et al.

Reviews on current liquid biopsy for detection and management of pancreatic cancers.

Pancreas (2020) 49:1141-1152.

Huang Y et al.

Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles.

J Extracell Vesicles (2020) 9:1785746.

Welsh JA & Jones JC.

Small particle fluorescence and light scatter calibration using FCMPASS software.

Curr Protoc Cytom (2020) 94:e79.

Tian Z et al.

Generating multifunctional acoustic tweezers in Petri dishes for contactless, precise manipulation of bioparticles.

Sci Adv (2020) 6:eabb0494.

Royo F et al.

Methods for separation and characterization of extracellular vesicles: Results of a worldwide survey performed by the ISEV Rigor and Standardization subcommittee.

Cells (2020) 9:1955.

Suea-Ngam A et al.

Enzyme-assisted nucleic acid detection for infectious disease diagnostics: Moving toward the point-of-care.

ACS Sens (2020) 5:2701-2723.

Zhong Z et al.

Hardware design and fault-tolerant synthesis for digital acoustofluidic biochips.

IEEE Trans Biomed Circuits Syst (2020) 14:1065-1078.

Liu P et al.

Acoustofluidic multi-well plates for enrichment of micro/nano particles and cells.

Lab Chip (2020) 20:3399-3409.

Lurie E et al.

Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin.

Oncogenesis (2020) 9:62.

Zhang P et al.

Acoustic streaming vortices enable contactless, digital control of droplets.

Sci Adv (2020) 6:eaba0606.

Gu Y et al.

Acoustofluidic holography for micro- to nanoscale particle manipulation.

ACS Nano (2020) 14:14635-14645.

Jin G et al.

Acoustofluidic scanning nanoscope with high resolution and large field of view.

ACS Nano (2020) 14:8624-8633.

Abels ER et al.

GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma.

Sci Rep (2020) 10:9898.

Zhang P et al.

Acoustic microfluidics.

Annu Rev Anal Chem (Palo Alto Calif) (2020) 13:17-43.

Sung BH et al.

A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells.

Nat Commun (2020) 11:2092.

Hao N et al.

Acoustofluidics-assisted engineering of multifunctional three-dimensional zinc oxide nanoarrays.

ACS Nano (2020) 14:6150-6163.

Maas SLN et al.

Glioblastoma hijacks microglial gene expression to support tumor growth.

J Neuroinflammation (2020) 17:120.

Hunter-Zinck H et al.

Genotyping array design and data quality control in the Million Veteran Program.

Am J Hum Genet (2020) 106:535-548.

Zhao S et al.

A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers.

Lab Chip (2020) 20:1298-1308.

Wang C, Senapati S & Chang HC.

Liquid biopsy technologies based on membrane microfluidics: High-yield purification and selective quantification of biomarkers in nanocarriers.

Electrophoresis (2020) 41:1878-1892.

Bachman H et al.

Low-frequency flexural wave based microparticle manipulation.

Lab Chip (2020) 20:1281-1289.

Welsh JA et al.

MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments.

J Extracell Vesicles (2020) 9:1713526.

Bachman H et al.

An acoustofluidic device for efficient mixing over a wide range of flow rates.

Lab Chip (2020) 20:1238-1248.

Wei S et al.

A rapid and simple bead-bashing-based method for genomic DNA extraction from mammalian tissue.

Biotechniques (2020) 68:240-244.

Xie Y et al.

Acoustic cell separation based on biophysical properties.

J Biomech Eng (2020) 142:0310051-9.

Oliveira GP Jr et al.

Detection of extracellular vesicle RNA using molecular beacons.

iScience (2020) 23:100782.

Rima XY et al.

Surface engineering within a microchannel for hydrodynamic and self-assembled cell patterning.

Biomicrofluidics (2020) 14:014104.

Godoy PM et al.

Comparison of reproducibility, accuracy, sensitivity, and specificity of miRNA quantification platforms.

Cell Rep (2019) 29:4212-4222.e5.

Yang Z et al.

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation.

Nat Biomed Eng (2020) 4:69-83.

Zaborowski MP et al.

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.

Sci Rep (2019) 9:17387.

Gupta MP et al.

Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.

Nat Methods (2019) 16:1269-1273.

Ishiguro K, Yan IK & Patel T.

Isolation of tissue extracellular vesicles from the liver.

J Vis Exp (2019) 150:e58649.

Morales-Kastresana A et al.

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.

J Extracell Vesicles (2019) 8:1597603.

Gyuris A et al.

Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity.

Cell Rep (2019) 27:3972-3987.e6.

Wei Z et al.

Co-cultures of glioma stem cells and primary neurons, astrocytes, microglia, and endothelial cells for investigation of intercellular communication in the brain.

Front Neurosci (2019) 13:361.

Giraldez MD et al.

Phospho-RNA-seq: a modified small RNA-seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma.

EMBO J (2019) 38:e101695.

Akat KM et al.

Detection of circulating extracellular mRNAs by modified small-RNA-sequencing analysis.

JCI Insight (2019) 5:9.

Duong P et al.

Cushioned-Density Gradient Ultracentrifugation (C-DGUC) improves the isolation efficiency of extracellular vesicles.

PLoS One (2019) 14:e0215324.

Zhang Q et al.

Transfer of functional cargo in exomeres.

Cell Rep (2019) 27:940-954.e6.

Rozowsky J et al.

exceRpt: A comprehensive analytic platform for extracellular RNA profiling.

Cell Syst (2019) 8:352-357.e3.

Srinivasan S et al.

Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation.

Cell (2019) 177:446-462.e16.

Murillo OD et al.

exRNA Atlas analysis reveals distinct extracellular RNA Cargo types and their carriers present across human biofluids.

Cell (2019) 177:463-477.e15.

Zaborowski MP et al.

Methods for systematic identification of membrane proteins for specific capture of cancer-derived extracellular vesicles.

Cell Rep (2019) 27:255-268.e6.

Belair CD et al.

High-throughput, efficient, and unbiased capture of small RNAs from low-input samples for sequencing.

Sci Rep (2019) 9:2262.

Thery C, Witwer KW, et al.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

J Extracell Vesicles (2018) 7:1535750.

Yu H et al.

beRBP: binding estimation for human RNA-binding proteins.

Nucleic Acids Res (2019) 47:e26.

Godoy PM et al.

Large differences in small RNA composition between human biofluids.

Cell Rep (2018) 25:1346-1358.

Haraszti RA et al.

Exosomes produced from 3D Cultures of MSCs by Tangential Flow Filtration show higher yield and improved activity.

Mol Ther (2018) 26:2838-2847.

Wei F et al.

Electric field-induced release and measurement liquid biopsy for noninvasive early lung cancer assessment.

J Mol Diagn (2018) 20:738-742.

Giraldez MD et al.

Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.

Nat Biotechnol (2018) 36:746-757.

Dluzen DF et al.

Extracellular RNA profiles with human age.

Aging Cell (2018) 17:e12785.

Max KEA et al.

Human plasma and serum extracellular small RNA reference profiles and their clinical utility.

Proc Natl Acad Sci USA (2018) 115 :E5334-E5343.

Heintz-Buschart A et al.

Small RNA profiling of low biomass samples: Identification and removal of contaminants.

BMC Biol (2018) 16:52.

Yeri A et al.

Evaluation of commercially available small RNASeq library preparation kits using low input RNA.

BMC Genomics (2018) 19:331.

Vujic A et al.

Exercise induces new cardiomyocyte generation in the adult mammalian heart.

Nat Commun (2018) 9:1659.

Li F et al.

Characterization of human salivary extracellular RNA by next-generation sequencing.

Clin Chem (2018) 64:1085-1095.

Yan IK, Lohray R & Patel T.

Droplet digital PCR for quantitation of extracellular RNA.

Methods Mol Biol (2018) 1740:155-162.

Matsuda A & Patel T.

Milk-derived extracellular vesicles for therapeutic delivery of small interfering RNAs.

Methods Mol Biol (2018) 1740:187-197.

Yan IK, Berdah VX & Patel T.

Isolation of extracellular RNA from bile.

Methods Mol Biol (2018) 1740:59-67.

Li K et al.

Isolation of plasma lipoproteins as a source of extracellular RNA.

Methods Mol Biol (2018) 1740:139-153.

Shukla N, Yan IK & Patel T.

Multiplexed detection and quantitation of extracellular vesicle RNA expression using NanoString.

Methods Mol Biol (2018) 1740:177-185.

Filant J et al.

Isolation of extracellular RNA from serum/plasma.

Methods Mol Biol (2018) 1740:43-57.

Didiot MC et al.

Loading of extracellular vesicles with hydrophobically modified siRNAs.

Methods Mol Biol (2018) 1740:199-214.

Li K et al.

Cushioned-Density Gradient Ultracentrifugation (C-DGUC): A refined and high performance method for the isolation, characterization, and use of exosomes.

Methods Mol Biol (2018) 1740:69-83.

Etheridge A et al.

Preparation of small RNA NGS libraries from biofluids.

Methods Mol Biol (2018) 1740:163-175.

Shao H et al.

New technologies for analysis of extracellular vesicles.

Chem Rev (2018) 118:1917-1950.

Foye C et al.

Comparison of miRNA quantitation by Nanostring in serum and plasma samples.

PLoS ONE (2017) 12:e0189165.

Slenter DN et al.

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research.

Nucleic Acids Res (2018) 46:D661-D667.

Amorim MG et al.

A total transcriptome profiling method for plasma-derived extracellular vesicles: Applications for liquid biopsies.

Sci Rep (2017) 7:14395.

Wei Z et al.

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells.

Nat Commun (2017) 8:1145.

Nolan JP & Duggan E.

Analysis of individual extracellular vesicles by flow cytometry.

Methods Mol Biol (2018) 1678:79-92.

Wu X et al.

sRNAnalyzer: a flexible and customizable small RNA sequencing data analysis pipeline.

Nucleic Acids Res (2017) 45:12140-12151.

Kaczor-Urbanowicz KE et al.

Novel approaches for bioinformatic analysis of salivary RNA sequencing data for development.

Bioinformatics (2018) 34:1-8.

Wu AY & Lai CP.

Tracking extracellular vesicles delivery and RNA translation using multiplexed reporters.

Methods Mol Biol (2017) 1660:255-265.

Gogakos T et al.

Characterizing expression and processing of precursor and mature human tRNAs by hydro-tRNAseq and PAR-CLIP.

Cell Rep (2017) 20:1463-1475.

Saugstad JA et al.

Analysis of extracellular RNA in cerebrospinal fluid.

J Extracell Vesicles (2017) 6:1317577.

Pathan M et al.

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

J Extracell Vesicles (2017) 6:1321455.

Sun G et al.

Concentration-gradient stabilization with segregated counter- and co-ion paths: a quasistationary depletion front for robust molecular isolation or concentration.

Phys Rev Appl (2017) 7.

Jayaram H et al.

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: a pilot study.

Invest Ophthalmol Vis Sci (2017) 58:2884-2890.

Mateescu B et al.

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper.

J Extracell Vesicles (2017) 6:1286095.

Yeri A et al.

Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects.

Sci Rep (2017) 7:44061.

Nolan JP & Jones JC.

Detection of platelet vesicles by flow cytometry.

Platelets (2017) 28:256-262.

Grossman RL et al.

Collaborating to compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.

Clin Pharmacol Ther (2017) 101:589-592.

Ong WQ et al.

Live cell imaging of endogenous mRNA using RNA-based fluorescence “Turn-On” probe.

ACS Chem Biol (2017) 12:200-205.

Danielson KM et al.

High throughput sequencing of extracellular RNA from human plasma.

PLoS ONE (2017) 12:e0164644.

Lee I et al.

The importance of standardization on analyzing circulating RNA.

Mol Diagn Ther (2017) 21:259-268.

Baldwin S et al.

Analyzing the miRNA content of extracellular vesicles by fluorescence nanoparticle tracking.

Nanomedicine (2017) 13:765-770.

Majem B et al.

RNA sequencing analysis of salivary extracellular RNA.

Methods Mol Biol (2017) 1537:17-36.

Haraszti RA et al.

High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.

J Extracell Vesicles (2016) 5:32570.

Wei Z et al.

Fetal bovine serum RNA interferes with the cell culture derived extracellular RNA.

Sci Rep (2016) 6:31175.

Higginbotham JN et al.

Identification and characterization of EGF receptor in individual exosomes by Fluorescence-Activated Vesicle Sorting.

J Extracell Vesicles (2016) 5:29254.

Freedman JE et al.

Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma.

Nat Commun (2016) 7:11902.

Shah R et al.

Discordant expression of circulating microRNA from cellular and extracellular sources.

PLoS ONE (2016) 11:e0153691.

Freedman JE et al.

Diverse human extracellular RNAs are widely detected in human plasma.

Nat Commun (2016) 7:11106.

Cheung KH et al.

Extending gene ontology in the context of extracellular RNA and vesicle communication.

J Biomed Semantics (2016) 7:19.

Akers JC et al.

Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid.

Cancer Biomark (2016) 17:125-32.

Tanriverdi K et al.

Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative Polymerase Chain Reaction.

Anal Biochem (2016) 501:66-74.

Zaborowski MP et al.

Extracellular vesicles: Composition, biological relevance, and methods of study.

Bioscience (2015) 65:783-797.

Xiao H et al.

Differential proteomic analysis of human saliva using Tandem Mass Tags quantification for gastric cancer detection.

Sci Rep (2016) 6:22165.

Akers JC et al.

Comparative analysis of technologies for quantifying extracellular vesicles (EVs) in clinical cerebrospinal fluids (CSF).

PLoS ONE (2016) 11:e0149866.

Yuan T et al.

Plasma extracellular RNA profiles in healthy and cancer patients.

Sci Rep (2016) 6:19413.

Ben-Dov IZ et al.

Cell and microvesicle urine microRNA deep sequencing profiles from healthy individuals: Observations with potential impact on biomarker studies.

PLoS ONE (2016) 11:e0147249.

Danielson KM et al.

Diurnal variations of circulating extracellular vesicles measured by nano flow cytometry.

PLoS ONE (2016) 11:e0144678.

Keerthikumar S et al.

ExoCarta: A web-based compendium of exosomal cargo.

J Mol Biol (2016) 428:688-692.

Schwarzenbach H et al.

Data normalization strategies for microRNA quantification.

Clin Chem (2015) 61:1333-42.

Ainsztein AM et al.

The NIH Extracellular RNA Communication Consortium.

J Extracell Vesicles (2015) 4:27493.

Laurent LC et al.

Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.

J Extracell Vesicles (2015) 4:26533.

Subramanian SL et al.

Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies.

J Extracell Vesicles (2015) 4:27497.

Li X, Mauro M & Williams Z.

Comparison of plasma extracellular RNA isolation kits reveals kit-dependent biases.

Biotechniques (2015) 59:13-7.

Lai CP et al.

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.

Nat Commun (2015) 6:7029.

Shao H et al.

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma.

Nat Commun (2015) 6:6999.

Tewari M.

A functional extracellular transcriptome in animals? Implications for biology, disease and medicine.

Genome Biol (2015) 16:47.

Chiang SH et al.

RNAPro*SAL: a device for rapid and standardized collection of saliva RNA and proteins.

Biotechniques (2015) 58:69-76.

Lotvall J et al.

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.

J Extracell Vesicles (2014) 3:26913.

Kim DK et al.

EVpedia: a community web portal for extracellular vesicles research.

Bioinformatics (2015) 31:933-9.

Bahn JH et al.

The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva.

Clin Chem (2015) 61:221-30.

Kutmon M et al.

WikiPathways app for Cytoscape: Making biological pathways amenable to network analysis and visualization.

F1000Research (2014) 3:152.

Takahashi K et al.

Analysis of extracellular RNA by digital PCR.

Front Oncol (2014) 4:129.

Grange C et al.

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging.

Int J Mol Med (2014) 33:1055-63.

Ben-Dov IZ et al.

Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: Description of miRNA profiles at baseline.

PLoS ONE (2014) 9:e86856.

Lai CP et al.

Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter.

ACS Nano (2014) 8:483-94.

Chen WW et al.

BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles.

Mol Ther Nucleic Acids (2013) 2:e109.