New pathways for the exRNA portal at WikiPathways

The exRNA portal at WikiPathways continues to grow. It now includes 46 exRNA-related pathways, including 15 from publications by the Extracellular RNA Communication consortium. We are committed to capturing every published pathway figure from the consortium as a properly modeled pathway at WikiPathways. If your work involves pathways, especially if you are publishing it, then look into contributing to WikiPathways.

The latest pathways to be curated from consortium publications are

• 1) EV release from cardiac cells and their functional effects (WP3297),
• 2) the Rac1/Pak1/p38/MMP-2 pathway (WP3303),
• 3) eIF5A regulation in response to inhibition of the nuclear export system (WP3302), and
• 4) MFAP5-mediated ovarian cancer cell motility and invasiveness (WP3301).

The goal of the Wikipathways exRNA portal is to build a collection of pathway models for exRNA researchers to use for illustration, data visualization, and analysis. Each pathway is a self-contained data model that connects to identifier and annotation databases. In addition to providing static images for figures and presentations, these pathways can also be used by bioinformatics and network analysis packages such as Cytoscape and PathVisio. Furthermore, as a wiki, anyone can sign up to improve and grow the content. We invite you all to edit, fix, and add to the pathway models in the exRNA portal at WikiPathways.