Grant Project Page
Morris KV & Witwer KW.
The evolving paradigm of extracellular vesicles in intercellular signaling and delivery of therapeutic RNAs.
Mol Ther (2022) 30:2393-2394.
Review Therapeutics Grant TR000943 Grant CA241694
Lu Z et al.
SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
J Clin Invest (2022) 132.
Grant TR000943 Grant CA241703
Chen B et al.
Targeting non-coding RNAs to overcome cancer therapy resistance.
Signal Transduct Target Ther (2022) 7:121.
Review exRNA Biology Therapeutics Grant TR000943
Hao N et al.
Acoustofluidic multimodal diagnostic system for Alzheimer”s disease.
Biosens Bioelectron (2022) 196:113730.
Biomarkers Resources and Technology Grant TR000943 Grant TR002978
Dragomir MP, Knutsen E & Calin GA.
Classical and noncanonical functions of miRNAs in cancers.
Trends Genet (2022) 38:379-394.
Review exRNA Biology Grant TR000943 Grant DA049098
Li J et al.
Acoustic tweezer with complex boundary-free trapping and transport channel controlled by shadow waveguides.
Sci Adv (2021) 7:eabi5502.
Resources and Technology Grant TR000943 Grant TR002978
Ma S et al.
CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance.
Cell Rep (2021) 36:109549.
exRNA and EV Biology EV Biology Biomarkers Therapeutics Grant TR000943
Mohapatra S & Calin G.
JAM-ming miR-21.
Cell Death Differ (2021) 28:2837-2839.
Review Grant TR000880 Grant TR000943
Winkle M et al.
Noncoding RNA therapeutics – challenges and potential solutions.
Nat Rev Drug Discov (2021) 20:629-651.
Review Therapeutics Grant TR000943 Grant TR000933
Gorur A et al.
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer.
Mol Ther Nucleic Acids (2021) 23:930-943.
Therapeutics Grant TR000901 Grant TR000943
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype.
Cell Rep (2021) 34:108726.
exRNA and EV Biology EV Biology Grant TR000943
Silverman DA et al.
Cancer-associated neurogenesis and nerve-cancer cross-talk.
Cancer Res (2021) 81:1431-1440.
Review exRNA and EV Biology EV Biology Grant TR000943
Anfossi S & Calin GA.
Gut microbiota: a new player in regulating immune- and chemo-therapy efficacy.
Cancer Drug Resist (2020) 3:356-370.
Vaze A et al.
Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study.
PLoS ONE (2020) 15:e0236960.
Biomarkers Grant TR000943 Grant TR000921
The long noncoding RNA CCAT2 induces chromosomal instability through BOP1 – AURKB signaling.
Gastroenterology (2020) 159:2146-2162.e33.
Grant TR000943 Grant CA241685
Drula R et al.
MicroRNAs from liquid biopsy derived extracellular vesicles: Recent advances in detection and characterization methods.
Cancers (Basel) (2020) 12:2009.
Review exRNA and EV Biology exRNA Biology EV Biology Grant TR000943
Chen F et al.
Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in Acute Myeloid Leukaemia: Therapeutic implications.
J Cell Mol Med (2020) 24:7378-7392.
Therapeutics Grant TR000943
Tran AM et al.
A new world of biomarkers and therapeutics for female reproductive system and breast cancers: Circular RNAs.
Front Cell Dev Biol (2020) 8:50.
Review Biomarkers Therapeutics Grant TR000943
Pichler M et al.
Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer.
Gut (2020) 69:1818-1831.
Oliveira GP Jr et al.
Detection of extracellular vesicle RNA using molecular beacons.
iScience (2020) 23:100782.
Resources and Technology Grant TR000943
Xiong C et al.
Targeting forward and reverse EphB4/EFNB2 signaling by a peptide with dual functions.
Sci Rep (2020) 10:520.
Grant TR000943
El-Arabey AA et al.
GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma.
Cell Signal (2020) 68:109539.
Therapeutics Grant TR000943 Grant TR002884
Parashar D et al.
miRNA551b-3p activates an oncostatin signaling module for the progression of triple-negative breast cancer.
Cell Rep (2019) 29:4389-4406.e10.
De Los Santos MC, Dragomir MP & Calin GA.
The role of exosomal long non-coding RNAs in cancer drug resistance.
Cancer Drug Resist (2019) 2:1178-1192.
Review exRNA and EV Biology exRNA Biology Grant TR000943
Yokoi A et al.
Mechanisms of nuclear content loading to exosomes.
Sci Adv (2019) 5:eaax8849.
exRNA and EV Biology EV Biology Grant CA179514 Grant TR000943
Dias MM et al.
GLS2 is protumorigenic in breast cancers.
Oncogene (2020) 39:690-702.
Fabbri M et al.
Decrypting noncoding RNA interactions, structures, and functional networks.
Genome Res (2019) 29:1377-1388.
exRNA and EV Biology exRNA Biology Grant TR000943 Grant CA179564
Bach DH, Zhang W & Sood AK.
Chromosomal instability in tumor initiation and development.
Cancer Res (2019) 79:3995-4002.
Chen X et al.
Identifying and targeting angiogenesis-related microRNAs in ovarian cancer.
Oncogene (2019) 38:6095-6108.
Petrescu GED et al.
MicroRNA based theranostics for brain cancer: Basic principles.
J Exp Clin Cancer Res (2019) 38:231.
Bayraktar R, Bertilaccio MTS & Calin GA.
The interaction between two worlds: microRNAs and Toll-Like Receptors.
Front Immunol (2019) 10:1053.
GnRH-R-targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition.
Mol Cancer Ther (2019) 18:969-979.
Gonzalez-Villasana V et al.
Presence of circulating miR-145, miR-155, and miR-382 in exosomes isolated from serum of breast cancer patients and healthy donors.
Dis Markers (2019) 2019:6852917.
Biomarkers Grant TR000943
Bach DH, Lee SK & Sood AK.
Circular RNAs in Cancer.
Mol Ther Nucleic Acids (2019) 16:118-129.
Review exRNA Biology Biomarkers Therapeutics Grant TR000943
Rodriguez-Aguayo C et al.
PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.
EBioMedicine (2019) 40:290-304.
Varkaris A et al.
Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer.
Br J Cancer (2019) 120:340-345.
Gulei D et al.
CRISPR-based RNA editing: Diagnostic applications and therapeutic options.
Expert Rev Mol Diagn (2019) 19:83-88.
LaFargue CJ et al.
Exploring and comparing adverse events between PARP inhibitors.
Lancet Oncol (2019) 20:e15-e28.
Review Grant TR000943
Cortez MA et al.
Role of miRNAs in immune responses and immunotherapy in cancer.
Genes Chromosomes Cancer (2019) 58:244-253.
Related Pathway
Villar-Prados A et al.
Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4.
Mol Cancer Ther (2019) 18:421-436.
Van Roosbroeck K et al.
The involvement of microRNA in the pathogenesis of Richter syndrome.
Haematologica (2019) 104:1004-1015.
Hisamatsu T et al.
PRKRA/PACT expression promotes chemoresistance of mucinous ovarian cancer.
Mol Cancer Ther (2019) 18:162-172.
Shen P et al.
Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling.
Mol Oncol (2018) 12:1856-1870.
Grant TR000943 Grant DA036134
Monroig-Bosque PDC et al.
OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.
Sci Rep (2018) 8:13106.
Grant CA179512 Grant TR000943
Dragomir M, Chen B & Calin GA.
Exosomal lncRNAs as new players in cell-to-cell communication.
Transl Cancer Res (2018) 7:S243-S252.
Review exRNA and EV Biology Grant TR000943
Silva AM et al.
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response.
Theranostics (2018) 8:3902-3917.
Biomarkers Grant CA179563 Grant TR000943
Gharpure KM et al.
FABP4 as a key determinant of metastatic potential of ovarian cancer.
Nat Commun (2018) 9:2923.
Umamaheswaran S et al.
Stress, inflammation, and eicosanoids: an emerging perspective.
Cancer Metastasis Rev (2018) 37:203-211.
Zhang Q et al.
Mutant KRAS exosomes alter the metabolic state of recipient colonic epithelial cells.
Cell Mol Gastroenterol Hepatol (2018) 5:627-629.e6.
Dragomir M & Calin GA.
Circular RNAs in cancer – Lessons learned from microRNAs.
Front Oncol (2018) 8:179.
Review exRNA and EV Biology exRNA Biology Grant TR000914 Grant TR000943
Lyons YA et al.
Immune cell profiling in cancer: Molecular approaches to cell-specific identification.
NPJ Precis Oncol (2017) 1:26.
Yeung TL et al.
Systematic identification of druggable epithelial-stromal crosstalk signaling networks in ovarian cancer.
J Natl Cancer Inst (2019) 111:272-282.
Grant CA179563 Grant TR000943
Haemmerle M et al.
The platelet lifeline to cancer: Challenges and opportunities.
Cancer Cell (2018) 33:965-983.
Shah MY et al.
Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.
Genome Res (2018) 28:432-447.
Grant TR000943 Grant HL126497
Filant J et al.
Isolation of extracellular RNA from serum/plasma.
Methods Mol Biol (2018) 1740:43-57.
Resources and Technology Grant TR000901 Grant TR000906 Grant TR000943 Grant TR000890 Grant HL126494
Velazquez-Torres G et al.
A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.
Nat Commun (2018) 9:461.
McKenzie JA et al.
The effect of topoisomerase I inhibitors on the efficacy of T-cell-based cancer immunotherapy.
J Natl Cancer Inst (2018) 110:777-786.
Kanlikilicer P et al.
Therapeutic targeting of AXL receptor tyrosine kinase inhibits tumor growth and intraperitoneal metastasis in ovarian cancer models.
Mol Ther Nucleic Acids (2017) 9:251-262.
Soni A et al.
Study protocol for Smartphone Monitoring for Atrial fibrillation in Real-Time in India (SMART-India): a community-based screening and referral programme.
BMJ Open (2017) 7:e017668.
Grant TR000943 Grant TR000921
RNA interference-based therapy and its delivery systems.
Cancer Metastasis Rev (2018) 37:107-124.
Therapeutics Grant CA179563 Grant TR000943
Noh K et al.
Differential effects of EGFL6 on tumor versus wound angiogenesis.
Cell Rep (2017) 21:2785-2795.
Grant TR000943 Grant TR000884
Vannini I et al.
Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.
Nat Commun (2017) 8:1801.
Lu Y et al.
MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels.
Cancer Res (2018) 78:64-74.
Grant TR000901 Grant TR000943
Ren A, Micura R & Patel DJ.
Structure-based mechanistic insights into catalysis by small self-cleaving ribozymes.
Curr Opin Chem Biol (2017) 41:71-83.
Grant TR000943 Grant CA179564
Amorim MG et al.
A total transcriptome profiling method for plasma-derived extracellular vesicles: Applications for liquid biopsies.
Sci Rep (2017) 7:14395.
Resources and Technology Grant TR000943 Grant CA179564
Mitamura T et al.
Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).
Oncogene (2018) 37:722-731.
Willinger CM et al.
MicroRNA signature of cigarette smoking and evidence for a putative causal role of microRNAs in smoking-related inflammation and target organ damage.
Circ Cardiovasc Genet (2017) 10:5.
Bayraktar R, Van Roosbroeck K & Calin GA.
Cell-to-cell communication: microRNAs as hormones.
Mol Oncol (2017) 11:1673-1686.
To Wnt or lose: The missing non-coding linc in colorectal cancer.
Int J Mol Sci (2017) 18:9.
Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.
Cell Discov (2017) 3:17029.
Grant TR000931 Grant TR000943
Figueroa J et al.
Exosomes from glioma-associated mesenchymal stem cells increase the tumorigenicity of glioma stem-like cells via transfer of miR-1587.
Cancer Res (2017) 77:5808-5819.
exRNA and EV Biology EV Biology Grant TR000928 Grant TR000943
Dalton HJ et al.
Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression.
Clin Cancer Res (2017) 23:7034-7046.
Wu AY & Lai CP.
Tracking extracellular vesicles delivery and RNA translation using multiplexed reporters.
Methods Mol Biol (2017) 1660:255-265.
Resources and Technology Grant CA179563 Grant TR000943
Vasilescu C et al.
Circulating miRNAs in sepsis-A network under attack: An in-silico prediction of the potential existence of miRNA sponges in sepsis.
PLoS ONE (2017) 12:e0183334.
Wu X et al.
The many faces of long noncoding RNAs in cancer.
Antioxid Redox Signal (2018) 29:922-935.
Gogakos T et al.
Characterizing expression and processing of precursor and mature human tRNAs by hydro-tRNAseq and PAR-CLIP.
Cell Rep (2017) 20:1463-1475.
Resources and Technology Grant TR000943 Grant CA179564 Grant TR000933
Fleming ND et al.
Phase II trial of bevacizumab with dose-dense paclitaxel as first-line treatment in patients with advanced ovarian cancer.
Gynecol Oncol (2017) 147:41-46.
Grant TR000943 Grant TR000933
Sardana M et al.
Clinical and echocardiographic correlates of Left Atrial Function Index: the Framingham offspring study.
J Am Soc Echocardiogr (2017) 30:904-912.e2.
Denizli M et al.
Chitosan nanoparticles for miRNA delivery.
Methods Mol Biol (2017) 1632:219-230.
Fabris L & Calin GA.
Understanding the genomic ultraconservations: T-UCRs and cancer.
Int Rev Cell Mol Biol (2017) 333:159-172.
Grant TR000914 Grant TR000943
Saugstad JA et al.
Analysis of extracellular RNA in cerebrospinal fluid.
J Extracell Vesicles (2017) 6:1317577.
Resources and Technology Grant TR000943 Grant TR000903
Sarkar S et al.
PRKCI promotes immune suppression in ovarian cancer.
Genes Dev (2017) 31:1109-1121.
Rigoutsos I et al.
N-BLR, a primate-specific non-coding transcript, leads to colorectal cancer invasion and migration.
Genome Biol (2017) 18:98.
Dendritic cell-derived extracellular vesicles mediate mesenchymal stem/stromal cell recruitment.
Sci Rep (2017) 7:1667.
Bruno S et al.
Renal regenerative potential of different extracellular vesicle populations derived from bone marrow mesenchymal stromal cells.
Tissue Eng Part A (2017) 23:1262-1273.
exRNA and EV Biology EV Biology Therapeutics Grant TR000943
Fuentes-Mattei E et al.
Plasma viral miRNAs indicate a high prevalence of occult viral infections.
EBioMedicine (2017) 20:182-192.
Klingenberg M et al.
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.
J Hepatol (2017) 67:603-618.
Review Biomarkers Grant TR000943 Grant TR000884
Related Pathways: 1, 2
Rashed MH et al.
Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget (2017) 8:20145-20164.
Rabinowicz N et al.
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer.
Oncotarget (2017) 8:27380-27392.
Wagner MJ et al.
Preclinical mammalian safety studies of EPHARNA (DOPC nanoliposomal EphA2-targeted siRNA).
Mol Cancer Ther (2017) 16:1114-1123.
Grant TR000943 Grant HL126496
Gladek I et al.
HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.
Genes Chromosomes Cancer (2017) 56:439-452.
Maas SL, Breakefield XO & Weaver AM.
Extracellular vesicles: Unique intercellular delivery vehicles.
Trends Cell Biol (2017) 27:172-188.
Review exRNA and EV Biology EV Biology Therapeutics Grant CA179563 Grant CA179514 Grant TR000943
Krzeszinski JY et al.
Lipid osteoclastokines regulate breast cancer bone metastasis.
Endocrinology (2017) 158:477-489.
Grant TR000943 Grant TR000923
Combining anti-miR-155 with chemotherapy for the treatment of lung cancers.
Clin Cancer Res (2017) 23:2891-2904.
Pi F et al.
RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery.
Nanomedicine (2017) 13:1183-1193.
Grant TR000888 Grant TR000943
Kaczor-Urbanowicz KE et al.
Emerging technologies for salivaomics in cancer detection.
J Cell Mol Med (2017) 21:640-647.
Review Biomarkers Grant TR000943 Grant TR000923
Yang L et al.
Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth.
Cell Metab (2016) 24:685-700.
Previs RA et al.
The rise of genomic profiling in ovarian cancer.
Expert Rev Mol Diagn (2016) 16:1337-1351.
Hatakeyama H et al.
Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers.
Cell Rep (2016) 17:1621-1631.
Ohtsuka M et al.
H19 noncoding RNA, an independent prognostic factor, regulates essential Rb-E2F and CDK8-beta-catenin signaling in colorectal cancer.
EBioMedicine (2016) 13:113-124.
Mangala LS et al.
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.
JCI Insight (2016) 1:e87754.
Ubiquitous release of exosomal tumor suppressor miR-6126 from ovarian cancer cells.
Cancer Res (2016) 76:7194-7207.
exRNA and EV Biology EV Biology Biomarkers Grant TR000943
High burden of unrecognized atrial fibrillation in rural india: An innovative community-based cross-sectional screening program.
JMIR Public Health Surveill (2016) 2:e159.
Giza DE et al.
Cellular and viral microRNAs in sepsis: Mechanisms of action and clinical applications.
Cell Death Differ (2016) 23:1906-1918.
microRNA therapeutics in cancer – an emerging concept.
EBioMedicine (2016) 12:34-42.
Review Therapeutics Grant TR000901 Grant TR000943
Zhou J et al.
A novel compound ARN-3236 inhibits salt-inducible kinase 2 and sensitizes ovarian cancer cell lines and xenografts to paclitaxel.
Clin Cancer Res (2017) 23:1945-1954.
Huang Y et al.
Anti-tumor and anti-angiogenic effects of aspirin-PC in ovarian cancer.
Mol Cancer Ther (2016) 15:2894-2904.
Ciccone M & Calin GA.
MicroRNAs in chronic lymphocytic leukemia: An old disease with new genetic insights.
MicroRNA (2016) 5:106-112.
Harjes U et al.
Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4.
Oncogene (2017) 36:912-921.
Miranda F et al.
Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche.
Cancer Cell (2016) 30:273-289.
Grant TR000902 Grant TR000943
Hodgkin lymphoma cells have a specific long noncoding RNA expression pattern.
Am J Pathol (2016) 186:2251-3.
Zhao Z et al.
An arginine finger regulates the sequential action of asymmetrical hexameric ATPase in the double-stranded DNA translocation motor.
Mol Cell Biol (2016) 36:2514-23.
Grant TR000943 Grant TR000875
Paladini L et al.
Targeting microRNAs as key modulators of tumor immune response.
J Exp Clin Cancer Res (2016) 35:103.
Review exRNA and EV Biology exRNA Biology Therapeutics Grant TR000943 Grant TR000875
Higginbotham JN et al.
Identification and characterization of EGF receptor in individual exosomes by Fluorescence-Activated Vesicle Sorting.
J Extracell Vesicles (2016) 5:29254.
Resources and Technology Grant CA179514 Grant TR000943
Srivastava A et al.
Exploitation of exosomes as nanocarriers for gene-, chemo-, and immune-therapy of cancer.
J Biomed Nanotechnol (2016) 12:1159-73.
Review Therapeutics Grant TR000943
Zhang HG et al.
Isolation, identification, and characterization of novel nanovesicles.
Oncotarget (2016) 7:41346-41362.
exRNA and EV Biology EV Biology Grant TR000943 Grant TR000891
Chaluvally-Raghavan P et al.
Direct upregulation of STAT3 by microRNA-551b-3p deregulates growth and metastasis of ovarian cancer.
Cell Rep (2016) 15:1493-504.
Therapeutics Grant TR000880 Grant TR000943
FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.
J Clin Invest (2016) 126:1885-96.
MicroRNAs in myeloid hematological malignancies.
Curr Genomics (2015) 16:336-48.
Yan KK et al.
Cross-disciplinary network comparison: Matchmaking between hairballs.
Cell Syst (2016) 2:147-157.
Wu SY et al.
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Nat Commun (2016) 7:11169.
exRNA and EV Biology exRNA Biology Therapeutics Grant TR000943
Van Roosbroeck K & Calin GA.
MicroRNAs in chronic lymphocytic leukemia: miRacle or miRage for prognosis and targeted therapies?
Semin Oncol (2016) 43:209-14.
Pan Y et al.
miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer.
Oncotarget (2016) 7:25930-48.
Parasramka MA et al.
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma.
Pharmacol Ther (2016) 161:67-78.
Review Therapeutics Grant TR000943 Grant TR000884
Huang J et al.
Dll4 inhibition plus aflibercept markedly reduces ovarian tumor growth.
Mol Cancer Ther (2016) 15:1344-52.
Almeida MI & Calin GA.
The miR-143/miR-145 cluster and the tumor microenvironment: Unexpected roles.
Genome Med (2016) 8:29.
Review exRNA and EV Biology Grant TR000943 Grant TR000921
Tanriverdi K et al.
Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative Polymerase Chain Reaction.
Anal Biochem (2016) 501:66-74.
Resources and Technology Grant TR000943 Grant TR000921 Grant HL126495
Rytelewski M et al.
Reciprocal positive selection for weakness – preventing olaparib resistance by inhibiting BRCA2.
Oncotarget (2016) 7:20825-39.
Zaborowski MP et al.
Extracellular vesicles: Composition, biological relevance, and methods of study.
Bioscience (2015) 65:783-797.
Review exRNA and EV Biology Resources and Technology Grant CA179563 Grant TR000943
Zhang X et al.
Potential transfer of polyglutamine and CAG-repeat RNA in extracellular vesicles in Huntington”s disease: Background and evaluation in cell culture.
Cell Mol Neurobiol (2016) 36:459-70.
Olivieri M et al.
Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.
Oncotarget (2016) 7:20636-54.
Kundu A et al.
Relation of atrial fibrillation in acute myocardial infarction to in-hospital complications and early hospital readmission.
Am J Cardiol (2016) 117:1213-8.
Rupaimoole R et al.
miRNA deregulation in cancer cells and the tumor microenvironment.
Cancer Discov (2016) 6:235-46.
Sun Y et al.
Examining plasma microRNA markers for colorectal cancer at different stages.
Oncotarget (2016) 7:11434-49.
Biomarkers Grant TR000901 Grant TR000943
Redis RS et al.
Allele-specific reprogramming of cancer metabolism by the long non-coding RNA CCAT2.
Mol Cell (2016) 61:520-34.
Pua HH et al.
MicroRNAs 24 and 27 suppress allergic inflammation and target a network of regulators of T Helper 2 cell-associated cytokine production.
Immunity (2016) 44:821-32.
Grant TR000943 Grant HL126493
Hansen JM, Coleman RL & Sood AK.
Targeting the tumour microenvironment in ovarian cancer.
Eur J Cancer (2016) 56:131-43.
Guo P et al.
Biological nanomotors with a revolution, linear, or rotation motion mechanism.
Microbiol Mol Biol Rev (2016) 80:161-86.
Fabris L et al.
The potential of microRNAs as prostate cancer biomarkers.
Eur Urol (2016) 70:312-22.
Review Biomarkers Grant TR000901 Grant TR000943
Yuan T et al.
Plasma extracellular RNA profiles in healthy and cancer patients.
Sci Rep (2016) 6:19413.
Resources and Technology Grant TR000943 Grant TR000884
Ben-Dov IZ et al.
Cell and microvesicle urine microRNA deep sequencing profiles from healthy individuals: Observations with potential impact on biomarker studies.
PLoS ONE (2016) 11:e0147249.
Mitamura T, Gourley C & Sood AK.
Prediction and failure of anti-angiogenesis escape.
Gynecol Oncol (2016) 141:80-5.
Lener T et al.
Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper.
J Extracell Vesicles (2015) 4:30087.
Highly Cited (600+) Review Therapeutics Grant TR000880 Grant TR000943 Grant TR000884
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Oncogene (2016) 35:4312-20. Related blog post
McManus DD et al.
Reliability of predicting early hospital readmission after discharge for an acute coronary syndrome using claims-based data.
Am J Cardiol (2016) 117:501-7.
Long noncoding RNA ceruloplasmin promotes cancer growth by altering glycolysis.
Cell Rep (2015) 13:2395-402.
Giza DE & Calin GA
microRNA and Chronic Lymphocytic Leukemia.
Adv Exp Med Biol (2015) 889:23-40.
Review exRNA and EV Biology exRNA Biology Grant TR000943 Grant CA179564
Sercombe L et al.
Advances and challenges of liposome assisted drug delivery.
Front Pharmacol (2015) 6:286.
Highly Cited (950+) Therapeutics Grant TR000943 Grant TR000884
Silva A, Bullock M & Calin G.
The clinical relevance of long non-coding RNAs in cancer.
Cancers (2015) 7:2169-82.
exRNA and EV Biology Grant TR000943
Dual metronomic chemotherapy with nab-paclitaxel and topotecan has potent antiangiogenic activity in ovarian cancer.
Mol Cancer Ther (2015) 14:2677-86.
Bucur O et al.
An updated h-index measures both the primary and total scientific output of a researcher.
Discoveries (2015) 3:3.
Wei S & Williams Z.
Rapid short-read sequencing and aneuploidy detection using MinION nanopore technology.
Genetics (2016) 202:37-44.
Pradeep S et al.
Erythropoietin stimulates tumor growth via EphB4.
Cancer Cell (2015) 28:610-22.
Schwarzenbach H et al.
Data normalization strategies for microRNA quantification.
Clin Chem (2015) 61:1333-42.
Monroig-Bosque Pdel C, Rivera CA & Calin GA.
MicroRNAs in cancer therapeutics: “From the bench to the bedside”.
Expert Opin Biol Ther (2015) 15:1381-5.
Review Biomarkers Grant TR000943
Chira S et al.
Progresses towards safe and efficient gene therapy vectors.
Oncotarget (2015) 6:30675-703.
Laurent LC et al.
Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.
J Extracell Vesicles (2015) 4:26533.
Review Biomarkers Resources and Technology Grant TR000901 Grant TR000943
Giza DE, Vasilescu C & Calin GA.
Key principles of miRNA involvement in human diseases.
Discoveries (Craiova) (2014) 2:e34.
MicroRNA processing and human cancer.
J Clin Med (2015) 4:1651-67.
Ferrajoli A et al.
Epstein-Barr virus microRNAs are expressed in patients with chronic lymphocytic leukemia and correlate with overall survival.
EBioMedicine (2015) 2:572-82.
Nagaraja AS et al.
Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis.
Oncogene (2016) 35:2390-7.
Matsuo K et al.
Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma.
Eur J Cancer (2015) 51:1978-88.
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